Publications by authors named "Sam Rebello"

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Pharmacokinetics of AXA1665, a Novel Composition of Amino Acids, in Comparison With Protein Supplement: A Single-Dose, Open-Label, Randomized Study in Healthy Subjects.
Soniya Vaidya, Joshua McLinden, Paul Hinderliter, Noriaki Tatsuta, Alexandra Steinberg, Sam Rebello

Clin Pharmacol Drug Dev· July 2023

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Safety, Tolerability, and Physiological Effects of AXA1665, a Novel Composition of Amino Acids, in Subjects With Child-Pugh A and B Cirrhosis.
Manu V Chakravarthy, Joel Neutel, Scharmen Confer, Peng Zhao, Noriaki Tatsuta, Sam Rebello

Clin Transl Gastroenterol· August 2020

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Simultaneous Physiologically Based Pharmacokinetic (PBPK) Modeling of Parent and Active Metabolites to Investigate Complex CYP3A4 Drug-Drug Interaction Potential: A Case Example of Midostaurin.
Helen Gu, Catherine Dutreix, Sam Rebello, Taoufik Ouatas, Lai Wang

Drug Metab Dispos· February 2018

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A Physiologically-Based Pharmacokinetic Modeling Approach To Predict Drug-Drug Interactions of Sonidegib (LDE225) with Perpetrators of CYP3A in Cancer Patients.
Heidi J Einolf, Jocelyn Zhou, Christina Won, Lai Wang, Sam Rebello

Drug Metab Dispos· April 2017

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An Exposure-Response Modeling Approach to Examine the Relationship Between Potency of CYP3A Inducer and Plasma 4β-Hydroxycholesterol in Healthy Subjects.
Xuemin Jiang, Catherine Dutreix, Venkateswar Jarugula, Sam Rebello, Christina S Won

Clin Pharmacol Drug Dev· January 2017

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Compelling Relationship of CYP3A Induction to Levels of the Putative Biomarker 4β-Hydroxycholesterol and Changes in Midazolam Exposure.
James B Mangold, Fan Wu, Sam Rebello

Clin Pharmacol Drug Dev· July 2016

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Assessment of pharmacokinetic drug-drug interaction between pradigastat and atazanavir or probenecid.
Anisha Mendonza, Imad Hanna, Dan Meyers, Phillip Koo, Srikanth Neelakantham, Sam Rebello

J Clin Pharmacol· March 2016

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Effects of age and sex on the pharmacokinetics of LCZ696, an angiotensin receptor neprilysin inhibitor.
Lu Gan, Thomas Langenickel, Jesika Petruck, Kiran Kode, Iris Rajman, Sam Rebello

J Clin Pharmacol· January 2016

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Pharmacokinetic drug-drug interaction assessment of LCZ696 (an angiotensin receptor neprilysin inhibitor) with omeprazole, metformin or levonorgestrel-ethinyl estradiol in healthy subjects.
Lu Gan, Xuemin Jiang, Anisha Mendonza, Therese Swan, Christine Reynolds, Sam Rebello

Clin Pharmacol Drug Dev· January 2016

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Pharmacokinetic drug-drug interaction assessment between LCZ696, an angiotensin receptor neprilysin inhibitor, and hydrochlorothiazide, amlodipine, or carvedilol.
Hsiu-Ling Hsiao, Thomas Heiko Langenickel, Michael Greeley, John Roberts, Wei Zhou, Sam Rebello

Clin Pharmacol Drug Dev· November 2015

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Evaluation of food effect on the oral bioavailability of pradigastat, a diacylglycerol acyltransferase 1 inhibitor.
Surya P Ayalasomayajula, Charles D Meyers, Jing Yu, Mark Kagan, Ralph Matott, Sam Rebello

