Publications by authors named "Richard Peck"

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CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trials.
Jan Rekowski, Christina Guo, Olga Solovyeva, Munyaradzi Dimairo, Mahtab Rouhifard, Richard Peck

EClinicalMedicine· January 2025

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SPIRIT-DEFINE explanation and elaboration: recommendations for enhancing quality and impact of early phase dose-finding clinical trials protocols.
Moreno Ursino, Guillermo Villacampa, Jan Rekowski, Munyaradzi Dimairo, Olga Solovyeva, Richard Peck

EClinicalMedicine· January 2025

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Beyond Population-Level Targets for Drug Concentrations: Precision Dosing Needs Individual-Level Targets that Include Superior Biomarkers of Drug Responses.
Thomas M Polasek, Richard W Peck

Clin Pharmacol Ther· September 2024

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Recent Advances Addressing the Challenges of Precision Dosing.
Iris K Minichmayr, Tomoyuki Mizuno, Srijib Goswami, Richard W Peck, Thomas M Polasek

Clin Pharmacol Ther· September 2024

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Using Machine Learning to Individualize Treatment Effect Estimation: Challenges and Opportunities.
Alicia Curth, Richard W Peck, Eoin McKinney, James Weatherall, Mihaela van der Schaar

Clin Pharmacol Ther· April 2024

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Development and application of neonatal physiology-based pharmacokinetic models of amikacin and fosfomycin to assess pharmacodynamic target attainment.
Christopher A Darlow, Neil Parrott, Richard W Peck, William Hope

CPT Pharmacometrics Syst Pharmacol· March 2024

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Ensuring Transparency and Quality of Clinical Trial Reporting in Clinical Pharmacology & Therapeutics: Prospective Trial Registration and Compliance with Reporting Guidelines Are Required for all Clinical Trials.
D Max Smith, Iris K Minichmayr, Joseph F Standing, Kathleen M Giacomini, Piet H van der Graaf, Richard W Peck

Clin Pharmacol Ther· December 2023

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Bridging the Worlds of Pharmacometrics and Machine Learning.
Kamilė Stankevičiūtė, Jean-Baptiste Woillard, Richard W Peck, Pierre Marquet, Mihaela van der Schaar

Clin Pharmacokinet· November 2023

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Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance.
Christina Yap, Jan Rekowski, Moreno Ursino, Olga Solovyeva, Dhrusti Patel, Richard Peck

BMJ· October 2023

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Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance.
Christina Yap, Olga Solovyeva, Johann de Bono, Jan Rekowski, Dhrusti Patel, Richard Peck

BMJ· October 2023

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Digital Therapeutics as a New Therapeutic Modality: A Review from the Perspective of Clinical Pharmacology.
Benjamin Ribba, Richard Peck, Lucy Hutchinson, Imein Bousnina, Dario Motti

Clin Pharmacol Ther· September 2023

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Synthetic Model Combination: A new machine-learning method for pharmacometric model ensembling.
Alexander Chan, Richard Peck, Megan Gibbs, Mihaela van der Schaar

CPT Pharmacometrics Syst Pharmacol· July 2023

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Artificial intelligence assessment of the potential of tocilizumab along with corticosteroids therapy for the management of COVID-19 evoked acute respiratory distress syndrome.
Cristina Segú-Vergés, Laura Artigas, Mireia Coma, Richard W Peck

PLoS One· February 2023

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Model enhanced reinforcement learning to enable precision dosing: A theoretical case study with dosing of propofol.
Benjamin Ribba, Dominic Stefan Bräm, Paul Gabriel Baverel, Richard Wilson Peck

CPT Pharmacometrics Syst Pharmacol· November 2022

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OXA-48-Like β-Lactamases: Global Epidemiology, Treatment Options, and Development Pipeline.
Sara E Boyd, Alison Holmes, Richard Peck, David M Livermore, William Hope

Antimicrob Agents Chemother· August 2022

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BIA 10-2474: Some Lessons are Clear but Important Questions Remain Unanswered.
Richard W Peck, Sarah A Holstein, Piet H van der Graaf

Clin Pharmacol Ther· February 2022

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Response to "Personalized Dosing = Approved Wide Dose Ranges + Dose Titration".
J Robert Powell, Jack Cook, Yaning Wang, Richard Peck, Daniel Weiner

Clin Pharmacol Ther· March 2021

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Drug Dosing Recommendations for All Patients: A Roadmap for Change.
J Robert Powell, Jack Cook, Yaning Wang, Richard Peck, Dan Weiner

Clin Pharmacol Ther· January 2021

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Precision Dosing: An Industry Perspective.
Richard W Peck

Clin Pharmacol Ther· January 2021

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Precision Dosing: The Clinical Pharmacology of Goldilocks.
Richard W Peck, Mohamed H Shahin, Alexander A Vinks

Clin Pharmacol Ther· January 2021

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A Real-World Evidence Framework for Optimizing Dosing in All Patients With COVID-19.
Richard W Peck, Daniel Weiner, Jack Cook, J Robert Powell

Clin Pharmacol Ther· November 2020

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Model-Informed Artificial Intelligence: Reinforcement Learning for Precision Dosing.
Benjamin Ribba, Sherri Dudal, Thierry Lavé, Richard W Peck

Clin Pharmacol Ther· April 2020

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Data Science in Clinical Pharmacology and Drug Development for Improving Health Outcomes in Patients.
Richard W Peck, Pratik Shah, Spiros Vamvakas, Piet H van der Graaf

Clin Pharmacol Ther· April 2020

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Schrödinger's pipeline and the outsourcing of pharmaceutical innovation.
Peter McMeekin, Dennis W Lendrem, B Clare Lendrem, Arthur G Pratt, Richard Peck

Drug Discov Today· March 2020

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Organs-on-Chips in Clinical Pharmacology: Putting the Patient Into the Center of Treatment Selection and Drug Development.
Richard W Peck, Christopher D Hinojosa, Geraldine A Hamilton

Clin Pharmacol Ther· January 2020

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