Publications by authors named "Roger Brideau"

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Structure based design of an in vivo active hydroxamic acid inhibitor of P. aeruginosa LpxC.
Joseph S Warmus, Cheryl L Quinn, Clarke Taylor, Sean T Murphy, Timothy A Johnson, Roger Brideau

Bioorg Med Chem Lett· April 2012

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Synthesis of 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamides with broad-spectrum human herpesvirus polymerase inhibition.
Mark E Schnute, Roger J Brideau, Sarah A Collier, Michele M Cudahy, Todd A Hopkins

Bioorg Med Chem Lett· July 2008

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Antibacterial oxazolidinones possessing a novel C-5 side chain. (5R)-trans-3-[3-Fluoro-4- (1-oxotetrahydrothiopyran-4-yl)phenyl]-2- oxooxazolidine-5-carboxylic acid amide (PF-00422602), a new lead compound.
Toni-Jo Poel, Richard C Thomas, Wade J Adams, Paul A Aristoff, Michael R Barbachyn, Roger Brideau

J Med Chem· November 2007

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7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase.
Scott D Larsen, Zhijun Zhang, Brian A DiPaolo, Peter R Manninen, Douglas C Rohrer, Roger J Brideau

Bioorg Med Chem Lett· July 2007

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2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases.
Mark E Schnute, David J Anderson, Roger J Brideau, Fred L Ciske, Sarah A Collier

Bioorg Med Chem Lett· June 2007

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4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as non-nucleoside inhibitors of human cytomegalovirus and related herpesvirus polymerases.
Mark E Schnute, Michele M Cudahy, Roger J Brideau, Fred L Homa, Todd A Hopkins

J Med Chem· September 2005

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Inhibition of herpesvirus replication by a series of 4-oxo-dihydroquinolines with viral polymerase activity.
Caroll B Hartline, Emma A Harden, Stephanie L Williams-Aziz, Nicole L Kushner, Roger J Brideau

Antiviral Res· February 2005

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Amino acid changes within conserved region III of the herpes simplex virus and human cytomegalovirus DNA polymerases confer resistance to 4-oxo-dihydroquinolines, a novel class of herpesvirus antiviral agents.
Darrell R Thomsen, Nancee L Oien, Todd A Hopkins, Mary L Knechtel, Roger J Brideau

J Virol· February 2003

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Inhibition of clinical isolates of human cytomegalovirus and varicella zoster virus by PNU-183792, a 4-oxo-dihydroquinoline.
Mary L Knechtel, Audris Huang, Valerie A Vaillancourt, Roger J Brideau

J Med Virol· October 2002

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Broad-spectrum antiviral activity of PNU-183792, a 4-oxo-dihydroquinoline, against human and animal herpesviruses.
Roger J Brideau, Mary L Knechtel, Audris Huang, Valerie A Vaillancourt, Ellen E Vera

Antiviral Res· April 2002

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Broad-spectrum antiherpes activities of 4-hydroxyquinoline carboxamides, a novel class of herpesvirus polymerase inhibitors.
Nancee L Oien, Roger J Brideau, Todd A Hopkins, Janet L Wieber, Mary L Knechtel

Antimicrob Agents Chemother· March 2002

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