Publications by authors named "Richard Saperstein"

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Discovery of cyclic guanidines as potent, orally active, human glucagon receptor antagonists.
Christopher Sinz, Jiang Chang, Ashley Rouse Lins, Ed Brady, Mari Candelore, Richard Saperstein

Bioorg Med Chem Lett· December 2011

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Discovery of N-aryl-2-acylindole human glucagon receptor antagonists.
Christopher Sinz, Amy Bittner, Ed Brady, Mari Candelore, Qing Dallas-Yang, Richard Saperstein

Bioorg Med Chem Lett· December 2011

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Discovery of novel, potent, selective, and orally active human glucagon receptor antagonists containing a pyrazole core.
Dong-Ming Shen, Edward J Brady, Mari R Candelore, Qing Dallas-Yang, Victor D-H Ding, Richard Saperstein

Bioorg Med Chem Lett· January 2011

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Discovery of potent, orally active benzimidazole glucagon receptor antagonists.
Ronald M Kim, Jiang Chang, Ashley R Lins, Ed Brady, Mari R Candelore, Richard Saperstein

Bioorg Med Chem Lett· July 2008

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Design and synthesis of conformationally constrained tri-substituted ureas as potent antagonists of the human glucagon receptor.
Rui Liang, Lauren Abrardo, Edward J Brady, Mari Rios Candelore, Victor Ding, Richard Saperstein

Bioorg Med Chem Lett· February 2007

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Discovery of novel, potent, and orally active spiro-urea human glucagon receptor antagonists.
Dong-Ming Shen, Fengqi Zhang, Edward J Brady, Mari Rios Candelore, Qing Dallas-Yang, Richard Saperstein

Bioorg Med Chem Lett· October 2005

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Discovery and investigation of a novel class of thiophene-derived antagonists of the human glucagon receptor.
Joseph L Duffy, Brian A Kirk, Zenon Konteatis, Elizabeth L Campbell, Rui Liang, Richard Saperstein

Bioorg Med Chem Lett· March 2005

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A novel glucagon receptor antagonist inhibits glucagon-mediated biological effects.
Sajjad A Qureshi, Mari Rios Candelore, Dan Xie, Xiaodong Yang, Laurie M Tota, Richard Saperstein

Diabetes· December 2004

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Hepatic glucagon receptor binding and glucose-lowering in vivo by peptidyl and non-peptidyl glucagon receptor antagonists.
Qing Dallas-Yang, Xiaolan Shen, Mathias Strowski, Edward Brady, Richard Saperstein

Eur J Pharmacol· October 2004

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A new class of glycogen phosphorylase inhibitors.
Zhijian Lu, Joann Bohn, Raynald Bergeron, Qiaolin Deng, Kenneth P Ellsworth, Richard Saperstein

Bioorg Med Chem Lett· November 2003

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