Publications by authors named "Richard Looby"

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Self-Delivering RNAi Compounds for Reduction of Hyperpigmentation.
Melissa Maxwell, Katherine Holton, Richard J Looby, Michael Byrne, James Cardia

Clin Cosmet Investig Dermatol· December 2024

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Preclinical evaluation of stereopure antisense oligonucleotides for allele-selective lowering of mutant .
Naoki Iwamoto, Yuanjing Liu, Maria Frank-Kamenetsky, Abbie Maguire, Wei Chou Tseng, Richard Looby

Mol Ther Nucleic Acids· September 2024

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Endogenous ADAR-mediated RNA editing in non-human primates using stereopure chemically modified oligonucleotides.
Prashant Monian, Chikdu Shivalila, Genliang Lu, Mamoru Shimizu, David Boulay, Richard Looby

Nat Biotechnol· July 2022

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Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNS.
Pachamuthu Kandasamy, Yuanjing Liu, Vincent Aduda, Sandheep Akare, Rowshon Alam, Richard Looby

Nucleic Acids Res· June 2022

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Stereochemistry Enhances Potency, Efficacy, and Durability of Antisense Oligonucleotides In Vitro and In Vivo in Multiple Species.
Michael Byrne, Vinod Vathipadiekal, Luciano Apponi, Naoki Iwamoto, Pachamuthu Kandasamy, Richard Looby

Transl Vis Sci Technol· January 2021

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Molecular imaging of oxidized collagen quantifies pulmonary and hepatic fibrogenesis.
Howard H Chen, Philip A Waghorn, Lan Wei, Luis F Tapias, Daniel T Schühle, Richard J Looby

JCI Insight· June 2017

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In vivo molecular imaging of thrombosis and thrombolysis using a fibrin-binding positron emission tomographic probe.
Ilknur Ay, Francesco Blasi, Tyson A Rietz, Nicholas J Rotile, Sreekanth Kura, Richard J Looby

Circ Cardiovasc Imaging· July 2014

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Effect of Chelate Type and Radioisotope on the Imaging Efficacy of 4 Fibrin-Specific PET Probes.
Francesco Blasi, Bruno L Oliveira, Tyson A Rietz, Nicholas J Rotile, Helen Day, Richard J Looby

J Nucl Med· July 2014

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Direct interaction between an allosteric agonist pepducin and the chemokine receptor CXCR4.
Jay M Janz, Yong Ren, Richard Looby, Manija A Kazmi, Pallavi Sachdev

J Am Chem Soc· October 2011

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Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells.
Boris Tchernychev, Yong Ren, Pallavi Sachdev, Jay M Janz, Lynn Haggis, Richard Looby

Proc Natl Acad Sci U S A· December 2010

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A lysine walk to high relaxivity collagen-targeted MRI contrast agents.
Peter Caravan, Biplab Das, Qing Deng, Stéphane Dumas, Vincent Jacques, Richard J Looby

Chem Commun (Camb)· January 2009

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EP-2104R: a fibrin-specific gadolinium-Based MRI contrast agent for detection of thrombus.
Kirsten Overoye-Chan, Steffi Koerner, Richard J Looby, Andrew F Kolodziej, Stephan G Zech

J Am Chem Soc· May 2008

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When are two waters worse than one? Doubling the hydration number of a Gd-DTPA derivative decreases relaxivity.
Peter Caravan, John C Amedio, Stephen U Dunham, Matthew T Greenfield, Normand J Cloutier, Richard J Looby

Chemistry· October 2005

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The interaction of MS-325 with human serum albumin and its effect on proton relaxation rates.
Peter Caravan, Normand J Cloutier, Matthew T Greenfield, Sarah A McDermid, Stephen U Dunham, Richard J Looby

J Am Chem Soc· March 2002

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