Biopharm Drug Dispos· October 2015

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Effect of Renal Impairment on the Pharmacokinetics of Pradigastat, a Novel Diacylglycerol Acyltransferase1 (DGAT1) Inhibitor.
Sachiko Mita, Dan Meyers, Parasar Pal, TsuHan Lin, Tapan Majumdar, Sam Rebello

Clin Pharmacokinet· July 2015

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Effect of Hepatic Impairment on the Pharmacokinetics of Pradigastat, a Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitor.
Masaru Hirano, Dan Meyers, GangaRaju Golla, Parasar Pal, Pascale Pinot, Sam Rebello

Clin Pharmacokinet· July 2015

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Evaluation of a potential transporter-mediated drug interaction between rosuvastatin and pradigastat, a novel DGAT-1 inhibitor.
Kenneth Kulmatycki, Imad Hanna, Dan Meyers, Atish Salunke, Aishwarya Movva, Sam Rebello

Int J Clin Pharmacol Ther· May 2015

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Assessment of pharmacokinetic drug-drug interaction between pradigastat and acetaminophen in healthy subjects.
Surya Ayalasomayajula, Dan Meyers, Phillip Koo, Atish Salunke, Tapan Majumdar, Sam Rebello

Eur J Clin Pharmacol· April 2015

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Effect of pradigastat, a diacylglycerol acyltransferase 1 inhibitor, on the pharmacokinetics of a combination oral contraceptive in healthy female subjects.
Jin Chen, Suraj Bhansali, Srikanth Neelakantham, Craig Trusley, Tapan Majumdar, Sam Rebello

Int J Clin Pharmacol Ther· April 2015

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Aldosterone synthase inhibition: cardiorenal protection in animal disease models and translation of hormonal effects to human subjects.
Joël Ménard, Dean F Rigel, Catherine Watson, Arco Y Jeng, Fumin Fu, Sam Rebello

J Transl Med· December 2014

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Pharmacokinetic and pharmacodynamic drug-drug interaction assessment between pradigastat and digoxin or warfarin.
Jing-He Yan, Dan Meyers, Zachary Lee, Kate Danis, Srikanth Neelakantham, Sam Rebello

J Clin Pharmacol· July 2014

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A semi-automated LC-MS/MS method for the determination of LCI699, a steroid 11β-hydroxylase inhibitor, in human plasma.
Wenkui Li, Suyi Luo, Sam Rebello, Jimmy Flarakos, Francis L S Tse

J Chromatogr B Analyt Technol Biomed Life Sci· June 2014

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Pharmacokinetics of aliskiren in patients with end-stage renal disease undergoing haemodialysis.
Dmytro Khadzhynov, Torsten Slowinski, Ina Lieker, Hans-Hellmut Neumayer, Diego Albrecht, Sam Rebello

Clin Pharmacokinet· October 2012

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Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects.
Sam Rebello, Sally Zhao, Sam Hariry, Marion Dahlke, Natalya Alexander

Eur J Clin Pharmacol· May 2012

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Structure-based library design and the discovery of a potent and selective mast cell β-tryptase inhibitor as an oral therapeutic agent.
Guyan Liang, Suzanne Aldous, Gregory Merriman, Julian Levell, James Pribish, Sam Rebello

Bioorg Med Chem Lett· January 2012

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Effect of cyclosporine on the pharmacokinetics of aliskiren in healthy subjects.
Sam Rebello, Séverine Compain, Aimin Feng, Sam Hariry, Hans-Armin Dieterich

J Clin Pharmacol· November 2011

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Effect of verapamil on the pharmacokinetics of aliskiren in healthy participants.
Sam Rebello, Selene Leon, Sam Hariry, Marion Dahlke, Venkateswar Jarugula

J Clin Pharmacol· February 2011

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Disposition of morphine in plasma and cerebrospinal fluid varies during neonatal development in pigs.
Aarati Rai, Shaifali Bhalla, Sam S Rebello, Helen Kastrissios, Anil Gulati

J Pharm Pharmacol· August 2005

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