Publications by authors named "Rob H Stierum"

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Correction to: Toxicogenomics directory of chemically exposed human hepatocytes.
Marianna Grinberg, Regina M Stöber, Karolina Edlund, Eugen Rempel, Patricio Godoy, Rob H Stierum

Arch Toxicol· March 2022

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Toxicogenomics directory of chemically exposed human hepatocytes.
Marianna Grinberg, Regina M Stöber, Karolina Edlund, Eugen Rempel, Patricio Godoy, Rob H Stierum

Arch Toxicol· December 2014

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Unraveling toxicological mechanisms and predicting toxicity classes with gene dysregulation networks.
Tessa E Pronk, Eugene P van Someren, Rob H Stierum, Janine Ezendam, Jeroen L A Pennings

J Appl Toxicol· December 2013

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Delay and impairment in brain development and function in rat offspring after maternal exposure to methylmercury.
Marijana Radonjic, Natalie L M Cappaert, Erik F J de Vries, Celine E F de Esch, Frieke C Kuper, Rob H Stierum

Toxicol Sci· May 2013

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Next-generation text-mining mediated generation of chemical response-specific gene sets for interpretation of gene expression data.
Kristina M Hettne, André Boorsma, Dorien A M van Dartel, Jelle J Goeman, Esther de Jong, Rob H Stierum

BMC Med Genomics· January 2013

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'Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans.
Marlon J A Jetten, Stan Gaj, Ainhoa Ruiz-Aracama, Theo M de Kok, Joost H M van Delft, Rob H Stierum

Toxicol Appl Pharmacol· March 2012

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A dictionary to identify small molecules and drugs in free text.
Kristina M Hettne, Rob H Stierum, Martijn J Schuemie, Peter J M Hendriksen, Bob J A Schijvenaars

Bioinformatics· November 2009

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A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo.
Anne S Kienhuis, Marcel C G van de Poll, Cornelis H C Dejong, Ralph Gottschalk, Marcel van Herwijnen, Rob H Stierum

Toxicol In Vitro· September 2009

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Parallelogram approach using rat-human in vitro and rat in vivo toxicogenomics predicts acetaminophen-induced hepatotoxicity in humans.
Anne S Kienhuis, Marcel C G van de Poll, Heleen Wortelboer, Marcel van Herwijnen, Ralph Gottschalk, Rob H Stierum

Toxicol Sci· February 2009

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The contact allergen dinitrochlorobenzene (DNCB) and respiratory allergy in the Th2-prone Brown Norway rat.
C Frieke Kuper, Rob H Stierum, Andre Boorsma, Marcel A Schijf, Menk Prinsen

Toxicology· April 2008

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Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis.
Ashwin A Dihal, Hester van der Woude, Peter J M Hendriksen, Halima Charif, Lennard J Dekker, Rob H Stierum

Proteomics· January 2008

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Transcriptomics analysis of interactive effects of benzene, trichloroethylene and methyl mercury within binary and ternary mixtures on the liver and kidney following subchronic exposure in the rat.
Peter J M Hendriksen, Andreas P Freidig, Diana Jonker, Uwe Thissen, Jan J P Bogaards, Rob H Stierum

Toxicol Appl Pharmacol· December 2007

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Pathway and single gene analyses of inhibited Caco-2 differentiation by ascorbate-stabilized quercetin suggest enhancement of cellular processes associated with development of colon cancer.
Ashwin A Dihal, Chantal Tilburgs, Marjan J van Erk, Ivonne M C M Rietjens, Ruud A Woutersen, Rob H Stierum

Mol Nutr Food Res· August 2007

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The introduction of toxicogenomics; potential new markers of hepatotoxicity.
Wilbert H M Heijne, Rob H Stierum, Winfried R Leeman, Ben van Ommen

Cancer Biomark· February 2007

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Comparison of coumarin-induced toxicity between sandwich-cultured primary rat hepatocytes and rats in vivo: a toxicogenomics approach.
Anne S Kienhuis, Heleen M Wortelboer, Jean-Christophe Hoflack, Edwin J Moonen, Jos C S Kleinjans, Rob H Stierum

Drug Metab Dispos· December 2006

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Quercetin, but not its glycosidated conjugate rutin, inhibits azoxymethane-induced colorectal carcinogenesis in F344 rats.
Ashwin A Dihal, Vincent C J de Boer, Hester van der Woude, Chantal Tilburgs, Joost P Bruijntjes, Rob H Stierum

J Nutr· November 2006

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Modulatory effects of quercetin on proliferation and differentiation of the human colorectal cell line Caco-2.
Ashwin A Dihal, Ruud A Woutersen, Ben van Ommen, Ivonne M C M Rietjens, Rob H Stierum

Cancer Lett· July 2006

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Systems toxicology: applications of toxicogenomics, transcriptomics, proteomics and metabolomics in toxicology.
Wilbert H M Heijne, Anne S Kienhuis, Ben van Ommen, Rob H Stierum, John P Groten

Expert Rev Proteomics· October 2005

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Toxicogenomic analysis of gene expression changes in rat liver after a 28-day oral benzene exposure.
Wilbert H M Heijne, Diana Jonker, Rob H Stierum, Ben van Ommen, John P Groten

Mutat Res· August 2005

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Integrated assessment by multiple gene expression analysis of quercetin bioactivity on anticancer-related mechanisms in colon cancer cells in vitro.
Marjan J van Erk, Paul Roepman, Ted R van der Lende, Rob H Stierum, Jac M M J G Aarts

Eur J Nutr· March 2005

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Toxicology of chemical mixtures: a challenging quest along empirical sciences.
John P Groten, Wilbert H M Heijne, Rob H Stierum, Andreas P Freidig, Victor J Feron

Environ Toxicol Pharmacol· December 2004

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Bromobenzene-induced hepatotoxicity at the transcriptome level.
Wilbert H M Heijne, Angela L Slitt, Peter J van Bladeren, John P Groten, Curtis D Klaassen, Rob H Stierum

Toxicol Sci· June 2004

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Effect of thiabendazole on some rat hepatic xenobiotic metabolising enzymes.
Roger J Price, Mary P Scott, David G Walters, Rob H Stierum, John P Groten

Food Chem Toxicol· June 2004

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Toxicogenomics of bromobenzene hepatotoxicity: a combined transcriptomics and proteomics approach.
Wilbert H M Heijne, Rob H Stierum, Monique Slijper, Peter J van Bladeren, Ben van Ommen

Biochem Pharmacol· March 2003

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