Publications by authors named "Samuel Constant"

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Influenza A(H1N1)pdm09 virus resistance to baloxavir, oseltamivir and sialic acid mimetics in single and dual therapies: Insights from human airway epithelia and murine models.
Clément Fage, Sheryline Loison, Arnaud Charles-Antoine Zwygart, Romain Poli, Stéphane Rosset, Samuel Constant

Antiviral Res· July 2025

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Silicon Carbide Nanowires Impair Mucociliary Clearance-Mediated Innate Immunity in Primary Human Bronchial Epithelial Cells.
Ziting Wang, Jimmy Vernaz, Nikolaos Tagaras, Bernadett Boda, Tina Buerki-Thurnherr, Samuel Constant

ACS Nano· June 2025

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A Novel In Vitro Primary Human Alveolar Model (AlveolAir™) for H1N1 and SARS-CoV-2 Infection and Antiviral Screening.
Cindia Ferreira Lopes, Emilie Laurent, Mireille Caul-Futy, Julia Dubois, Chloé Mialon, Samuel Constant

Microorganisms· March 2025

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Evaluation of a non-animal toolbox informed by adverse outcome pathways for human inhalation safety.
Renato Ivan de Ávila, Iris Müller, Hugh Barlow, Alistair Mark Middleton, Mathura Theiventhran, Samuel Constant

Front Toxicol· February 2025

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Minimum information for reporting on the TEER (trans-epithelial/endothelial electrical resistance) assay (MIRTA).
Monita Sharma, Erin Huber, Emma Arnesdotter, Holger P Behrsing, Adam Bettmann, Samuel Constant

Arch Toxicol· January 2025

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Development of Broad-Spectrum β-Cyclodextrins-Based Nanomaterials Against Influenza Viruses.
Arnaud Charles-Antoine Zwygart, Chiara Medaglia, Yong Zhu, E Bart Tarbet, Westover Jonna, Samuel Constant

J Med Virol· December 2024

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Rheological comparison of sputum and reconstituted airway epithelium mucus.
Lydia Esteban Enjuto, Vassylia Taty Poaty, Mendy Bouveret, Huang Song, Samuel Constant

Sci Rep· December 2024

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The triple combination of Remdesivir (GS-441524), Molnupiravir and Ribavirin is highly efficient in inhibiting coronavirus replication in human nasal airway epithelial cell cultures and in a hamster infection model.
Thuc Nguyen Dan Do, Rana Abdelnabi, Bernadett Boda, Samuel Constant, Johan Neyts

Antiviral Res· November 2024

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Effect of cyclosporin A on respiratory viral replication in fully differentiated ex vivo human airway epithelia.
Louise Bondeelle, Song Huang, Samuel Constant, Sophie Clément, Maud Salmona

Pharmacol Res Perspect· October 2024

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Astodrimer sodium nasal spray forms a barrier to SARS-CoV-2 in vitro and preserves normal mucociliary function in human nasal epithelium.
Jeremy R A Paull, Carolyn A Luscombe, Aynaz Seta, Graham P Heery, Michael D Bobardt, Samuel Constant

Sci Rep· September 2024

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Multidrug Combinations against SARS-CoV-2 Using GS-441524 or Ivermectin with Molnupiravir and/or Nirmatrelvir in Reconstituted Human Nasal Airway Epithelia.
Denise Siegrist, Hulda R Jonsdottir, Mendy Bouveret, Bernadett Boda, Samuel Constant

Pharmaceutics· September 2024

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Establishment of a human nasal epithelium model of histamine-induced inflammation to assess the activity of fexofenadine as an inverse agonist and its link to clinical benefit.
Anne Barbot, Michele Lheritier-Barrand, Margarita Murrieta-Aguttes, Maud Leonetti, Jimmy Vernaz, Samuel Constant

Front Pharmacol· June 2024

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The triple combination of Remdesivir (GS-441524), Molnupiravir and Ribavirin is highly efficient in inhibiting coronavirus replication in human nasal airway epithelial cell cultures and in a hamster infection model.
Thuc Nguyen Dan Do, Rana Abdelnabi, Bernadett Boda, Samuel Constant, Johan Neyts

bioRxiv· May 2024

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Inefficient antiviral response in reconstituted small-airway epithelium from chronic obstructive pulmonary disease patients following human parainfluenza virus type 3 infection.
Louise Bondeelle, Maud Salmona, Véronique Houdouin, Elise Diaz, Jacques Dutrieux, Samuel Constant

Virol J· April 2024

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Antiviral properties of trans-δ-viniferin derivatives against enveloped viruses.
Arnaud Charles-Antoine Zwygart, Chiara Medaglia, Robin Huber, Romain Poli, Laurence Marcourt, Samuel Constant

Biomed Pharmacother· July 2023

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Inactivation of SARS-CoV-2 on salt-coated surfaces: an in vitro study.
Monika Gsell, Xavier Bulliard, Sandra Schorderet Weber, Yang Xiang, Samuel Constant

Arch Microbiol· June 2023

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Altered cell function and increased replication of rhinoviruses and EV-D68 in airway epithelia of asthma patients.
Manel Essaidi-Laziosi, Léna Royston, Bernadett Boda, Francisco Javier Pérez-Rodriguez, Isabelle Piuz, Samuel Constant

Front Microbiol· March 2023

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An anti-influenza combined therapy assessed by single cell RNA-sequencing.
Chiara Medaglia, Ilya Kolpakov, Arnaud Charles-Antoine Zwygart, Yong Zhu, Samuel Constant

Commun Biol· October 2022

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In vitro testing of salt coating of fabrics as a potential antiviral agent in reusable face masks.
Sandra Schorderet Weber, Xavier Bulliard, Rosy Bonfante, Yang Xiang, Silvia Biselli, Samuel Constant

Sci Rep· October 2022

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Comparison of tissue tropism and host response to enteric and respiratory enteroviruses.
Ines Cordeiro Filipe, Han Kang Tee, Julien Prados, Isabelle Piuz, Samuel Constant

PLoS Pathog· July 2022

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Molnupiravir combined with different repurposed drugs further inhibits SARS-CoV-2 infection in human nasal epithelium in vitro.
Hulda R Jonsdottir, Denise Siegrist, Thomas Julien, Blandine Padey, Mendy Bouveret, Samuel Constant

Biomed Pharmacother· June 2022

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Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2.
David C Schultz, Robert M Johnson, Kasirajan Ayyanathan, Jesse Miller, Kanupriya Whig, Samuel Constant

Nature· April 2022

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Drug-Free Nasal Spray as a Barrier against SARS-CoV-2 and Its Delta Variant: In Vitro Study of Safety and Efficacy in Human Nasal Airway Epithelia.
Fabio Fais, Reda Juskeviciene, Veronica Francardo, Stéphanie Mateos, Manuela Guyard, Samuel Constant

Int J Mol Sci· April 2022

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Iota-carrageenan extracted from red algae is a potent inhibitor of SARS-CoV-2 infection in reconstituted human airway epithelia.
David Bovard, Marco van der Toorn, Walter K Schlage, Samuel Constant, Kasper Renggli

Biochem Biophys Rep· March 2022

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Towards More Predictive, Physiological and Animal-free Models: Advances in Cell and Tissue Culture 2020 Conference Proceedings.
Bhumika Singh, Mohamed Essameldin Abdelgawad, Zulfiqur Ali, Jarrod Bailey, Elisa Budyn, Samuel Constant

Altern Lab Anim· May 2021

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