Publications by authors named "Cary D Austin"

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Induction of a distinct macrophage population and protection from lung injury and fibrosis by Notch2 blockade.
Mayra Cruz Tleugabulova, Sandra P Melo, Aaron Wong, Alexander Arlantico, Meizi Liu, Cary D Austin

Nat Commun· November 2024

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The effects of inhaled corticosteroids on healthy airways.
Emanuele Marchi, Timothy S C Hinks, Matthew Richardson, Latifa Khalfaoui, Fiona A Symon, Cary D Austin

Allergy· July 2024

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Obinutuzumab Effectively Depletes Key B-cell Subsets in Blood and Tissue in End-stage Renal Disease Patients.
Cary M Looney, Aaron Schroeder, Erica Tavares, Jay Garg, Thomas Schindler, Cary D Austin

Transplant Direct· February 2023

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Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis.
Joseph Chavarria-Smith, Cecilia P C Chiu, Janet K Jackman, Jianping Yin, Juan Zhang, Cary D Austin

Sci Transl Med· December 2022

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Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker-high and -low severe asthma.
Latifa Khalfaoui, Fiona A Symon, Simon Couillard, Beverley Hargadon, Rekha Chaudhuri, Cary D Austin

Allergy· October 2022

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Deletion of a previously uncharacterized lipoprotein lirL confers resistance to an inhibitor of type II signal peptidase in .
Ke-Jung Huang, Homer Pantua, Jingyu Diao, Elizabeth Skippington, Michael Volny, Cary D Austin

Proc Natl Acad Sci U S A· September 2022

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Steroid-induced fibroblast growth factors drive an epithelial-mesenchymal inflammatory axis in severe asthma.
Riccardo Guidi, Daqi Xu, David F Choy, Thirumalai R Ramalingam, Wyne P Lee, Cary D Austin

Sci Transl Med· April 2022

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Discovery of Inhibitors of the Lipopolysaccharide Transporter MsbA: From a Screening Hit to Potent Wild-Type Gram-Negative Activity.
Vishal A Verma, Lan Wang, Sharada S Labadie, Jun Liang, Benjamin D Sellers, Cary D Austin

J Med Chem· March 2022

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Inhibition of Escherichia coli Lipoprotein Diacylglyceryl Transferase Is Insensitive to Resistance Caused by Deletion of Braun's Lipoprotein.
Jingyu Diao, Rie Komura, Tatsuya Sano, Homer Pantua, Kelly M Storek, Cary D Austin

J Bacteriol· June 2021

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The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models.
Arna Katewa, Eric Suto, Jessica Hui, Jose Heredia, Jie Liang, Cary D Austin

PLoS One· April 2021

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A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment.
Alessia Balestrini, Victory Joseph, Michelle Dourado, Rebecca M Reese, Shannon D Shields, Cary D Austin

J Exp Med· April 2021

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A randomized, placebo-controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER).
Cary D Austin, Melissa Gonzalez Edick, Ronald E Ferrando, Margaret Solon, Miriam Baca

Clin Exp Allergy· December 2020

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Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer.
WeiYu Lin, Daqi Xu, Cary D Austin, Patrick Caplazi, Kate Senger

Front Immunol· October 2020

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Unstable Mechanisms of Resistance to Inhibitors of Escherichia coli Lipoprotein Signal Peptidase.
Homer Pantua, Elizabeth Skippington, Marie-Gabrielle Braun, Cameron L Noland, Jingyu Diao, Cary D Austin

mBio· September 2020

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The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells.
Cesar A Corzo, Eugene Varfolomeev, A Francesca Setiadi, Ross Francis, Sha Klabunde, Cary D Austin

Sci Signal· June 2020

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An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Henry R Maun, Janet K Jackman, David F Choy, Kelly M Loyet, Tracy L Staton, Cary D Austin

Cell· January 2020

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An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Henry R Maun, Janet K Jackman, David F Choy, Kelly M Loyet, Tracy L Staton, Cary D Austin

Cell· October 2019

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Airway pathological heterogeneity in asthma: Visualization of disease microclusters using topological data analysis.
Salman Siddiqui, Aarti Shikotra, Matthew Richardson, Emma Doran, David Choy, Cary D Austin

J Allergy Clin Immunol· November 2018

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Structural basis for dual-mode inhibition of the ABC transporter MsbA.
Hoangdung Ho, Anh Miu, Mary Kate Alexander, Natalie K Garcia, Angela Oh, Cary D Austin

Nature· May 2018

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NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus.
Hans D Brightbill, Eric Suto, Nicole Blaquiere, Nandhini Ramamoorthi, Swathi Sujatha-Bhaskar, Cary D Austin

Nat Commun· January 2018

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Host-derived fatty acids activate type VII secretion in .
Michael S Lopez, Irene S Tan, Donghong Yan, Jing Kang, Mark McCreary, Cary D Austin

Proc Natl Acad Sci U S A· October 2017

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The Ox40/Ox40 Ligand Pathway Promotes Pathogenic Th Cell Responses, Plasmablast Accumulation, and Lupus Nephritis in NZB/W F1 Mice.
Jonathan Sitrin, Eric Suto, Arthur Wuster, Jeffrey Eastham-Anderson, Jeong M Kim, Cary D Austin

J Immunol· August 2017

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Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFN-driven lupus nephritis.
Arna Katewa, Yugang Wang, Jason A Hackney, Tao Huang, Eric Suto, Cary D Austin

JCI Insight· April 2017

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De Novo Guanine Biosynthesis but Not the Riboswitch-Regulated Purine Salvage Pathway Is Required for Staphylococcus aureus Infection In Vivo.
Eric M Kofoed, Donghong Yan, Anand K Katakam, Mike Reichelt, Baiwei Lin, Cary D Austin

J Bacteriol· July 2016

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Depletion of major pathogenic cells in asthma by targeting CRTh2.
Tao Huang, Meredith Hazen, Yonglei Shang, Meijuan Zhou, Xiumin Wu, Cary D Austin

JCI Insight· May 2016

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