Publications by authors named "Piet Borst"

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Adventures With Parasites, Metabolism, Inborn Errors, and Cancer: The 2023 Lasker-Koshland Special Achievement Award in Medical Science.
Piet Borst

JAMA· October 2023

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Looking back at multidrug resistance (MDR) research and ten mistakes to be avoided when writing about ABC transporters in MDR.
Piet Borst

FEBS Lett· December 2020

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The malate-aspartate shuttle (Borst cycle): How it started and developed into a major metabolic pathway.
Piet Borst

IUBMB Life· November 2020

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Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.
Ewa Gogola, Alexandra A Duarte, Julian R de Ruiter, Wouter W Wiegant, Jonas A Schmid, Piet Borst

Cancer Cell· June 2019

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PXE, a Mysterious Inborn Error Clarified.
Piet Borst, András Váradi, Koen van de Wetering

Trends Biochem Sci· February 2019

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Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.
Ewa Gogola, Alexandra A Duarte, Julian R de Ruiter, Wouter W Wiegant, Jonas A Schmid, Piet Borst

Cancer Cell· June 2018

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BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance.
Alexandra A Duarte, Ewa Gogola, Norman Sachs, Marco Barazas, Stefano Annunziato, Piet Borst

Nat Methods· February 2018

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Selected Alkylating Agents Can Overcome Drug Tolerance of G-like Tumor Cells and Eradicate BRCA1-Deficient Mammary Tumors in Mice.
Marina Pajic, Sohvi Blatter, Charlotte Guyader, Maaike Gonggrijp, Ariena Kersbergen, Piet Borst

Clin Cancer Res· November 2017

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Maxi-circles, glycosomes, gene transposition, expression sites, transsplicing, transferrin receptors and base J.
Piet Borst

Mol Biochem Parasitol· December 2016

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HELB Is a Feedback Inhibitor of DNA End Resection.
Ján Tkáč, Guotai Xu, Hemanta Adhikary, Jordan T F Young, David Gallo, Piet Borst

Mol Cell· February 2016

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ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs.
Robert S Jansen, Sunny Mahakena, Marcel de Haas, Piet Borst, Koen van de Wetering

J Biol Chem· December 2015

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Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs.
Rosa Planells-Cases, Darius Lutter, Charlotte Guyader, Nora M Gerhards, Florian Ullrich, Piet Borst

EMBO J· December 2015

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REV7 counteracts DNA double-strand break resection and affects PARP inhibition.
Guotai Xu, J Ross Chapman, Inger Brandsma, Jingsong Yuan, Martin Mistrik, Piet Borst

Nature· May 2015

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BRCA2-deficient sarcomatoid mammary tumors exhibit multidrug resistance.
Janneke E Jaspers, Wendy Sol, Ariena Kersbergen, Andreas Schlicker, Charlotte Guyader, Piet Borst

Cancer Res· February 2015

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Defining the sequence requirements for the positioning of base J in DNA using SMRT sequencing.
Paul-Andre Genest, Loren Baugh, Alex Taipale, Wanqi Zhao, Sabrina Jan, Piet Borst

Nucleic Acids Res· February 2015

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ABCC6-mediated ATP secretion by the liver is the main source of the mineralization inhibitor inorganic pyrophosphate in the systemic circulation-brief report.
Robert S Jansen, Suzanne Duijst, Sunny Mahakena, Daniela Sommer, Flóra Szeri, Piet Borst

Arterioscler Thromb Vasc Biol· September 2014

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P-glycoprotein ABCB1: a major player in drug handling by mammals.
Piet Borst, Alfred H Schinkel

J Clin Invest· October 2013

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EZN-2208 (PEG-SN38) overcomes ABCG2-mediated topotecan resistance in BRCA1-deficient mouse mammary tumors.
Serge A L Zander, Wendy Sol, Lee Greenberger, Yixian Zhang, Olaf van Tellingen, Piet Borst

PLoS One· February 2013

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Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.
Janneke E Jaspers, Ariena Kersbergen, Ute Boon, Wendy Sol, Liesbeth van Deemter, Piet Borst

Cancer Discov· January 2013

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Drug resistance in the mouse cancer clinic.
Sven Rottenberg, Piet Borst

Drug Resist Updat· August 2012

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Lack of ABCG2 shortens latency of BRCA1-deficient mammary tumors and this is not affected by genistein or resveratrol.
Serge A L Zander, Ariena Kersbergen, Wendy Sol, Maaike Gonggrijp, Koen van de Wetering, Piet Borst

Cancer Prev Res (Phila)· August 2012

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Binding of the J-binding protein to DNA containing glucosylated hmU (base J) or 5-hmC: evidence for a rapid conformational change upon DNA binding.
Tatjana Heidebrecht, Alexander Fish, Eleonore von Castelmur, Kenneth A Johnson, Giuseppe Zaccai, Piet Borst

J Am Chem Soc· August 2012

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Glucosylated hydroxymethyluracil, DNA base J, prevents transcriptional readthrough in Leishmania.
Henri G A M van Luenen, Carol Farris, Sabrina Jan, Paul-Andre Genest, Pankaj Tripathi, Piet Borst

Cell· August 2012

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Impact of intertumoral heterogeneity on predicting chemotherapy response of BRCA1-deficient mammary tumors.
Sven Rottenberg, Marieke A Vollebergh, Bas de Hoon, Jorma de Ronde, Philip C Schouten, Piet Borst

Cancer Res· May 2012

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Cancer drug pan-resistance: pumps, cancer stem cells, quiescence, epithelial to mesenchymal transition, blocked cell death pathways, persisters or what?
Piet Borst

Open Biol· May 2012

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