Publications by authors named "Rene St-Jacques"

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Design and synthesis of potent, isoxazole-containing renin inhibitors.
Pierre-André Fournier, Mélissa Arbour, Elizabeth Cauchon, Austin Chen, Amandine Chefson, René St-Jacques

Bioorg Med Chem Lett· April 2012

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3,4-Diarylpiperidines as potent renin inhibitors.
Patrick Lacombe, Mélissa Arbour, Renée Aspiotis, Elizabeth Cauchon, Austin Chen, René St-Jacques

Bioorg Med Chem Lett· March 2012

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Characterization of a stable, hypertensive rat model suitable for the consecutive evaluation of human renin inhibitors.
René St-Jacques, Sylvie Toulmond, Anick Auger, Christoph Binkert, Wanda Cromlish

J Renin Angiotensin Aldosterone Syst· September 2011

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Renin inhibitors for the treatment of hypertension: design and optimization of a novel series of pyridone-substituted piperidines.
Austin Chen, Louis-Charles Campeau, Elizabeth Cauchon, Amandine Chefson, Yves Ducharme, René St-Jacques

Bioorg Med Chem Lett· July 2011

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Renin inhibitors for the treatment of hypertension: design and optimization of a novel series of tertiary alcohol-bearing piperidines.
Austin Chen, Elizabeth Cauchon, Amandine Chefson, Sarah Dolman, Yves Ducharme, René St-Jacques

Bioorg Med Chem Lett· July 2011

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Pharmacological and genetic evidence that cathepsin B is not the physiological activator of rodent prorenin.
M David Percival, Sylvie Toulmond, Nathalie Coulombe, Wanda Cromlish, Sylvie Desmarais, René St-Jacques

Biol Chem· December 2010

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Cathepsin K null mice show reduced adiposity during the rapid accumulation of fat stores.
Marcella Funicello, Michela Novelli, Maurizio Ragni, Teresa Vottari, Cesare Cocuzza, Rene St-Jacques

PLoS One· August 2007

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The geminal dimethyl analogue of Flurbiprofen as a novel Abeta42 inhibitor and potential Alzheimer's disease modifying agent.
Nicholas Stock, Benito Munoz, Jonathan D J Wrigley, Mark S Shearman, Dirk Beher, René St-Jacques

Bioorg Med Chem Lett· April 2006

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Characterization of hypoxia-induced ventilatory depression in newborn piglets.
Rene St-Jacques, James J Filiano, Robert A Darnall, Walter M St-John

Exp Physiol· July 2003

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