Publications by authors named "Robin A Carr"

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Application of fragment-based lead generation to the discovery of novel, cyclic amidine beta-secretase inhibitors with nanomolar potency, cellular activity, and high ligand efficiency.
Philip D Edwards, Jeffrey S Albert, Mark Sylvester, David Aharony, Donald Andisik, Robin A Carr

J Med Chem· November 2007

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Identification of inhibitors of protein kinase B using fragment-based lead discovery.
Gordon Saxty, Steven J Woodhead, Valerio Berdini, Thomas G Davies, Marcel L Verdonk, Robin A Carr

J Med Chem· May 2007

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Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase.
Miles Congreve, David Aharony, Jeffrey Albert, Owen Callaghan, James Campbell, Robin A E Carr

J Med Chem· March 2007

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Fragment-based lead discovery: leads by design.
Robin A E Carr, Miles Congreve, Christopher W Murray, David C Rees

Drug Discov Today· July 2005

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Identification of novel p38alpha MAP kinase inhibitors using fragment-based lead generation.
Adrian L Gill, Martyn Frederickson, Anne Cleasby, Steven J Woodhead, Maria G Carr, Robin A E Carr

J Med Chem· January 2005

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