Publications by authors named "Robert Bailer"

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Safety and pharmacokinetics of N6LS, a broadly neutralising monoclonal antibody for HIV: a phase 1, open-label, dose-escalation study in healthy adults.
Richard L Wu, Katherine V Houser, Martin R Gaudinski, Alicia T Widge, Seemal F Awan, Robert T Bailer

Lancet HIV· July 2025

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Phase 1 trial evaluating safety and pharmacokinetics of HIV-1 broadly neutralizing mAbs 10E8VLS and VRC07-523LS.
Seemal F Awan, Amarendra Pegu, Larisa Strom, Cristina A Carter, Cynthia S Hendel, Robert T Bailer

JCI Insight· April 2024

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Heterologous cAd3-Ebola and MVA-EbolaZ vaccines are safe and immunogenic in US and Uganda phase 1/1b trials.
Myra Happe, Amelia R Hofstetter, Jing Wang, Galina V Yamshchikov, LaSonji A Holman, Robert T Bailer

NPJ Vaccines· March 2024

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Safety and immunogenicity of a ferritin nanoparticle H2 influenza vaccine in healthy adults: a phase 1 trial.
Katherine V Houser, Grace L Chen, Cristina Carter, Michelle C Crank, Thuy A Nguyen, Robert T Bailer

Nat Med· February 2022

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Safety, tolerability, and immunogenicity of the respiratory syncytial virus prefusion F subunit vaccine DS-Cav1: a phase 1, randomised, open-label, dose-escalation clinical trial.
Tracy J Ruckwardt, Kaitlyn M Morabito, Emily Phung, Michelle C Crank, Pamela J Costner, Robert Bailer

Lancet Respir Med· October 2021

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Safety, Tolerability, and Pharmacokinetics of the Broadly Neutralizing Human Immunodeficiency Virus (HIV)-1 Monoclonal Antibody VRC01 in HIV-Exposed Newborn Infants.
Coleen K Cunningham, Elizabeth J McFarland, R Leavitt Morrison, Edmund V Capparelli, Jeffrey T Safrit, Robert T Bailer

J Infect Dis· July 2020

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Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound.
Evan M Cale, Hongjun Bai, Meera Bose, Michael A Messina, Donn J Colby, Robert T Bailer

J Clin Invest· June 2020

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Brief Report: Prediction of Serum HIV-1 Neutralization Titers After Passive Administration of VRC01.
Yunda Huang, Yuanyuan Zhang, Robert Bailer, Nicole Grunenberg, Lindsay N Carpp

J Acquir Immune Defic Syndr· April 2020

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Effect of a Chikungunya Virus-Like Particle Vaccine on Safety and Tolerability Outcomes: A Randomized Clinical Trial.
Grace L Chen, Emily E Coates, Sarah H Plummer, Cristina A Carter, Nina Berkowitz, Robert T Bailer

JAMA· April 2020

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Safety and immunogenicity of investigational seasonal influenza hemagglutinin DNA vaccine followed by trivalent inactivated vaccine administered intradermally or intramuscularly in healthy adults: An open-label randomized phase 1 clinical trial.
Cristina Carter, Katherine V Houser, Galina V Yamshchikov, Abbie R Bellamy, Jeanine May, Robert T Bailer

PLoS One· March 2020

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Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability.
Viktoriya Dubrovskaya, Karen Tran, Gabriel Ozorowski, Javier Guenaga, Richard Wilson, Robert T Bailer

Immunity· November 2019

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Safety and pharmacokinetics of broadly neutralising human monoclonal antibody VRC07-523LS in healthy adults: a phase 1 dose-escalation clinical trial.
Martin R Gaudinski, Katherine V Houser, Nicole A Doria-Rose, Grace L Chen, Ro Shauna S Rothwell, Robert T Bailer

Lancet HIV· October 2019

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Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields.
Jason Gorman, Rosemarie D Mason, Leonard Nettey, Nicole Cavett, Gwo-Yu Chuang, Robert T Bailer

Immunity· October 2019

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Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Rui Kong, Hongying Duan, Zizhang Sheng, Kai Xu, Priyamvada Acharya, Robert T Bailer

Cell· July 2019

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Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Till Schoofs, Christopher O Barnes, Nina Suh-Toma, Jovana Golijanin, Philipp Schommers, Robert T Bailer

Immunity· June 2019

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Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial.
Trevor A Crowell, Donn J Colby, Suteeraporn Pinyakorn, Carlo Sacdalan, Amélie Pagliuzza, Robert T Bailer

Lancet HIV· May 2019

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DNA vaccine priming for seasonal influenza vaccine in children and adolescents 6 to 17 years of age: A phase 1 randomized clinical trial.
Katherine V Houser, Galina V Yamshchikov, Abbie R Bellamy, Jeanine May, Mary E Enama, Robert T Bailer

PLoS One· April 2019

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Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine.
Kenta Matsuda, Jinghe Huang, Tongqing Zhou, Zizhang Sheng, Byong H Kang, Robert T Bailer

Sci Immunol· April 2019

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Safety, tolerability, pharmacokinetics, and immunogenicity of the therapeutic monoclonal antibody mAb114 targeting Ebola virus glycoprotein (VRC 608): an open-label phase 1 study.
Martin R Gaudinski, Emily E Coates, Laura Novik, Alicia Widge, Katherine V Houser, Robert T Bailer

Lancet· March 2019

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Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Shelly J Krebs, Young D Kwon, Chaim A Schramm, William H Law, Gina Donofrio, Robert T Bailer

Immunity· March 2019

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Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition.
Gwo-Yu Chuang, Jing Zhou, Priyamvada Acharya, Reda Rawi, Chen-Hsiang Shen, Robert T Bailer

Structure· January 2019

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Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Yen-Ting Lai, Tao Wang, Sijy O'Dell, Mark K Louder, Arne Schön, Robert T Bailer

Nat Commun· January 2019

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Randomized Clinical Trial to Assess the Impact of the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01 on HIV-1 Persistence in Individuals on Effective ART.
Sharon A Riddler, Lu Zheng, Christine M Durand, Justin Ritz, Richard A Koup, Robert T Bailer

Open Forum Infect Dis· October 2018

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Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Kai Xu, Priyamvada Acharya, Rui Kong, Cheng Cheng, Gwo-Yu Chuang, Robert T Bailer

Nat Med· June 2018

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A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.
Tongqing Zhou, Anqi Zheng, Ulrich Baxa, Gwo-Yu Chuang, Ivelin S Georgiev, Robert T Bailer

Immunity· March 2018

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