Publications by authors named "Richard Wooster"

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Inhaled delivery of a lipid nanoparticle encapsulated messenger RNA encoding a ciliary protein for the treatment of primary ciliary dyskinesia.
Caroline J Woo, Ayed Allawzi, Nicholas Clark, Neha Kaushal, Tim Efthymiou, Richard Wooster

Pulm Pharmacol Ther· August 2022

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The clinical progress of mRNA vaccines and immunotherapies.
Ann J Barbier, Allen Yujie Jiang, Peng Zhang, Richard Wooster, Daniel G Anderson

Nat Biotechnol· June 2022

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Novel Miniaturized Drug Conjugate Leverages HSP90-driven Tumor Accumulation to Overcome PI3K Inhibitor Delivery Challenges to Solid Tumors.
Samantha Perino, Benoit Moreau, Jessica Freda, Amanda Cirello, Brian H White, Richard Wooster

Mol Cancer Ther· August 2020

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Targeting the Somatostatin Receptor 2 with the Miniaturized Drug Conjugate, PEN-221: A Potent and Novel Therapeutic for the Treatment of Small Cell Lung Cancer.
Kerry A Whalen, Brian H White, James M Quinn, Kristina Kriksciukaite, Rossitza Alargova, Richard Wooster

Mol Cancer Ther· November 2019

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Discovery of an SSTR2-Targeting Maytansinoid Conjugate (PEN-221) with Potent Activity in Vitro and in Vivo.
Brian H White, Kerry Whalen, Kristina Kriksciukaite, Rossitza Alargova, Tsun Au Yeung, Richard Wooster

J Med Chem· March 2019

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Erratum to: Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer.
Zhi Hu, Jian-Hua Mao, Christina Curtis, Ge Huang, Shenda Gu, Richard Wooster

Breast Cancer Res· February 2017

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Cancer nanomedicine: progress, challenges and opportunities.
Jinjun Shi, Philip W Kantoff, Richard Wooster, Omid C Farokhzad

Nat Rev Cancer· January 2017

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Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer.
Zhi Hu, Jian-Hua Mao, Christina Curtis, Ge Huang, Shenda Gu, Richard Wooster

Breast Cancer Res· July 2016

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Combined phosphatase and tensin homolog (PTEN) loss and fatty acid synthase (FAS) overexpression worsens the prognosis of Chinese patients with hepatocellular carcinoma.
Xuehua Zhu, Xia Qin, Maogui Fei, Wenmin Hou, Joel Greshock, Richard Wooster

Int J Mol Sci· September 2015

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HES6 drives a critical AR transcriptional programme to induce castration-resistant prostate cancer through activation of an E2F1-mediated cell cycle network.
Antonio Ramos-Montoya, Alastair D Lamb, Roslin Russell, Thomas Carroll, Sarah Jurmeister, Richard F Wooster

EMBO Mol Med· May 2014

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Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells.
Julia Billiard, Jennifer B Dennison, Jacques Briand, Roland S Annan, Deping Chai, Richard F Wooster

Cancer Metab· September 2013

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Mitogen-activated protein kinase (MEK/ERK) inhibition sensitizes cancer cells to centromere-associated protein E inhibition.
Patrick A Mayes, Yan Y Degenhardt, Andrew Wood, Yana Toporovskya, Sharon J Diskin, Richard Wooster

Int J Cancer· February 2013

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Systematic analysis of genotype-specific drug responses in cancer.
Nayoung Kim, Ningning He, Changsik Kim, Fan Zhang, Yiling Lu, Richard Wooster

Int J Cancer· November 2012

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Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth.
A Pieter J van den Heuvel, Junping Jing, Richard F Wooster, Kurtis E Bachman

Cancer Biol Ther· October 2012

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Tumor-stroma relationships: who's the driver?
Richard F Wooster

Cell Cycle· May 2012

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Comprehensive predictive biomarker analysis for MEK inhibitor GSK1120212.
Junping Jing, Joel Greshock, Joanna Dawn Holbrook, Aidan Gilmartin, Xiping Zhang, Richard Wooster

Mol Cancer Ther· March 2012

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Subtype and pathway specific responses to anticancer compounds in breast cancer.
Laura M Heiser, Anguraj Sadanandam, Wen-Lin Kuo, Stephen C Benz, Theodore C Goldstein, Richard F Wooster

Proc Natl Acad Sci U S A· February 2012

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Pooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1).
Nancy Liu-Sullivan, Jianping Zhang, Amy Bakleh, John Marchica, Jinyu Li, Richard Wooster

Oncotarget· December 2011

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Mutation and copy number detection in human cancers using a custom genotyping assay.
Christopher Moy, Muhammad U Aziz, Joel Greshock, Stephen Szabo, Elizabeth McNeil, Richard Wooster

Genomics· October 2011

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High chromosome number in hematological cancer cell lines is a negative predictor of response to the inhibition of Aurora B and C by GSK1070916.
Christopher Moy, Catherine A Oleykowski, Ramona Plant, Joel Greshock, Junping Jing, Richard Wooster

J Transl Med· July 2011

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A tale of two subunits: how the neomorphic R132H IDH1 mutation enhances production of αHG.
Beth Pietrak, Huizhen Zhao, Hongwei Qi, Chad Quinn, Enoch Gao, Richard Wooster

Biochemistry· May 2011

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Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability.
Yan Degenhardt, Joel Greshock, Sylvie Laquerre, Aidan G Gilmartin, Junping Jing, Richard Wooster

Mol Cancer Ther· July 2010

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Catalogue, cause, complexity and cure; the many uses of cancer genome sequence.
Richard Wooster, Kurtis E Bachman

Curr Opin Genet Dev· June 2010

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Molecular target class is predictive of in vitro response profile.
Joel Greshock, Kurtis E Bachman, Yan Y Degenhardt, Junping Jing, Yuan H Wen, Richard Wooster

Cancer Res· May 2010

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Serial transcriptome analysis and cross-species integration identifies centromere-associated protein E as a novel neuroblastoma target.
Naomi J Balamuth, Andrew Wood, Qun Wang, Jayanti Jagannathan, Patrick Mayes, Richard Wooster

Cancer Res· April 2010

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