Publications by authors named "Roberta Cozzi"

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Bactericidal human monoclonal antibody 1B1 shows specificity for meningococcal factor H binding protein variant 2 and displaces human factor H.
Daniele Veggi, Chelsy C Chesterman, Laura Santini, Ying Huang, Nicola Pacchiani, Roberta Cozzi

FASEB Bioadv· August 2024

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Computational structure-based approach to study chimeric antigens using a new protein scaffold displaying foreign epitopes.
Luigia Cappelli, Paolo Cinelli, Andrea Perrotta, Daniele Veggi, Martina Audagnotto, Roberta Cozzi

FASEB J· January 2024

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Author Correction: Proof of concept for a single-dose Group B Streptococcus vaccine based on capsular polysaccharide conjugated to Qβ virus-like particles.
Filippo Carboni, Roberta Cozzi, Giacomo Romagnoli, Giovanna Tuscano, Cristiana Balocchi

NPJ Vaccines· January 2024

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Proof of concept for a single-dose Group B Streptococcus vaccine based on capsular polysaccharide conjugated to Qβ virus-like particles.
Filippo Carboni, Roberta Cozzi, Giacomo Romagnoli, Giovanna Tuscano, Cristiana Balocchi

NPJ Vaccines· October 2023

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Self-assembling protein nanoparticles and virus like particles correctly display β-barrel from meningococcal factor H-binding protein through genetic fusion.
Luigia Cappelli, Paolo Cinelli, Fabiola Giusti, Ilaria Ferlenghi, Sabrina Utrio-Lanfaloni, Roberta Cozzi

PLoS One· September 2022

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4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp.
Daniele Veggi, Federica Bianchi, Laura Santini, Paola Lo Surdo, Chelsy C Chesterman, Roberta Cozzi

PLoS Pathog· October 2020

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Cocrystal structure of meningococcal factor H binding protein variant 3 reveals a new crossprotective epitope recognized by human mAb 1E6.
Federica Bianchi, Daniele Veggi, Laura Santini, Francesca Buricchi, Erika Bartolini, Roberta Cozzi

FASEB J· November 2019

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Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody.
Martina Maritan, Daniele Veggi, Roberta Cozzi, Lucia Dello Iacono, Erika Bartolini

PLoS One· January 2019

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Crystal structures of human Fabs targeting the Bexsero meningococcal vaccine antigen NHBA.
Martina Maritan, Roberta Cozzi, Paola Lo Surdo, Daniele Veggi, Matthew James Bottomley

Acta Crystallogr F Struct Biol Commun· June 2017

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An Innovative Pseudotypes-Based Enzyme-Linked Lectin Assay for the Measurement of Functional Anti-Neuraminidase Antibodies.
Marua Prevato, Roberta Cozzi, Alfredo Pezzicoli, Anna Rita Taddei, Ilaria Ferlenghi

PLoS One· May 2016

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Expression and Characterization of Recombinant, Tetrameric and Enzymatically Active Influenza Neuraminidase for the Setup of an Enzyme-Linked Lectin-Based Assay.
Marua Prevato, Ilaria Ferlenghi, Alessandra Bonci, Yasushi Uematsu, Giulia Anselmi, Roberta Cozzi

PLoS One· May 2016

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Crystal structure of FhuD at 1.6 Å resolution: a ferrichrome-binding protein from the animal and human pathogen Staphylococcus pseudintermedius.
Francesca Abate, Roberta Cozzi, Martina Maritan, Paola Lo Surdo, Domenico Maione

Acta Crystallogr F Struct Biol Commun· March 2016

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Structure and assembly of group B streptococcus pilus 2b backbone protein.
Roberta Cozzi, Enrico Malito, Maddalena Lazzarin, Annalisa Nuccitelli, Andrea Castagnetti

PLoS One· February 2016

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Noncanonical sortase-mediated assembly of pilus type 2b in group B Streptococcus.
Maddalena Lazzarin, Roberta Cozzi, Enrico Malito, Manuele Martinelli, Mariapina D'Onofrio

FASEB J· November 2015

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Protectome analysis: a new selective bioinformatics tool for bacterial vaccine candidate discovery.
Emrah Altindis, Roberta Cozzi, Benedetta Di Palo, Francesca Necchi, Ravi P Mishra

Mol Cell Proteomics· February 2015

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Apo, Zn2+-bound and Mn2+-bound structures reveal ligand-binding properties of SitA from the pathogen Staphylococcus pseudintermedius.
Francesca Abate, Enrico Malito, Roberta Cozzi, Paola Lo Surdo, Domenico Maione

Biosci Rep· November 2014

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Structural vaccinology: a three-dimensional view for vaccine development.
Roberta Cozzi, Maria Scarselli, Ilaria Ferlenghi

Curr Top Med Chem· June 2014

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Understanding the molecular determinants driving the immunological specificity of the protective pilus 2a backbone protein of group B streptococcus.
Annalisa Nuccitelli, C Daniela Rinaudo, Barbara Brogioni, Roberta Cozzi, Mario Ferrer-Navarro

PLoS Comput Biol· January 2014

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Group B Streptococcus pilus sortase regulation: a single mutation in the lid region induces pilin protein polymerization in vitro.
Roberta Cozzi, Francesca Zerbini, Michael Assfalg, Mariapina D'Onofrio, Massimiliano Biagini

FASEB J· August 2013

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Structural basis for group B streptococcus pilus 1 sortases C regulation and specificity.
Roberta Cozzi, Daniil Prigozhin, Roberto Rosini, Francesca Abate, Matthew J Bottomley

PLoS One· July 2013

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New insights into the role of the glutamic acid of the E-box motif in group B Streptococcus pilus 2a assembly.
Roberta Cozzi, Annalisa Nuccitelli, Mariapina D'Onofrio, Francesca Necchi, Roberto Rosini

FASEB J· May 2012

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Sortase A substrate specificity in GBS pilus 2a cell wall anchoring.
Francesca Necchi, Vincenzo Nardi-Dei, Massimiliano Biagini, Michael Assfalg, Annalisa Nuccitelli, Roberta Cozzi

PLoS One· February 2012

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Structure analysis and site-directed mutagenesis of defined key residues and motives for pilus-related sortase C1 in group B Streptococcus.
Roberta Cozzi, Enrico Malito, Annalisa Nuccitelli, Mariapina D'Onofrio, Manuele Martinelli

FASEB J· June 2011

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Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections.
Annalisa Nuccitelli, Roberta Cozzi, Louise J Gourlay, Danilo Donnarumma, Francesca Necchi

Proc Natl Acad Sci U S A· June 2011

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Toll-like receptor 2 dependent immunogenicity of glycoconjugate vaccines containing chemically derived zwitterionic polysaccharides.
Simona Gallorini, Francesco Berti, Giuseppe Mancuso, Roberta Cozzi, Marco Tortoli

Proc Natl Acad Sci U S A· October 2009

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