Publications by authors named "Sampathkumar Parthasarathy"

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WNT Mimetic-Induced Lacrimal Gland Regeneration Reverses Aqueous Tear Deficiency.
Huy Nguyen, Russell B Fletcher, Tom Lopez, Elizabeth Whisler, Kelsey R Logas, Parthasarathy Sampathkumar

Transl Vis Sci Technol· June 2025

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Targeted protein degradation systems to enhance Wnt signaling.
Parthasarathy Sampathkumar, Heekyung Jung, Hui Chen, Zhengjian Zhang, Nicholas Suen

Elife· June 2024

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Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain.
Anniina T Virtanen, Teemu Haikarainen, Parthasarathy Sampathkumar, Maaria Palmroth, Sanna Liukkonen

Pharmaceuticals (Basel)· January 2023

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SZN-413, a FZD4 Agonist, as a Potential Novel Therapeutic for the Treatment of Diabetic Retinopathy.
Huy Nguyen, Hui Chen, Meghah Vuppalapaty, Elizabeth Whisler, Kelsey Ronarda Logas, Parthasarathy Sampathkumar

Transl Vis Sci Technol· September 2022

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Stilbene epoxidation and detoxification in a -nematode symbiosis.
Hyun Bong Park, Parthasarathy Sampathkumar, Corey E Perez, Joon Ha Lee, Jeannie Tran

J Biol Chem· April 2017

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Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex.
Paula Upla, Seung Joong Kim, Parthasarathy Sampathkumar, Kaushik Dutta, Sean M Cahill

Structure· March 2017

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Integrative structure-function mapping of the nucleoporin Nup133 suggests a conserved mechanism for membrane anchoring of the nuclear pore complex.
Seung Joong Kim, Javier Fernandez-Martinez, Parthasarathy Sampathkumar, Anne Martel, Tsutomu Matsui

Mol Cell Proteomics· November 2014

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Crystal structure of human Karyopherin β2 bound to the PY-NLS of Saccharomyces cerevisiae Nab2.
Michael Soniat, Parthasarathy Sampathkumar, Garen Collett, Anthony S Gizzi, Radhika N Banu

J Struct Funct Genomics· June 2013

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Structure, dynamics, evolution, and function of a major scaffold component in the nuclear pore complex.
Parthasarathy Sampathkumar, Seung Joong Kim, Paula Upla, William J Rice, Jeremy Phillips

Structure· April 2013

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Atomic structure of the nuclear pore complex targeting domain of a Nup116 homologue from the yeast, Candida glabrata.
Parthasarathy Sampathkumar, Seung Joong Kim, Danalyn Manglicmot, Kevin T Bain, Jeremiah Gilmore

Proteins· August 2012

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Structure of the C-terminal domain of Saccharomyces cerevisiae Nup133, a component of the nuclear pore complex.
Parthasarathy Sampathkumar, Tarun Gheyi, Stacy A Miller, Kevin T Bain, Mark Dickey

Proteins· May 2011

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ModBase, a database of annotated comparative protein structure models, and associated resources.
Ursula Pieper, Benjamin M Webb, David T Barkan, Dina Schneidman-Duhovny, Avner Schlessinger, Parthasarathy Sampathkumar

Nucleic Acids Res· January 2011

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Structure of a putative BenF-like porin from Pseudomonas fluorescens Pf-5 at 2.6 A resolution.
Parthasarathy Sampathkumar, Frances Lu, Xun Zhao, Zhenzhen Li, Jeremiah Gilmore

Proteins· November 2010

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Structures of the autoproteolytic domain from the Saccharomyces cerevisiae nuclear pore complex component, Nup145.
Parthasarathy Sampathkumar, Sinem A Ozyurt, Johnny Do, Kevin T Bain, Mark Dickey

Proteins· June 2010

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Structures of PHR domains from Mus musculus Phr1 (Mycbp2) explain the loss-of-function mutation (Gly1092-->Glu) of the C. elegans ortholog RPM-1.
Parthasarathy Sampathkumar, Sinem A Ozyurt, Stacy A Miller, Kevin T Bain, Marc E Rutter

J Mol Biol· April 2010

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Structural insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5.
Parthasarathy Sampathkumar, Claudia Roach, Paul A M Michels, Wim G J Hol

J Mol Biol· September 2008

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NADP+ expels both the co-factor and a substrate analog from the Mycobacterium tuberculosis ThyX active site: opportunities for anti-bacterial drug design.
Parthasarathy Sampathkumar, Stewart Turley, Carol Hopkins Sibley, Wim G J Hol

J Mol Biol· June 2006

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Structure of the Mycobacterium tuberculosis flavin dependent thymidylate synthase (MtbThyX) at 2.0A resolution.
Parthasarathy Sampathkumar, Stewart Turley, Jonathan E Ulmer, Ho Gun Rhie, Carol Hopkins Sibley

J Mol Biol· October 2005

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Synthesis and characterization of bioconjugates of S-layer proteins.
Parthasarathy Sampathkumar, M Lane Gilchrist

Bioconjug Chem· January 2005

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Structure of Plasmodium falciparum triose-phosphate isomerase-2-phosphoglycerate complex at 1.1-A resolution.
Sampathkumar Parthasarathy, Kandiah Eaazhisai, Hemalatha Balaram, Padmanabhan Balaram, Mathur R N Murthy

J Biol Chem· December 2003

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