Publications by authors named "Qianping Peng"

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Incidence and disability-adjusted life-years of infective endocarditis in China from 1990 to 2021: comparison with G20 based on the Global Burden of Disease Study 2021.
Yan Gu, Hong Chenliang, Zhu Weimin, Peng Qianping, Chong Liu

BMJ Open· July 2025

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Use of a carboxylesterase inhibitor of phenylmethanesulfonyl fluoride to stabilize epothilone D in rat plasma for a validated UHPLC-MS/MS assay.
Long Yuan, Yunlin Fu, Duxi Zhang, Yuan-Qing Xia, Qianping Peng

J Chromatogr B Analyt Technol Biomed Life Sci· October 2014

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Improved liquid-liquid extraction with inter-well volume replacement dilution workflow and its application to quantify BMS-927711 in rat dried blood spots by UHPLC-MS/MS.
Naiyu Zheng, Jianing Zeng, Qin C Ji, Aida Angeles, Adela Buzescu, Qianping Peng

J Pharm Biomed Anal· February 2014

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A rapid, accurate and robust UHPLC-MS/MS method for quantitative determination of BMS-927711, a CGRP receptor antagonist, in plasma in support of non-clinical toxicokinetic studies.
Naiyu Zheng, Jianing Zeng, Billy Akinsanya, Adela Buzescu, Yuan-Qing Xia, Qianping Peng

J Pharm Biomed Anal· September 2013

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A simplified and completely automated workflow for regulated LC-MS/MS bioanalysis using cap-piercing direct sampling and evaporation-free solid phase extraction.
Naiyu Zheng, Adela Buzescu, Stephanie Pasas-Farmer, Mark E Arnold, Zheng Ouyang, Qianping Peng

J Chromatogr B Analyt Technol Biomed Life Sci· March 2013

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A rugged and accurate liquid chromatography-tandem mass spectrometry method for the determination of asunaprevir, an NS3 protease inhibitor, in plasma.
Long Yuan, Hao Jiang, Zheng Ouyang, Yuan-Qing Xia, Jianing Zeng, Qianping Peng

J Chromatogr B Analyt Technol Biomed Life Sci· March 2013

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A convenient strategy for quantitative determination of drug concentrations in tissue homogenates using a liquid chromatography/tandem mass spectrometry assay for plasma samples.
Hao Jiang, Jianing Zeng, Naiyu Zheng, Hamza Kandoussi, Qianping Peng

Anal Chem· August 2011

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Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist.
Qingmei Hong, Raman K Bakshi, Brenda L Palucki, Min K Park, Zhixiong Ye, Qianping Peng

Bioorg Med Chem Lett· April 2011

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Discovery of highly potent and efficacious MC4R agonists with spiroindane N-Me-1,2,4-triazole privileged structures for the treatment of obesity.
Shuwen He, Zhixiong Ye, Peter H Dobbelaar, Raman K Bakshi, Qingmei Hong, Qianping Peng

Bioorg Med Chem Lett· November 2010

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Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity.
Shuwen He, Zhixiong Ye, Peter H Dobbelaar, Iyassu K Sebhat, Liangqin Guo, Qianping Peng

Bioorg Med Chem Lett· August 2010

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Discovery of potent, selective, and orally bioavailable 3H-spiro[isobenzofuran-1,4'-piperidine] based melanocortin subtype-4 receptor agonists.
Liangqin Guo, Zhixiong Ye, Jian Liu, Shuwen He, Raman K Bakshi, Qianping Peng

Bioorg Med Chem Lett· August 2010

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Synthesis and SAR of heterocyclic carboxylic acid isosteres based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity.
Mark Hadden, Allan Goodman, Cheng Guo, Peter R Guzzo, Alan J Henderson, Qianping Peng

Bioorg Med Chem Lett· May 2010

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Discovery of a spiroindane based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor agonist.
Shuwen He, Zhixiong Ye, Peter H Dobbelaar, Iyassu K Sebhat, Liangqin Guo, Qianping Peng

Bioorg Med Chem Lett· April 2010

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Synthesis and SAR of derivatives based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity.
Jian Liu, Shuwen He, Tianying Jian, Peter H Dobbelaar, Iyassu K Sebhat, Qianping Peng

Bioorg Med Chem Lett· April 2010

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Discovery of substituted biphenyl imidazoles as potent, bioavailable bombesin receptor subtype-3 agonists.
Shuwen He, Peter H Dobbelaar, Jian Liu, Tianying Jian, Iyassu K Sebhat, Qianping Peng

Bioorg Med Chem Lett· March 2010

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Synthesis and SAR of potent and orally bioavailable tert-butylpyrrolidine archetype derived melanocortin subtype-4 receptor modulators.
Liangqin Guo, Zhixiong Ye, Feroze Ujjainwalla, Heather L Sings, Iyassu K Sebhat, Qianping Peng

Bioorg Med Chem Lett· June 2008

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Discovery and activity of (1R,4S,6R)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-2-methyl-2-azabicyclo[2.2.2]octane-6-carboxamide (3, RY764), a potent and selective melanocortin subtype-4 receptor agonist.
Zhixiong Ye, Liangqin Guo, Khaled J Barakat, Patrick G Pollard, Brenda L Palucki, Qianping Peng

Bioorg Med Chem Lett· August 2005

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2-Piperazinecarboxamides as potent and selective melanocortin subtype-4 receptor agonists.
Brenda L Palucki, Min K Park, Ravi P Nargund, Rui Tang, Tanya MacNeil, Qianping Peng

Bioorg Med Chem Lett· April 2005

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Discovery of (2S)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-4-methyl-2-piperazinecarboxamide (MB243), a potent and selective melanocortin subtype-4 receptor agonist.
Brenda L Palucki, Min K Park, Ravi P Nargund, Zhixiong Ye, Iyassu K Sebhat, Qianping Peng

Bioorg Med Chem Lett· January 2005

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Comparison of the effects of perfusion in determining brain penetration (brain-to-plasma ratios) of small molecules in rats.
Judith E Fenyk-Melody, Xiaolan Shen, Qianping Peng, William Pikounis, Lawrence Colwell

Comp Med· August 2004

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