Publications by authors named "Russell Ware"

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Prolonged, Unintentional Overdose of Hydroxyurea in a Child With Sickle Cell Anemia.
Marina K Girgis, Tyler R Lopachin, T Christy Hallett, Michael A Briones, Neha J Desai, Russell E Ware

Pediatr Blood Cancer· December 2025

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Microsensor Array for the Electrochemical Analysis of Hydroxyurea in Blood Samples of Children Affected by Sickle Cell Anemia.
Rajendra P Shukla, Matan Aroosh, Remi Cazelles, Russell E Ware, Alexander A Vinks

Anal Chem· November 2025

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A New First-Line Option for Pediatric ITP-Incremental Progress or Paradigm Shift?
Omar Niss, Russell E Ware, Charles T Quinn

JAMA· November 2025

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Thirty Years of Hydroxyurea for Sickle Cell Anemia - Scientific Progress, Global Health Gaps.
Enrico Costa, Russell Ware, Leon Tshilolo, Lucio Luzzatto

N Engl J Med· October 2025

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Hydroxyurea pharmacokinetics in children with sickle cell anemia across different global populations.
Alexandra Power-Hays, Kathryn E McElhinney, Thomas N Williams, George Mochamah, Peter Olupot-Olupot, Russell E Ware

Blood Adv· September 2025

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Circulating Immune Complexes and Glucose-6-Phosphate Dehydrogenase Deficiency Predict Recurrent Blackwater Fever in Ugandan Children With Severe Malaria.
Ruth Namazzi, Kagan A Mellencamp, Robert O Opoka, Dibyadyuti Datta, Giselle Lima-Cooper, Russell E Ware

J Infect Dis· August 2025

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Malaria prophylaxis in sickle cell anaemia: some answers, more questions.
Thomas N Williams, Russell E Ware

Lancet Infect Dis· June 2025

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The feasibility of pharmacokinetic-based dosing of hydroxyurea for children with sickle cell anaemia in Uganda: Baseline results of the alternative dosing and prevention of transfusions trial.
Alexandra Power-Hays, Ruth Namazzi, Min Dong, Caroline Kazinga, Charles Kato, Russell E Ware

Br J Clin Pharmacol· June 2025

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Hydroxyurea to decrease stroke risk in children with sickle cell anemia: a systematic review and meta-analysis.
Emmanuela E Ambrose, Paul Alikado Sabuni, Don P Jason Iii, Russell E Ware, Abel N Makubi

Blood Glob Hematol· June 2025

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The modern use of hydroxyurea for children with sickle cell anemia.
Charles T Quinn, Russell E Ware

Haematologica· May 2025

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Primary Stroke Screening and Hydroxyurea Treatment for Sickle Cell Anemia in Pediatric Healthcare Settings in East and Central Africa: A Narrative Review of Capacity Gaps and Opportunities.
Teresa Smith Latham, Katarzyna Czabanowska, Suzanne Babich, Faith Yego-Kosgei, Lisa M Shook, Russell E Ware

Public Health Rev· May 2025

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Stroke prevention in Hispanic children with sickle cell anemia: the SACRED trial.
Rosa M Nieves, Teresa Latham, Nicolle Marte, Melissa Berges, Luisanna M Sánchez, Russell E Ware

Blood Adv· April 2025

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The feasibility of pharmacokinetic-based dosing of hydroxyurea for children with sickle cell anaemia in Uganda: Baseline results of the alternative dosing and prevention of transfusions trial.
Alexandra Power-Hays, Ruth Namazzi, Min Dong, Caroline Kazinga, Charles Kato, Russell E Ware

Br J Clin Pharmacol· April 2025

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Pharmacokinetic-Guided Hydroxyurea to Reduce Transfusions in Ugandan Children with Sickle Cell Anemia: Study Design of the Alternative Dosing And Prevention of Transfusions Trial.
Alexandra Power-Hays, Ruth Namazzi, Charles Kato, Kathryn E McElhinney, Andrea L Conroy, Russell E Ware

Acta Haematol· March 2025

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The Voxelotor Effect: Decreased Affinity for New Drugs for Sickle Cell Disease?
Charles T Quinn, Russell E Ware

Pediatr Blood Cancer· March 2025

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Hydroxyurea for Children and Adults with Hemoglobin SC Disease.
Yvonne A Dei-Adomakoh, Catherine I Segbefia, Teresa S Latham, Adam C Lane, Klenam Dzefi-Tettey, Russell E Ware

NEJM Evid· February 2025

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Globalization in clinical drug development for sickle cell disease.
Enrico Costa, Russell E Ware, Léon Tshilolo, Julie Makani, Hubert G M Leufkens

Am J Hematol· January 2025

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Baseline characteristics of Ghanaian children and adults enrolled in PIVOT, a randomised clinical trial of hydroxyurea in HbSC disease in sub-Saharan Africa.
Catherine I Segbefia, Luke R Smart, Susan E Stuber, Kwesi N Amissah-Arthur, Klenam Dzefi-Tettey, Russell E Ware

Br J Haematol· December 2024

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A pharmacokinetic-pharmacodynamic analysis of l-glutamine for the treatment of sickle cell disease: Implications for understanding the mechanism of action and evaluating response to therapy.
Alina Sadaf, Min Dong, Amanda Pfeiffer, Jennifer Korpik, Theodosia A Kalfa, Russell E Ware

Br J Haematol· September 2024

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Hydroxyurea dose optimisation for children with sickle cell anaemia in sub-Saharan Africa (REACH): extended follow-up of a multicentre, open-label, phase 1/2 trial.
Banu Aygun, Adam Lane, Luke R Smart, Brígida Santos, Léon Tshilolo, Russell E Ware

Lancet Haematol· June 2024

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Successes and pitfalls in orphan drug development for sickle cell disease.
Enrico Costa, Antonella Isgrò, Mariane de Montalembert, Hubert G M Leufkens, Russell E Ware

Blood Adv· May 2024

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Reducing transfusion utilization for children with sickle cell anemia in sub-Saharan Africa with hydroxyurea: Analysis from the phase I/II REACH trial.
Alexandra Power-Hays, George A Tomlinson, Leon Tshilolo, Brígida Santos, Thomas N Williams, Russell E Ware

Am J Hematol· April 2024

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Angiopoietin-2 is associated with sickle cell complications, including stroke risk, and decreases with hydroxyurea therapy.
Thomas F Siegert, Robert O Opoka, Maria Nakafeero, Aubri Carman, Kagan A Mellencamp, Russell E Ware

Blood Vessel Thromb Hemost· March 2024

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A Population Pharmacokinetic Analysis of L-Glutamine Exposure in Patients with Sickle Cell Disease: Evaluation of Dose and Food Effects.
Alina Sadaf, Min Dong, Amanda Pfeiffer, Teresa Latham, Theodosia Kalfa, Russell E Ware

Clin Pharmacokinet· March 2024

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The bold promise of gene therapy for sickle cell disease.
Russell E Ware, Charles T Quinn

Br J Haematol· February 2024

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