Publications by authors named "Scott M DeWire"

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Unexpected Potency Differences between B-Cell-Activating Factor (BAFF) Antagonist Antibodies against Various Forms of BAFF: Trimer, 60-Mer, and Membrane-Bound.
Amy M Nicoletti, Cynthia Hess Kenny, Ashraf M Khalil, Qi Pan, Kerry L M Ralph, Scott M DeWire

J Pharmacol Exp Ther· October 2016

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Structure-activity relationships and discovery of a G protein biased μ opioid receptor ligand, [(3-methoxythiophen-2-yl)methyl]({2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro-[4.5]decan-9-yl]ethyl})amine (TRV130), for the treatment of acute severe pain.
Xiao-Tao Chen, Philip Pitis, Guodong Liu, Catherine Yuan, Dimitar Gotchev, Scott M Dewire

J Med Chem· October 2013

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A G protein-biased ligand at the μ-opioid receptor is potently analgesic with reduced gastrointestinal and respiratory dysfunction compared with morphine.
Scott M DeWire, Dennis S Yamashita, David H Rominger, Guodong Liu, Conrad L Cowan

J Pharmacol Exp Ther· March 2013

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Quantifying ligand bias at seven-transmembrane receptors.
Sudarshan Rajagopal, Seungkirl Ahn, David H Rominger, William Gowen-MacDonald, Christopher M Lam, Scott M Dewire

Mol Pharmacol· September 2011

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Biased ligands for better cardiovascular drugs: dissecting G-protein-coupled receptor pharmacology.
Scott M DeWire, Jonathan D Violin

Circ Res· July 2011

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Selectively engaging β-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance.
Jonathan D Violin, Scott M DeWire, Dennis Yamashita, David H Rominger, Lisa Nguyen

J Pharmacol Exp Ther· December 2010

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beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice.
Robert W Walters, Arun K Shukla, Jeffrey J Kovacs, Jonathan D Violin, Scott M DeWire

J Clin Invest· May 2009

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Beta-arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration.
Jihee Kim, Lisheng Zhang, Karsten Peppel, Jiao-Hui Wu, David A Zidar, Scott M DeWire

Circ Res· July 2008

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Beta-arrestin-mediated signaling regulates protein synthesis.
Scott M DeWire, Jihee Kim, Erin J Whalen, Seungkirl Ahn, Minyong Chen

J Biol Chem· April 2008

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A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling.
James W Wisler, Scott M DeWire, Erin J Whalen, Jonathan D Violin, Matthew T Drake

Proc Natl Acad Sci U S A· October 2007

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Beta-arrestins and cell signaling.
Scott M DeWire, Seungkirl Ahn, Robert J Lefkowitz, Sudha K Shenoy

Annu Rev Physiol· April 2007

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G protein-coupled receptor kinase and beta-arrestin-mediated desensitization of the angiotensin II type 1A receptor elucidated by diacylglycerol dynamics.
Jonathan D Violin, Scott M Dewire, William G Barnes, Robert J Lefkowitz

J Biol Chem· November 2006

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Whole-genome transcription profiling of rhesus monkey rhadinovirus.
Dirk P Dittmer, Carlos M Gonzalez, Wolfgang Vahrson, Scott M DeWire, Rebecca Hines-Boykin

J Virol· July 2005

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The latency-associated nuclear antigen of rhesus monkey rhadinovirus inhibits viral replication through repression of Orf50/Rta transcriptional activation.
Scott M DeWire, Blossom Damania

J Virol· March 2005

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Comparison of the Rta/Orf50 transactivator proteins of gamma-2-herpesviruses.
Blossom Damania, Joseph H Jeong, Brian S Bowser, Scott M DeWire, Michelle R Staudt

J Virol· May 2004

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The Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) K1 protein induces expression of angiogenic and invasion factors.
Ling Wang, Naohiro Wakisaka, Christine C Tomlinson, Scott M DeWire, Stuart Krall

Cancer Res· April 2004

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Rhesus monkey rhadinovirus (RRV): construction of a RRV-GFP recombinant virus and development of assays to assess viral replication.
Scott M DeWire, Eric S Money, Stuart P Krall, Blossom Damania

Virology· July 2003

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Transcriptional regulation of the K1 gene product of Kaposi's sarcoma-associated herpesvirus.
Brian S Bowser, Scott M DeWire, Blossom Damania

J Virol· December 2002

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Kinetics of expression of rhesus monkey rhadinovirus (RRV) and identification and characterization of a polycistronic transcript encoding the RRV Orf50/Rta, RRV R8, and R8.1 genes.
Scott M DeWire, Michael A McVoy, Blossom Damania

J Virol· October 2002

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