Publications by authors named "Ramakrishna Edupuganti"

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Correction: Maternal Embryonic Leucine Zipper Kinase Is Associated with Metastasis in Triple-negative Breast Cancer.
Xuemei Xie, Gaurav B Chauhan, Ramakrishna Edupuganti, Takahiro Kogawa, Jihyun Park

Cancer Res Commun· January 2024

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Maternal Embryonic Leucine Zipper Kinase is Associated with Metastasis in Triple-negative Breast Cancer.
Xuemei Xie, Gaurav B Chauhan, Ramakrishna Edupuganti, Takahiro Kogawa, Jihyun Park

Cancer Res Commun· June 2023

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Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo.
Tamer S Kaoud, William H Johnson, Nancy D Ebelt, Andrea Piserchio, Diana Zamora-Olivares, Ramakrishna Edupuganti

Nat Commun· November 2019

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Computational and Experimental Studies of Inhibitor Design for Aldolase A.
Rui Qi, Brandon Walker, Zhifeng Jing, Maiya Yu, Gabriel Stancu, Ramakrishna Edupuganti

J Phys Chem B· July 2019

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Computational insights into the binding of IN17 inhibitors to MELK.
Matthew Harger, Ju-Hyeon Lee, Brandon Walker, Juliana M Taliaferro, Ramakrishna Edupuganti

J Mol Model· May 2019

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A c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib.
Nancy D Ebelt, Tamer S Kaoud, Ramakrishna Edupuganti, Sabrina Van Ravenstein, Kevin N Dalby

Oncotarget· December 2017

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Serotonin Analogues as Inhibitors of Breast Cancer Cell Growth.
Jiney Jose, Clint D J Tavares, Nancy D Ebelt, Alessia Lodi, Ramakrishna Edupuganti

ACS Med Chem Lett· October 2017

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Discovery of a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth.
Ramakrishna Edupuganti, Juliana M Taliaferro, Qiantao Wang, Xuemei Xie, Eun Jeong Cho

Bioorg Med Chem· May 2017

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Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target.
Geoffrey Grandjean, Petrus R de Jong, Brian James, Mei Yee Koh, Robert Lemos, Ramakrishna Edupuganti

Cancer Res· July 2016

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Synthesis and structural analyses of phenylethynyl-substituted tris(2-pyridylmethyl)amines and their copper(ii) complexes.
Jaebum Lim, Vincent M Lynch, Ramakrishna Edupuganti, Andrew Ellington, Eric V Anslyn

Dalton Trans· June 2016

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Using docking and alchemical free energy approach to determine the binding mechanism of eEF2K inhibitors and prioritizing the compound synthesis.
Qiantao Wang, Ramakrishna Edupuganti, Clint D J Tavares, Kevin N Dalby, Pengyu Ren

Front Mol Biosci· May 2015

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Mechanistic Studies on Covalent Assemblies of Metal-Mediated Hemi-Aminal Ethers.
Hyun Hwa Jo, Ramakrishna Edupuganti, Lei You, Kevin N Dalby, Eric V Anslyn

Chem Sci· January 2015

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Quantification of a Pharmacodynamic ERK End Point in Melanoma Cell Lysates: Toward Personalized Precision Medicine.
Mangalika Warthaka, Charles H Adelmann, Tamer S Kaoud, Ramakrishna Edupuganti, Chunli Yan

ACS Med Chem Lett· January 2015

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Reversible covalent inhibition of eEF-2K by carbonitriles.
Ashwini K Devkota, Ramakrishna Edupuganti, Chunli Yan, Yue Shi, Jiney Jose

Chembiochem· November 2014

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Synthesis and biological evaluation of pyrido[2,3-d]pyrimidine-2,4-dione derivatives as eEF-2K inhibitors.
Ramakrishna Edupuganti, Qiantao Wang, Clint D J Tavares, Catrina A Chitjian, James L Bachman

Bioorg Med Chem· September 2014

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High-throughput screens for eEF-2 kinase.
Ashwini K Devkota, Mangalika Warthaka, Ramakrishna Edupuganti, Clint D J Tavares, William H Johnson

J Biomol Screen· March 2014

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Exploring naphthyl-carbohydrazides as inhibitors of influenza A viruses.
Sanmitra Barman, Lei You, Ran Chen, Vlad Codrea, Grace Kago, Ramakrishna Edupuganti

Eur J Med Chem· January 2014

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Synthesis and applications of masked oxo-sulfinamides in asymmetric synthesis.
Ramakrishna Edupuganti, Franklin A Davis

Org Biomol Chem· July 2012

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Synthesis of 5-fluoro- and 5-hydroxymethanoprolines via lithiation of N-BOC-methanopyrrolidines. Constrained Cγ-exo and Cγ-endo Flp and Hyp conformer mimics.
Grant R Krow, Matthew D Shoulders, Ramakrishna Edupuganti, Deepa Gandla, Fang Yu

J Org Chem· June 2012

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