Publications by authors named "Robert Mathvink"

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Discovery of a 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) inhibitor of c-Met kinase for the treatment of cancer.
Jason D Katz, James P Jewell, David J Guerin, Jongwon Lim, Christopher J Dinsmore, Robert Mathvink

J Med Chem· June 2011

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Imidazopiperidine amides as dipeptidyl peptidase IV inhibitors for the treatment of diabetes.
Ping Chen, Charles G Caldwell, Robert J Mathvink, Barbara Leiting, Frank Marsilio

Bioorg Med Chem Lett· November 2007

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Discovery of potent, selective, and orally bioavailable oxadiazole-based dipeptidyl peptidase IV inhibitors.
Jinyou Xu, Lan Wei, Robert J Mathvink, Scott D Edmondson, George J Eiermann

Bioorg Med Chem Lett· October 2006

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(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
Scott D Edmondson, Anthony Mastracchio, Robert J Mathvink, Jiafang He, Bart Harper

J Med Chem· June 2006

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Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitors.
Jinyou Xu, Lan Wei, Robert Mathvink, Scott D Edmondson, Anthony Mastracchio

Bioorg Med Chem Lett· March 2006

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Discovery of potent and selective phenylalanine based dipeptidyl peptidase IV inhibitors.
Jinyou Xu, Lan Wei, Robert Mathvink, Jiafang He, You-Jung Park

Bioorg Med Chem Lett· May 2005

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The pharmacokinetics of a thiazole benzenesulfonamide beta 3-adrenergic receptor agonist and its analogs in rats, dogs, and monkeys: improving oral bioavailability.
Ralph A Stearns, Randy R Miller, Wei Tang, Gloria Y Kwei, Frank S Tang, Robert J Mathvink

Drug Metab Dispos· July 2002

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Metabolism of a thiazole benzenesulfonamide derivative, a potent and elective agonist of the human beta3-adrenergic receptor, in rats: identification of a novel isethionic acid conjugate.
Wei Tang, Ralph A Stearns, Randall R Miller, Jason S Ngui, Robert J Mathvink

Drug Metab Dispos· July 2002

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