Publications by authors named "Ross Thyer"

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Engineering a Bright Near-Infrared Fluorescent Protein by Screening a Comprehensive Phenotypic Landscape.
Devon L Kulhanek, Qiyao Wei, Jared Head, Jessica Hellinger, Zach Jansen, Ross Thyer

bioRxiv· November 2025

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Directed evolution of L-DOPA sensing and production enables efficient incorporation of an expanded genetic code into proteins.
Andrew R Gilmour, Qiyao Wei, Chad Wang, Jessica Hellinger, Vidya Pandarinath, Ross Thyer

bioRxiv· June 2025

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A modular toolkit for environmental , , and enables complex metabolic manipulation.
Zachary Jansen, Abdulaziz Alameri, Qiyao Wei, Devon L Kulhanek, Andrew R Gilmour, Ross Thyer

Appl Environ Microbiol· August 2024

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Interrogating the Function of Bicistronic Translational Control Elements to Improve Consistency of Gene Expression.
Zachary Jansen, Sophia R Reilly, Matan Lieber-Kotz, Andrew Z Li, Qiyao Wei, Ross Thyer

ACS Synth Biol· June 2023

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Using fungible biosensors to evolve improved alkaloid biosyntheses.
Simon d'Oelsnitz, Wantae Kim, Nathaniel T Burkholder, Kamyab Javanmardi, Ross Thyer

Nat Chem Biol· September 2022

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Integrated Top-Down and Bottom-Up Mass Spectrometry for Characterization of Diselenide Bridging Patterns of Synthetic Selenoproteins.
Eleanor Watts, Ross Thyer, Andrew D Ellington, Jennifer S Brodbelt

Anal Chem· August 2022

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DLPacker: Deep learning for prediction of amino acid side chain conformations in proteins.
Mikita Misiura, Raghav Shroff, Ross Thyer, Anatoly B Kolomeisky

Proteins· June 2022

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Directed Evolution of an Improved Aminoacyl-tRNA Synthetase for Incorporation of L-3,4-Dihydroxyphenylalanine (L-DOPA).
Ross Thyer, Simon d'Oelsnitz, Molly S Blevins, Dustin R Klein, Jennifer S Brodbelt

Angew Chem Int Ed Engl· June 2021

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Discovery of Novel Gain-of-Function Mutations Guided by Structure-Based Deep Learning.
Raghav Shroff, Austin W Cole, Daniel J Diaz, Barrett R Morrow, Isaac Donnell, Ross Thyer

ACS Synth Biol· November 2020

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The Role of tRNA in Establishing New Genetic Codes.
Ross Thyer, Andrew D Ellington

Biochemistry· March 2019

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Custom selenoprotein production enabled by laboratory evolution of recoded bacterial strains.
Ross Thyer, Raghav Shroff, Dustin R Klein, Simon d'Oelsnitz, Victoria C Cotham

Nat Biotechnol· August 2018

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Characterization of trimethoprim resistant dihydrofolate reductase mutants by mass spectrometry and inhibition by propargyl-linked antifolates.
Michael Cammarata, Ross Thyer, Michael Lombardo, Amy Anderson, Dennis Wright

Chem Sci· May 2017

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Addicting diverse bacteria to a noncanonical amino acid.
Drew S Tack, Jared W Ellefson, Ross Thyer, Bo Wang, Jimmy Gollihar

Nat Chem Biol· March 2016

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Correction to "Structural Characterization of Dihydrofolate Reductase Complexes by Top-Down Ultraviolet Photodissociation Mass Spectrometry".
Michael B Cammarata, Ross Thyer, Jake Rosenberg, Andrew Ellington, Jennifer S Brodbelt

J Am Chem Soc· March 2016

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Structural Characterization of Dihydrofolate Reductase Complexes by Top-Down Ultraviolet Photodissociation Mass Spectrometry.
Michael B Cammarata, Ross Thyer, Jake Rosenberg, Andrew Ellington, Jennifer S Brodbelt

J Am Chem Soc· July 2015

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Evolving tRNA(Sec) for efficient canonical incorporation of selenocysteine.
Ross Thyer, Scott A Robotham, Jennifer S Brodbelt, Andrew D Ellington

J Am Chem Soc· January 2015

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Synthetic biology: New letters for life's alphabet.
Ross Thyer, Jared Ellefson

Nature· May 2014

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Engineered rRNA enhances the efficiency of selenocysteine incorporation during translation.
Ross Thyer, Aleksandra Filipovska, Oliver Rackham

J Am Chem Soc· January 2013

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Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors.
Oliver Rackham, Anne-Marie J Shearwood, Ross Thyer, Elyshia McNamara, Stefan M K Davies

Free Radic Biol Med· March 2011

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