Publications by authors named "Richard H Scheller"

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Correction: An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody-Drug Conjugate for the Treatment of Hormone Receptor-Positive Breast Cancer.
Sunil Bhakta, Lisa M Crocker, Yvonne Chen, Meredith Hazen, Melissa M Schutten, Richard H Scheller

Mol Cancer Ther· November 2019

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An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody-Drug Conjugate for the Treatment of Hormone Receptor-Positive Breast Cancer.
Sunil Bhakta, Lisa M Crocker, Yvonne Chen, Meredith Hazen, Melissa M Schutten, Richard H Scheller

Mol Cancer Ther· March 2018

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An improved and robust DNA immunization method to develop antibodies against extracellular loops of multi-transmembrane proteins.
Meredith Hazen, Sunil Bhakta, Rajesh Vij, Steven Randle, Dara Kallop, Richard H Scheller

MAbs· October 2014

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Site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity through linker and antibody engineering.
Thomas H Pillow, Janet Tien, Kathryn L Parsons-Reponte, Sunil Bhakta, Hao Li, Richard H Scheller

J Med Chem· October 2014

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In search of the molecular mechanism of intracellular membrane fusion and neurotransmitter release.
Richard H Scheller

Nat Med· October 2013

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Rac and Rab GTPases dual effector Nischarin regulates vesicle maturation to facilitate survival of intracellular bacteria.
Coenraad Kuijl, Manohar Pilli, Suresh K Alahari, Hans Janssen, Poh-Sim Khoo, Richard H Scheller

EMBO J· March 2013

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Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates.
Ben-Quan Shen, Keyang Xu, Luna Liu, Helga Raab, Sunil Bhakta, Richard H Scheller

Nat Biotechnol· January 2012

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Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome.
Christopher J Westlake, Lisa M Baye, Maxence V Nachury, Kevin J Wright, Karen E Ervin, Richard H Scheller

Proc Natl Acad Sci U S A· February 2011

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Engineered thio-trastuzumab-DM1 conjugate with an improved therapeutic index to target human epidermal growth factor receptor 2-positive breast cancer.
Jagath R Junutula, Kelly M Flagella, Richard A Graham, Kathryn L Parsons, Edward Ha, Richard H Scheller

Clin Cancer Res· October 2010

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Isolation and characterization of a Drosophila neuropeptide gene.
Richard H Scheller, John R Nambu

Neuron· November 2008

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Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index.
Jagath R Junutula, Helga Raab, Suzanna Clark, Sunil Bhakta, Douglas D Leipold, Richard H Scheller

Nat Biotechnol· August 2008

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Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs.
Jagath R Junutula, Sunil Bhakta, Helga Raab, Karen E Ervin, Charles Eigenbrot, Richard H Scheller

J Immunol Methods· March 2008

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Why Cabilly must stand.
Richard H Scheller

Nat Biotechnol· October 2007

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A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis.
Maxence V Nachury, Alexander V Loktev, Qihong Zhang, Christopher J Westlake, Johan Peränen, Richard H Scheller

Cell· June 2007

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Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene.
Christopher J Westlake, Jagath R Junutula, Glenn C Simon, Manohar Pilli, Rytis Prekeris, Richard H Scheller

Proc Natl Acad Sci U S A· January 2007

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SNAREs--engines for membrane fusion.
Reinhard Jahn, Richard H Scheller

Nat Rev Mol Cell Biol· September 2006

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Death-receptor activation halts clathrin-dependent endocytosis.
Cary D Austin, David A Lawrence, Andrew A Peden, Eugene E Varfolomeev, Klara Totpal, Richard H Scheller

Proc Natl Acad Sci U S A· July 2006

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Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody-drug conjugates.
Cary D Austin, Xiaohui Wen, Lewis Gazzard, Christopher Nelson, Richard H Scheller

Proc Natl Acad Sci U S A· December 2005

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Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase.
Rongsheng Jin, Jagath R Junutula, Hugo T Matern, Karen E Ervin, Richard H Scheller

EMBO J· June 2005

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Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin.
Cary D Austin, Ann M De Mazière, Paul I Pisacane, Suzanne M van Dijk, Charles Eigenbrot, Richard H Scheller

Mol Biol Cell· December 2004

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Molecular characterization of Rab11 interactions with members of the family of Rab11-interacting proteins.
Jagath R Junutula, Eric Schonteich, Gayle M Wilson, Andrew A Peden, Richard H Scheller

J Biol Chem· August 2004

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The RCP-Rab11 complex regulates endocytic protein sorting.
Andrew A Peden, Eric Schonteich, John Chun, Jagath R Junutula, Richard H Scheller

Mol Biol Cell· August 2004

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Rab14 is involved in membrane trafficking between the Golgi complex and endosomes.
Jagath R Junutula, Ann M De Maziére, Andrew A Peden, Karen E Ervin, Raj J Advani, Richard H Scheller

Mol Biol Cell· May 2004

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Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins.
Andrew A Peden, Viola Oorschot, Boris A Hesser, Cary D Austin, Richard H Scheller

J Cell Biol· March 2004

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Recordings from single neocortical nerve terminals reveal a nonselective cation channel activated by decreases in extracellular calcium.
Stephen M Smith, Jeremy B Bergsman, Nobutoshi C Harata, Richard H Scheller, Richard W Tsien

Neuron· January 2004

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