Publications by authors named "Richard Rutter"

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Probing Mitochondrial Permeability Transition Pore Activity in Nucleated Cells and Platelets by High-Throughput Screening Assays Suggests Involvement of Protein Phosphatase 2B in Mitochondrial Dynamics.
Mao Xiang Chen, Emma Ward, Matilde Caivano, Sandy Toh, Kirsten Searle, A Richard Rutter

Assay Drug Dev Technol· December 2018

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Response to Pick.
Vincent Jaquet, A Richard Rutter

Antioxid Redox Signal· November 2015

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Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor.
Kazufumi Hirano, Woei Shin Chen, Adeline L W Chueng, Angela A Dunne, Tamara Seredenina, A Richard Rutter

Antioxid Redox Signal· August 2015

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GSK356278, a potent, selective, brain-penetrant phosphodiesterase 4 inhibitor that demonstrates anxiolytic and cognition-enhancing effects without inducing side effects in preclinical species.
A Richard Rutter, Alessandro Poffe, Palmina Cavallini, T Gregg Davis, Jessica Schneck

J Pharmacol Exp Ther· July 2014

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Identification of a series of 1,3,4-oxadiazol-2-amines as potent alpha-7 agonists with efficacy in the novel object recognition model of cognition.
John Skidmore, Zeenat Atcha, Emmanuelle Boucherat, Laura Castelletti, Deborah W Chen, Richard Rutter

Bioorg Med Chem Lett· May 2012

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The discovery of 2-fluoro-N-(3-fluoro-4-(5-((4-morpholinobutyl)amino)-1,3,4-oxadiazol-2-yl)phenyl)benzamide, a full agonist of the alpha-7 nicotinic acetylcholine receptor showing efficacy in the novel object recognition model of cognition enhancement.
John Skidmore, Zeenat Atcha, Emmanuelle Boucherat, Laura Castelletti, Deborah W Chen, Richard Rutter

Bioorg Med Chem Lett· May 2012

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In vivo 5-HT(6) receptor occupancy by antipsychotic drugs in the rat brain.
Kazufumi Hirano, Kirsten L Searle, Shabina Nasir, Chiu-Cheong Aw, Edward R Browne, A Richard Rutter

Neurosci Lett· October 2011

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Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARγ partial agonist.
Mairi Sime, Amanda C Allan, Paul Chapman, Charlotte Fieldhouse, Gerard M P Giblin, Richard A Rutter

Bioorg Med Chem Lett· September 2011

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Procognitive 5-HT6 antagonists in the rat forced swimming test: potential therapeutic utility in mood disorders associated with Alzheimer's disease.
Kazufumi Hirano, Thomas M Piers, Kirsten L Searle, Neil D Miller, A Richard Rutter

Life Sci· April 2009

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Differential interaction of NMDA receptor subtypes with the post-synaptic density-95 family of membrane associated guanylate kinase proteins.
Sarah L Cousins, Michalis Papadakis, A Richard Rutter, F Anne Stephenson

J Neurochem· February 2008

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Evidence from gene knockout studies implicates Asc-1 as the primary transporter mediating d-serine reuptake in the mouse CNS.
A Richard Rutter, Rosa L Fradley, Elizabeth M Garrett, Kerry L Chapman, Jason M Lawrence

Eur J Neurosci· March 2007

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Functional mapping of the transient receptor potential vanilloid 1 intracellular binding site.
Daniel M Johnson, Elizabeth M Garrett, Richard Rutter, Timothy P Bonnert, Ying-Duo Gao

Mol Pharmacol· September 2006

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Functional characterisation of the S512Y mutant vanilloid human TRPV1 receptor.
Kathy G Sutton, Elizabeth M Garrett, A Richard Rutter, Timothy P Bonnert, Wolfgang Jarolimek

Br J Pharmacol· November 2005

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Heteromerization and colocalization of TrpV1 and TrpV2 in mammalian cell lines and rat dorsal root ganglia.
A Richard Rutter, Qing-Ping Ma, Mathew Leveridge, Timothy P Bonnert

Neuroreport· November 2005

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Discrete expression of TRPV2 within the hypothalamo-neurohypophysial system: Implications for regulatory activity within the hypothalamic-pituitary-adrenal axis.
Anna Wainwright, A Richard Rutter, Guy R Seabrook, Kathryn Reilly, Kevin R Oliver

J Comp Neurol· June 2004

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Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms.
David S Reynolds, Thomas W Rosahl, Jennifer Cirone, Gillian F O'Meara, Alison Haythornthwaite, A Richard Rutter

J Neurosci· September 2003

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Further characterization of the molecular interaction between PSD-95 and NMDA receptors: the effect of the NR1 splice variant and evidence for modulation of channel gating.
A Richard Rutter, Fiona M Freeman, F Anne Stephenson

J Neurochem· June 2002

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