Publications by authors named "Rachel Klevit"

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Small heat shock protein HSPB5 uses disorder to bind zinc with high affinity.
Maria K Janowska, Vanesa Racigh, Christoper N Woods, María Silvina Fornasari, Rachel E Klevit

J Biol Chem· December 2025

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Mapping Hydrogen Migration Thresholds for Site-Specific HDX-MS.
Charles C Mundorff, Sarah Hadley, Lisa M Tuttle, Yuqi Shi, Graeme C McAlister, Rachel E Klevit

Mol Cell Proteomics· November 2025

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De Novo Design of Miniprotein Inhibitors of Bacterial Adhesins.
Adam Chazin-Gray, Tuscan Thompson, Edward Lopatto, Pearl Magala, Patrick Erickson, Rachel Klevit

Res Sq· November 2025

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Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference.
Kelli L Hvorecny, Gianluca Interlandi, Tim S Veth, Pavel Aprikian, Anna Manchenko, Rachel E Klevit

Nat Commun· November 2025

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Small heat shock protein HSPB5 uses disorder to bind zinc with high affinity.
Maria K Janowska, Vanesa Racigh, Christoper N Woods, María Silvina Fornasari, Rachel E Klevit

bioRxiv· October 2025

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Disorder with consequence: Phosphorylation sites in HSPB5 yield distinct structural outcomes.
Natalie L Stone, Maria K Janowska, Lucas Narisawa, Lisa M Tuttle, Lindsey D Ulmer, Rachel E Klevit

bioRxiv· October 2025

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Design of Miniprotein Inhibitors of Bacterial Adhesins.
Adam M Chazin-Gray, Tuscan R Thompson, Edward D B Lopatto, Pearl Magala, Patrick W Erickson, Rachel E Klevit

bioRxiv· August 2025

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Ultra-slow conformational dynamics and catch bond formation of a Bacterial Adhesin revealed by a single-domain variant of FimH.
Pearl Magala, Lisa M Tuttle, Gianluca Interlandi, Laura A Carlucci, Molly Y Mollica, Rachel E Klevit

bioRxiv· July 2025

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Activation mechanism of small heat shock protein HSPB5 revealed by disease-associated mutants.
Christopher N Woods, Maria K Janowska, Lindsey D Ulmer, Jasleen Kaur Sidhu, Natalie L Stone, Rachel E Klevit

Proc Natl Acad Sci U S A· May 2025

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Force transmission through the inner kinetochore is enhanced by centromeric DNA sequences.
Elise Miedlar, Grace E Hamilton, Samuel R Witus, Sara J Gonske, Michael Riffle, Rachel E Klevit

Elife· May 2025

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Force transmission through the inner kinetochore is enhanced by centromeric DNA sequences.
Elise Miedlar, Grace E Hamilton, Samuel R Witus, Sara Gonske, Michael Riffle, Rachel E Klevit

bioRxiv· April 2025

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A framework for automated multimodal HDX-MS analysis.
Lisa M Tuttle, Rachel E Klevit, Miklos Guttman

bioRxiv· March 2025

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Rigorous Analysis of Multimodal HDX-MS Spectra.
Lisa M Tuttle, Ellie I James, Florian Georgescauld, Thomas E Wales, David D Weis, Rachel E Klevit

J Am Soc Mass Spectrom· February 2025

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Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference.
Kelli L Hvorecny, Gianluca Interlandi, Tim S Veth, Pavel Aprikian, Anna Manchenko, Rachel E Klevit

bioRxiv· December 2024

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High-Performance Workflow for Identifying Site-Specific Crosslinks Originating from a Genetically Incorporated, Photoreactive Amino Acid.
Lindsey D Ulmer, Daniele Canzani, Christopher N Woods, Natalie L Stone, Maria K Janowska, Rachel E Klevit

J Proteome Res· August 2024

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HDXBoxeR: an R package for statistical analysis and visualization of multiple Hydrogen-Deuterium Exchange Mass-Spectrometry datasets of different protein states.
Maria K Janowska, Katherine Reiter, Pearl Magala, Miklos Guttman, Rachel E Klevit

Bioinformatics· August 2024

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The beauty and complexity of the small heat shock proteins: a report on the proceedings of the fourth workshop on small heat shock proteins.
Heath Ecroyd, Britta Bartelt-Kirbach, Anat Ben-Zvi, Raffaella Bonavita, Yevheniia Bushman, Rachel Klevit

Cell Stress Chaperones· November 2023

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Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair.
Meiling Wang, Wenjing Li, Nozomi Tomimatsu, Corey H Yu, Jae-Hoon Ji, Rachel E Klevit

Mol Cell· October 2023

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BRCA1/BARD1 intrinsically disordered regions facilitate chromatin recruitment and ubiquitylation.
Samuel R Witus, Lisa M Tuttle, Wenjing Li, Alex Zelter, Meiling Wang, Rachel E Klevit

EMBO J· August 2023

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Conservation of transcriptional regulation by BRCA1 and BARD1 in Caenorhabditis elegans.
Ishor Thapa, Russell Vahrenkamp, Samuel R Witus, Caitlin Lightle, Owen Falkenberg, Rachel E Klevit

Nucleic Acids Res· March 2023

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Disordered region encodes α-crystallin chaperone activity toward lens client γD-crystallin.
Christopher N Woods, Lindsey D Ulmer, Miklos Guttman, Matthew F Bush, Rachel E Klevit

Proc Natl Acad Sci U S A· February 2023

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Cullin-independent recognition of HHARI substrates by a dynamic RBR catalytic domain.
Katherine H Reiter, Alex Zelter, Maria K Janowska, Michael Riffle, Nicholas Shulman, Rachel E Klevit

Structure· September 2022

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Neutralizing Antibodies Against Allosteric Proteins: Insights From a Bacterial Adhesin.
Evgeni V Sokurenko, Veronika Tchesnokova, Gianluca Interlandi, Rachel Klevit, Wendy E Thomas

J Mol Biol· September 2022

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BRCA1/BARD1 is a nucleosome reader and writer.
Samuel R Witus, Weixing Zhao, Peter S Brzovic, Rachel E Klevit

Trends Biochem Sci· July 2022

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A native chemical chaperone in the human eye lens.
Eugene Serebryany, Sourav Chowdhury, Christopher N Woods, David C Thorn, Nicki E Watson, Rachel E Klevit

Elife· June 2022

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