Publications by authors named "Ryan Whaley"

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Advancing Clinical Pharmacogenomics Worldwide Through the Clinical Pharmacogenetics Implementation Consortium (CPIC).
Kelly E Caudle, Michelle Whirl-Carrillo, Mary V Relling, James M Hoffman, Roseann S Donnelly, Ryan Whaley

Clin Pharmacol Ther· December 2025

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Frequencies of pharmacogenomic alleles across biogeographic groups in a large-scale biobank.
Binglan Li, Katrin Sangkuhl, Ryan Whaley, Mark Woon, Karl Keat

Am J Hum Genet· October 2023

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How to Run the Pharmacogenomics Clinical Annotation Tool (PharmCAT).
Binglan Li, Katrin Sangkuhl, Karl Keat, Ryan M Whaley, Mark Woon

Clin Pharmacol Ther· May 2023

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An Evidence-Based Framework for Evaluating Pharmacogenomics Knowledge for Personalized Medicine.
Michelle Whirl-Carrillo, Rachel Huddart, Li Gong, Katrin Sangkuhl, Caroline F Thorn, Ryan Whaley

Clin Pharmacol Ther· September 2021

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PGxMine: Text mining for curation of PharmGKB.
Jake Lever, Julia M Barbarino, Li Gong, Rachel Huddart, Katrin Sangkuhl, Ryan Whaley

Pac Symp Biocomput· February 2021

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Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium.
Shefali Setia Verma, Thomas O Bergmeijer, Li Gong, Jean-Luc Reny, Joshua P Lewis, Ryan Whaley

Clin Pharmacol Ther· November 2020

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Pharmacogenomic polygenic response score predicts ischaemic events and cardiovascular mortality in clopidogrel-treated patients.
Joshua P Lewis, Joshua D Backman, Jean-Luc Reny, Thomas O Bergmeijer, Braxton D Mitchell, Ryan M Whaley

Eur Heart J Cardiovasc Pharmacother· July 2020

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Pharmacogenomics Clinical Annotation Tool (PharmCAT).
Katrin Sangkuhl, Michelle Whirl-Carrillo, Ryan M Whaley, Mark Woon, Adam Lavertu

Clin Pharmacol Ther· January 2020

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The association of obesity and coronary artery disease genes with response to SSRIs treatment in major depression.
Azmeraw T Amare, Klaus Oliver Schubert, Fasil Tekola-Ayele, Yi-Hsiang Hsu, Katrin Sangkuhl, Ryan M Whaley

J Neural Transm (Vienna)· January 2019

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Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC).
Thomas O Bergmeijer, Jean-Luc Reny, Ruth E Pakyz, Li Gong, Joshua P Lewis, Ryan M Whaley

Am Heart J· April 2018

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Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder.
Azmeraw T Amare, Klaus Oliver Schubert, Fasil Tekola-Ayele, Yi-Hsiang Hsu, Katrin Sangkuhl, Ryan M Whaley

Front Psychiatry· March 2018

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Life beyond kinases: structure-based discovery of sorafenib as nanomolar antagonist of 5-HT receptors.
Xingyu Lin, Xi-Ping Huang, Gang Chen, Ryan Whaley, Shiming Peng

J Med Chem· June 2012

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The BioPAX community standard for pathway data sharing.
Emek Demir, Michael P Cary, Suzanne Paley, Ken Fukuda, Christian Lemer, Ryan Whaley

Nat Biotechnol· September 2010

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Clinical assessment incorporating a personal genome.
Euan A Ashley, Atul J Butte, Matthew T Wheeler, Rong Chen, Teri E Klein, Ryan Whaley

Lancet· May 2010

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Predicting new molecular targets for known drugs.
Michael J Keiser, Vincent Setola, John J Irwin, Christian Laggner, Atheir I Abbas, Ryan Whaley

Nature· November 2009

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CHIP deficiency decreases longevity, with accelerated aging phenotypes accompanied by altered protein quality control.
Jin-Na Min, Ryan A Whaley, Norman E Sharpless, Pamela Lockyer, Andrea L Portbury

Mol Cell Biol· June 2008

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The pharmacogenetics and pharmacogenomics knowledge base: accentuating the knowledge.
Tina Hernandez-Boussard, Michelle Whirl-Carrillo, Joan M Hebert, Li Gong, Ryan Owen, Ryan Whaley

Nucleic Acids Res· January 2008

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CHIP activates HSF1 and confers protection against apoptosis and cellular stress.
Qian Dai, Chunlian Zhang, Yaxu Wu, Holly McDonough, Ryan A Whaley

EMBO J· October 2003

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