Publications by authors named "Robert Kyne"

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The scheduling of adolescence with Netrin-1 and UNC5C.
Daniel Hoops, Robert Kyne, Samer Salameh, Del MacGowan, Radu Gabriel Avramescu

Elife· July 2024

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The scheduling of adolescence with Netrin-1 and UNC5C.
Daniel Hoops, Robert F Kyne, Samer Salameh, Del MacGowan, Radu G Avramescu

bioRxiv· April 2024

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Long-term consequences of peri-adolescent social isolation on social preference, anxiety-like behaviour, and vasopressin neural circuitry of male and female rats.
Brianna L Kinley, Robert F Kyne, Tamijah S Lawton-Stone, Deena M Walker, Matthew J Paul

Eur J Neurosci· December 2021

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Photoperiod regulates hypothalamic miR-155 gene expression in female, but not male, Siberian hamsters (Phodopus sungorus).
Surbhi, Kelcie C Schatz, Robert F Kyne, Randy J Nelson, Matthew J Paul

Behav Neurosci· April 2019

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Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist.
Mark E Schnute, Mattias Wennerstål, Jennifer Alley, Martin Bengtsson, James R Blinn, Robert E Kyne

J Med Chem· December 2018

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Investigation of social, affective, and locomotor behavior of adolescent Brattleboro rats reveals a link between vasopressin's actions on arousal and social behavior.
Kelcie C Schatz, Robert F Kyne, Stephanie L Parmeter, Matthew J Paul

Horm Behav· November 2018

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Correction to Synthetic Approaches to the New Drugs Approved During 2015.
Andrew C Flick, Hong X Ding, Carolyn A Leverett, Robert E Kyne, Kevin K-C Liu

J Med Chem· October 2017

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Synthetic Approaches to the New Drugs Approved During 2015.
Andrew C Flick, Hong X Ding, Carolyn A Leverett, Robert E Kyne, Kevin K-C Liu

J Med Chem· August 2017

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Covalent Enzyme Inhibition through Fluorosulfate Modification of a Noncatalytic Serine Residue.
Olugbeminiyi O Fadeyi, Lise R Hoth, Chulho Choi, Xidong Feng, Ariamala Gopalsamy, Robert E Kyne

ACS Chem Biol· August 2017

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Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA).
Ariamala Gopalsamy, Arjun Narayanan, Shenping Liu, Mihir D Parikh, Robert E Kyne

J Med Chem· April 2017

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Selectivity Determination of a Small Molecule Chemical Probe Using Protein Microarray and Affinity Capture Techniques.
Erik C Hett, Robert E Kyne, Ariamala Gopalsamy, Michael A Tones, Hua Xu

ACS Comb Sci· October 2016

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Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis.
Olugbeminiyi Fadeyi, Mihir D Parikh, Ming Z Chen, Robert E Kyne, Alexandria P Taylor

Chembiochem· October 2016

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Cellular thermal shift and clickable chemical probe assays for the determination of drug-target engagement in live cells.
Hua Xu, Ariamala Gopalsamy, Erik C Hett, Shores Salter, Ann Aulabaugh, Robert E Kyne

Org Biomol Chem· July 2016

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Synthetic approaches to the 2014 new drugs.
Andrew C Flick, Hong X Ding, Carolyn A Leverett, Robert E Kyne, Kevin K-C Liu

Bioorg Med Chem· May 2016

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A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS.
Hua Xu, Erik C Hett, Ariamala Gopalsamy, Mihir D Parikh, Kieran F Geoghegan, Robert E Kyne

Mol Biosyst· October 2015

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Synthetic approaches to the 2013 new drugs.
Hong X Ding, Carolyn A Leverett, Robert E Kyne, Kevin K-C Liu, Sarah J Fink

Bioorg Med Chem· May 2015

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Rational targeting of active-site tyrosine residues using sulfonyl fluoride probes.
Erik C Hett, Hua Xu, Kieran F Geoghegan, Ariamala Gopalsamy, Robert E Kyne

ACS Chem Biol· April 2015

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Synthesis of pyrazoles from 1,3-diols via hydrogen transfer catalysis.
Daniel C Schmitt, Alexandria P Taylor, Andrew C Flick, Robert E Kyne

Org Lett· March 2015

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Synthetic approaches to the 2012 new drugs.
Hong X Ding, Carolyn A Leverett, Robert E Kyne, Kevin K-C Liu, Subas M Sakya

Bioorg Med Chem· April 2014

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Catalytic enantioselective allyl-allyl cross-coupling with a borylated allylboronate.
Hai Le, Robert E Kyne, Laura A Brozek, James P Morken

Org Lett· April 2013

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Enantioselective construction of all-carbon quaternary centers by branch-selective Pd-catalyzed allyl-allyl cross-coupling.
Ping Zhang, Hai Le, Robert E Kyne, James P Morken

J Am Chem Soc· June 2011

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Allylation of nitrosobenzene with pinacol allylboronates. A regioselective complement to peroxide oxidation.
Robert E Kyne, Michael C Ryan, Laura T Kliman, James P Morken

Org Lett· September 2010

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Intramolecular thermal allenyne [2 + 2] cycloadditions; facile construction of the 5-6-4 ring core of sterpurene.
Timo V Ovaska, Robert E Kyne

Tetrahedron Lett· January 2008

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Synthesis of seven-membered carbocyclic rings via a microwave-assisted tandem oxyanionic 5-exo dig cyclization-claisen rearrangement process.
Xin Li, Robert E Kyne, Timo V Ovaska

J Org Chem· August 2007

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Progress toward the total synthesis of frondosin C.
Xin Li, Robert E Kyne, Timo V Ovaska

Org Lett· October 2006

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