Publications by authors named "RL Walter"

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Perioperative Collagen IV-Targeted Ac2-26 Nanoparticles Enhance Anastomotic Healing in Acute Crohn's Disease-Like Colitis: A Preclinical Study on Systemic, Oral, and Rectal Delivery Routes.
Kamacay Cira, Vincent Vieregge, Sebastian Pollak, Jong Hyun Lee, Stefan Reischl, Robert Leon Walter

Ann Surg· September 2025

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Orally delivered biodegradable targeted inflammation resolving pectin-coated nanoparticles induce anastomotic healing post intestinal surgery.
Jong Hyun Lee, Stefan Reischl, Robert Leon Walter, Vincent Vieregge, Marie-Christin Weber

Sci Rep· November 2024

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Intestinal anastomotic healing models during experimental colitis.
J R E Miltschitzky, Z Clees, M-C Weber, V Vieregge, R L Walter

Int J Colorectal Dis· October 2021

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Structural and biophysical characterization of the Burkholderia pseudomallei IspF inhibitor L-tryptophan hydroxamate.
Joy M Blain, Dakota L Grote, Sydney M Watkins, Gashaw M Goshu, Chanté Muller, Richard L Walter

Bioorg Med Chem Lett· September 2021

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Ac2-26-Nanoparticles Induce Resolution of Intestinal Inflammation and Anastomotic Healing via Inhibition of NF-κB Signaling in a Model of Perioperative Colitis.
Stefan Reischl, Jong Hyun Lee, Joseph Raphael Elias Miltschitzky, Vincent Vieregge, Robert Leon Walter

Inflamm Bowel Dis· August 2021

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Low Level Pro-inflammatory Cytokines Decrease Connexin36 Gap Junction Coupling in Mouse and Human Islets through Nitric Oxide-mediated Protein Kinase Cδ.
Nikki L Farnsworth, Rachelle L Walter, Alireza Hemmati, Matthew J Westacott, Richard K P Benninger

J Biol Chem· February 2016

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The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants.
Maria K Tsoumpra, Joao R Muniz, Bobby L Barnett, Aaron A Kwaasi, Ewa S Pilka, Richard L Walter

Bone· December 2015

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Specific fluorine labeling of the HyHEL10 antibody affects antigen binding and dynamics.
Mauro Acchione, Yi-Chien Lee, Morgan E DeSantis, Claudia A Lipschultz, Alexander Wlodawer, Richard L Walter

Biochemistry· July 2012

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Identification of a glycogen synthase kinase-3β inhibitor that attenuates hyperactivity in CLOCK mutant mice.
Alan P Kozikowski, Hendra Gunosewoyo, Songpo Guo, Irina N Gaisina, Richard L Walter

ChemMedChem· September 2011

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Structure of human desArg-C5a.
William J Cook, Nicholas Galakatos, William C Boyar, Richard L Walter, Steven E Ealick

Acta Crystallogr D Biol Crystallogr· February 2010

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The crystal structures of the psychrophilic subtilisin S41 and the mesophilic subtilisin Sph reveal the same calcium-loaded state.
Orna Almog, Ana González, Noa Godin, Marina de Leeuw, Marlene J Mekel, Richard L Walter

Proteins· February 2009

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Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.
Artem G Evdokimov, Matthew Pokross, Richard L Walter, Marlene Mekel, Bobby L Barnett

Proteins· February 2007

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The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck).
Mark Sabat, John C VanRens, Matthew J Laufersweiler, Todd A Brugel, Jennifer Maier, Richard L Walter

Bioorg Med Chem Lett· December 2006

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The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-alpha production.
Mark Sabat, John C Vanrens, Michael P Clark, Todd A Brugel, Jennifer Maier, Richard L Walter

Bioorg Med Chem Lett· August 2006

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Development of N-2,4-pyrimidine-N-phenyl-N'-alkyl ureas as orally active inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 2.
Jennifer A Maier, Todd A Brugel, Michael P Clark, Mark Sabat, Adam Golebiowski, Richard L Walter

Bioorg Med Chem Lett· July 2006

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The development of monocyclic pyrazolone based cytokine synthesis inhibitors.
Adam Golebiowski, Jennifer A Townes, Matthew J Laufersweiler, Todd A Brugel, Michael P Clark, Richard L Walter

Bioorg Med Chem Lett· May 2005

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The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-alpha) production.
Steven K Laughlin, Michael P Clark, Jane F Djung, Adam Golebiowski, Todd A Brugel, Richard L Walter

Bioorg Med Chem Lett· May 2005

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The development of new bicyclic pyrazole-based cytokine synthesis inhibitors.
Jennifer A Townes, Adam Golebiowski, Michael P Clark, Matthew J Laufersweiler, Todd A Brugel, Richard L Walter

Bioorg Med Chem Lett· October 2004

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The development of novel inhibitors of tumor necrosis factor-alpha (TNF-alpha) production based on substituted [5,5]-bicyclic pyrazolones.
Matthew J Laufersweiler, Todd A Brugel, Michael P Clark, Adam Golebiowski, Roger G Bookland, Richard L Walter

Bioorg Med Chem Lett· August 2004

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Development of orally bioavailable bicyclic pyrazolones as inhibitors of tumor necrosis factor-alpha production.
Michael P Clark, Steven K Laughlin, Matthew J Laufersweiler, Roger G Bookland, Todd A Brugel, Rick L Walter

J Med Chem· May 2004

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Crystal structure of protein isoaspartyl methyltransferase: a catalyst for protein repair.
M M Skinner, J M Puvathingal, R L Walter, A M Friedman

Structure· November 2000

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Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex.
D J Thiel, M H le Du, R L Walter, A D'Arcy, C Chène

Structure· September 2000

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Purine nucleoside phosphorylase. 2. Catalytic mechanism.
M D Erion, J D Stoeckler, W C Guida, R L Walter, S E Ealick

Biochemistry· September 1997

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Analyzing power measurements for 209Bi(n,n) at 6 and 9 MeV and consistent dispersive optical-model analyses for n+209Bi and n+208Pb from -20 to +80 MeV.
GJ Weisel, W Tornow, CR Howell, PD Felsher, M Alohali, RL Walter

Phys Rev C Nucl Phys· November 1996

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Multiple wavelength anomalous diffraction (MAD) crystal structure of rusticyanin: a highly oxidizing cupredoxin with extreme acid stability.
R L Walter, S E Ealick, A M Friedman, R C Blake, P Proctor

J Mol Biol· November 1996

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