Publications by authors named "Roger Rush"

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The c-Abl inhibitor IkT-148009 suppresses neurodegeneration in mouse models of heritable and sporadic Parkinson's disease.
Senthilkumar S Karuppagounder, Hu Wang, Terence Kelly, Roger Rush, Richard Nguyen

Sci Transl Med· January 2023

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Pharmacokinetics of IDX184, a liver-targeted oral prodrug of 2'-methylguanosine-5'-monophosphate, in the monkey and formulation optimization for human exposure.
Xin-Ru Pan-Zhou, Benjamin A Mayes, Hassan Rashidzadeh, Rahela Gasparac, Steven Smith, Roger Rush

Eur J Drug Metab Pharmacokinet· October 2016

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Discovery of novel 2-((pyridin-3-yloxy)methyl)piperazines as α7 nicotinic acetylcholine receptor modulators for the treatment of inflammatory disorders.
Roger B Clark, Diana Lamppu, Lyn Libertine, Amy McDonough, Anjali Kumar, Roger Rush

J Med Chem· May 2014

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Metabolic and Pharmacokinetic Differentiation of STX209 and Racemic Baclofen in Humans.
Raymundo Sanchez-Ponce, Li-Quan Wang, Wei Lu, Jana von Hehn, Maryann Cherubini, Roger Rush

Metabolites· September 2012

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The role of aldehyde oxidase and xanthine oxidase in the biotransformation of a novel negative allosteric modulator of metabotropic glutamate receptor subtype 5.
Ryan D Morrison, Anna L Blobaum, Frank W Byers, Tammy S Santomango, Thomas M Bridges, Roger Rush

Drug Metab Dispos· September 2012

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Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen.
Christina Henderson, Lasani Wijetunge, Mika Nakamoto Kinoshita, Matthew Shumway, Rebecca S Hammond, Roger Rush

Sci Transl Med· September 2012

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Fragile X syndrome: an update on developing treatment modalities.
Aileen Healy, Roger Rush, Timothy Ocain

ACS Chem Neurosci· August 2011

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