Publications by authors named "Piet Swart"

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Insights into Praziquantel Metabolism and Potential Enantiomeric Cytochrome P450-Mediated Drug-Drug Interaction.
Gloria Vendrell-Navarro, Holger Scheible, Floriane Lignet, Howard Burt, Christian Luepfert, Piet Swart

Drug Metab Dispos· June 2020

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A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the "Metabolites in Safety Testing" Regulatory Guidance.
Simone Schadt, Bojan Bister, Swapan K Chowdhury, Christoph Funk, Cornelis E C A Hop, Piet Swart

Drug Metab Dispos· June 2018

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The impact of early human data on clinical development: there is time to win.
Piet Swart, Frederic Lozac'h, Marjorie Simon, Esther van Duijn, Wouter H J Vaes

Drug Discov Today· June 2016

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ADME studies of [5-(3)H]-2'-O-methyluridine nucleoside in mice: a building block in siRNA therapeutics.
Frederic Lozac'h, Jesper Christensen, Thomas Faller, Esther van de Kerkhof, Joel Krauser, Piet Swart

Pharmacol Res Perspect· February 2016

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Absorption, distribution, metabolism, and excretion of [(14)C]BYL719 (alpelisib) in healthy male volunteers.
Alexander James, Lars Blumenstein, Ulrike Glaenzel, Yi Jin, Arnold Demailly, Piet Swart

Cancer Chemother Pharmacol· October 2015

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Phenotypic and metabolic investigation of a CSF-1R kinase receptor inhibitor (BLZ945) and its pharmacologically active metabolite.
Joel A Krauser, Yi Jin, Markus Walles, Ulrike Pfaar, James Sutton, Piet Swart

Xenobiotica· February 2015

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Phase II metabolism in human skin: skin explants show full coverage for glucuronidation, sulfation, N-acetylation, catechol methylation, and glutathione conjugation.
Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch

Drug Metab Dispos· January 2015

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Aldehyde oxidase activity in fresh human skin.
Nenad Manevski, Kamal Kumar Balavenkatraman, Barbara Bertschi, Piet Swart, Markus Walles

Drug Metab Dispos· December 2014

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An iron stable isotope comparison between human erythrocytes and plasma.
Friedhelm von Blanckenburg, Marcus Oelze, Dietmar G Schmid, Kirsten van Zuilen, Hans-Peter Gschwind, Piet Swart

Metallomics· November 2014

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Iron uptake and ferrokinetics in healthy male subjects of an iron-based oral phosphate binder (SBR759) labeled with the stable isotope (58)Fe.
Hans-Peter Gschwind, Dietmar G Schmid, Friedhelm von Blanckenburg, Marcus Oelze, Kirsten van Zuilen, Piet Swart

Metallomics· November 2014

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Absorption, distribution, metabolism, and excretion (ADME) of ¹⁴C-sonidegib (LDE225) in healthy volunteers.
Markus Zollinger, Frédéric Lozac'h, Eunju Hurh, Corinne Emotte, Hounayda Bauly, Piet Swart

Cancer Chemother Pharmacol· July 2014

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Biodistribution and metabolism studies of lipid nanoparticle-formulated internally [3H]-labeled siRNA in mice.
Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Piet Swart

Drug Metab Dispos· March 2014

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Metabolism and disposition of the metabotropic glutamate receptor 5 antagonist (mGluR5) mavoglurant (AFQ056) in healthy subjects.
Markus Walles, Thierry Wolf, Yi Jin, Michael Ritzau, Luc Alexis Leuthold, Piet Swart

Drug Metab Dispos· September 2013

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Metabolism of patupilone in patients with advanced solid tumor malignancies.
Kevin R Kelly, Markus Zollinger, Frédéric Lozac'h, Eugene Tan, Alain Mita, Piet Swart

Invest New Drugs· June 2013

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Metabolism studies of unformulated internally [3H]-labeled short interfering RNAs in mice.
Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Piet Swart

Drug Metab Dispos· June 2013

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A unique automation platform for measuring low level radioactivity in metabolite identification studies.
Joel Krauser, Markus Walles, Thierry Wolf, Daniel Graf, Piet Swart

PLoS One· December 2012

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Pharmacokinetic interaction of solifenacin with an oral contraceptive containing ethinyl estradiol and levonorgestrel in healthy women: a double-blind, placebo-controlled study.
Miriam E J Taekema-Roelvink, Piet J Swart, Mirjam E Kuipers, Walter J J Krauwinkel, Nico Visser

Clin Ther· September 2005

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