Publications by authors named "Sam Hart"

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Cryo-EM structure of the CDK2-cyclin A-CDC25A complex.
Rhianna J Rowland, Svitlana Korolchuk, Marco Salamina, Natalie J Tatum, James R Ault, Sam Hart

Nat Commun· August 2024

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Deciphering complexity in Pd-catalyzed cross-couplings.
George E Clarke, James D Firth, Lyndsay A Ledingham, Chris S Horbaczewskyj, Richard A Bourne, Sam Hart

Nat Commun· May 2024

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Structural analysis of five-coordinate aluminium(salen) complexes and its relationship to their catalytic activity.
Heather Fish, Sam Hart, Katie J Lamb, Michael North, Sophie C Z Quek

Dalton Trans· January 2021

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Solvent- and anion-dependent rearrangement of fluorinated carbene ligands provides access to fluorinated alkenes.
Lewis M Hall, Lucy M Milner, Sam J Hart, Adrian C Whitwood, Jason M Lynam

Dalton Trans· December 2019

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Using coligands to gain mechanistic insight into iridium complexes hyperpolarized with -hydrogen.
Ben J Tickner, Richard O John, Soumya S Roy, Sam J Hart, Adrian C Whitwood

Chem Sci· May 2019

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Filling a Niche in "Ligand Space" with Bulky, Electron-Poor Phosphorus(III) Alkoxides.
Sharifa Hussein, Denis Priester, Paul Beet, Jonathon Cottom, Sam J Hart

Chemistry· February 2019

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Structure and function of a glycoside hydrolase family 8 endoxylanase from Teredinibacter turnerae.
Claire A Fowler, Glyn R Hemsworth, Fiona Cuskin, Sam Hart, Johan Turkenburg

Acta Crystallogr D Struct Biol· October 2018

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Fine-tuning the efficiency of para-hydrogen-induced hyperpolarization by rational N-heterocyclic carbene design.
Peter J Rayner, Philip Norcott, Kate M Appleby, Wissam Iali, Richard O John, Sam J Hart

Nat Commun· October 2018

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Using signal amplification by reversible exchange (SABRE) to hyperpolarise Sn and Si NMR nuclei.
Alexandra M Olaru, Alister Burt, Peter J Rayner, Sam J Hart, Adrian C Whitwood

Chem Commun (Camb)· December 2016

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Iridium Cyclooctene Complex That Forms a Hyperpolarization Transfer Catalyst before Converting to a Binuclear C-H Bond Activation Product Responsible for Hydrogen Isotope Exchange.
Wissam Iali, Gary G R Green, Sam J Hart, Adrian C Whitwood, Simon B Duckett

Inorg Chem· November 2016

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Rapid Markovnikov addition of HCl to a pendant alkyne: evidence for a quinoidal cumulene.
Samantha G Eaves, Sam J Hart, Adrian C Whitwood, Dmitry S Yufit, Paul J Low

Chem Commun (Camb)· June 2015

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Structure, Activity and Stereoselectivity of NADPH-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline.
Henry Man, Elizabeth Wells, Shahed Hussain, Friedemann Leipold, Sam Hart

Chembiochem· May 2015

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Structures of the Apo and FAD-bound forms of 2-hydroxybiphenyl 3-monooxygenase (HbpA) locate activity hotspots identified by using directed evolution.
Chantel N Jensen, Tamara Mielke, Joseph E Farrugia, Annika Frank, Henry Man, Sam Hart

Chembiochem· April 2015

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Halogen- and hydrogen-bonded salts and co-crystals formed from 4-halo-2,3,5,6-tetrafluorophenol and cyclic secondary and tertiary amines: orthogonal and non-orthogonal halogen and hydrogen bonding, and synthetic analogues of halogen-bonded biological systems.
Akihiro Takemura, Linda J McAllister, Sam Hart, Natalie E Pridmore, Peter B Karadakov

Chemistry· May 2014

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Iridium(III) hydrido N-heterocyclic carbene-phosphine complexes as catalysts in magnetization transfer reactions.
Marianna Fekete, Oliver W Bayfield, Simon B Duckett, Sam Hart, Ryan E Mewis

Inorg Chem· December 2013

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Structure and activity of NADPH-dependent reductase Q1EQE0 from Streptomyces kanamyceticus, which catalyses the R-selective reduction of an imine substrate.
María Rodríguez-Mata, Annika Frank, Elizabeth Wells, Friedemann Leipold, Nicholas J Turner, Sam Hart

Chembiochem· July 2013

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Structures of a γ-aminobutyrate (GABA) transaminase from the s-triazine-degrading organism Arthrobacter aurescens TC1 in complex with PLP and with its external aldimine PLP-GABA adduct.
Heather Bruce, Anh Nguyen Tuan, Juan Mangas Sánchez, Charlotte Leese, Jennifer Hopwood, Sam Hart

Acta Crystallogr Sect F Struct Biol Cryst Commun· October 2012

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A flavoprotein monooxygenase that catalyses a Baeyer-Villiger reaction and thioether oxidation using NADH as the nicotinamide cofactor.
Chantel N Jensen, Jared Cartwright, Jonathan Ward, Sam Hart, Johan P Turkenburg

Chembiochem· April 2012

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A covalent succinylcysteine-like intermediate in the enzyme-catalyzed transformation of maleate to fumarate by maleate isomerase.
Florian Fisch, Carlos Martinez Fleites, Marie Delenne, Nina Baudendistel, Bernhard Hauer, Sam Hart

J Am Chem Soc· August 2010

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Palliative care for people severely affected by multiple sclerosis: evaluation of a novel palliative care service.
Polly Edmonds, Sam Hart, Wei Gao, Bella Vivat, Rachel Burman

Mult Scler· May 2010

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Is short-term palliative care cost-effective in multiple sclerosis? A randomized phase II trial.
Irene J Higginson, Paul McCrone, Sam R Hart, Rachel Burman, Eli Silber

J Pain Symptom Manage· December 2009

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The 1.5-A structure of XplA-heme, an unusual cytochrome P450 heme domain that catalyzes reductive biotransformation of royal demolition explosive.
Federico Sabbadin, Rosamond Jackson, Kamran Haider, Girish Tampi, Johan P Turkenburg, Sam Hart

J Biol Chem· October 2009

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The structure of monoamine oxidase from Aspergillus niger provides a molecular context for improvements in activity obtained by directed evolution.
Kate E Atkin, Renate Reiss, Valentin Koehler, Kevin R Bailey, Sam Hart

J Mol Biol· December 2008

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Randomised controlled trial of a new palliative care service: Compliance, recruitment and completeness of follow-up.
Irene J Higginson, Sam Hart, Rachel Burman, Eli Silber, Tariq Saleem

BMC Palliat Care· May 2008

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Needs assessments in palliative care: an appraisal of definitions and approaches used.
Irene J Higginson, Sam Hart, Jonathan Koffman, Lucy Selman, Richard Harding

J Pain Symptom Manage· May 2007

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