Publications by authors named "Samuel Pfaff"

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A genetically-defined population of amygdalofugal neurons promotes suckling and early postnatal growth.
Jeffrey D Moore, Lukas C Bachmann, Lauren E McElvain, Samuel L Pfaff, Catherine Dulac

bioRxiv· October 2025

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Non-genetic neuromodulation with graphene optoelectronic actuators for disease models, stem cell maturation, and biohybrid robotics.
Elena Molokanova, Teng Zhou, Pragna Vasupal, Volodymyr P Cherkas, Prashant Narute, Samuel L Pfaff

Nat Commun· August 2025

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Scp776, A Novel IGF-1 Fusion Protein for Acute Therapy to Promote Escape From Apoptosis in Tissues Affected by Ischemic Injury: 2 Randomized Placebo-Controlled Phase 1 Studies in Healthy Adults.
Samuel J Pfaff, Terry O'Reilly, Yan Zhang, Walter Olsen, Kristopher Kuchenbecker

Clin Pharmacol Drug Dev· January 2025

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Ultraflexible electrodes for recording neural activity in the mouse spinal cord during motor behavior.
Yu Wu, Benjamin A Temple, Nicole Sevilla, Jiaao Zhang, Hanlin Zhu, Samuel L Pfaff

Cell Rep· May 2024

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Mitf is a Schwann cell sensor of axonal integrity that drives nerve repair.
Lydia Daboussi, Giancarlo Costaguta, Miriam Gullo, Nicole Jasinski, Veronica Pessino, Samuel L Pfaff

Cell Rep· November 2023

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The β-adrenergic receptor links sympathetic nerves to T cell exhaustion.
Anna-Maria Globig, Steven Zhao, Jessica Roginsky, Vivien I Maltez, Juan Guiza, Samuel Pfaff

Nature· October 2023

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Expandable Sendai-Virus-Reprogrammed Human iPSC-Neuronal Precursors: Post-Grafting Safety Characterization in Rats and Adult Pig.
Yoshiomi Kobayashi, Michiko Shigyo, Oleksandr Platoshyn, Silvia Marsala, Tomohisa Kato, Samuel L Pfaff

Cell Transplant· May 2023

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A spinal synergy of excitatory and inhibitory neurons coordinates ipsilateral body movements.
Marito Hayashi, Miriam Gullo, Gokhan Senturk, Stefania Di Costanzo, Shinji C Nagasaki, Samuel L Pfaff

bioRxiv· March 2023

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Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity.
Luis F Martins, Ilaria Brambilla, Alessia Motta, Stefano de Pretis, Ganesh Parameshwar Bhat, Samuel L Pfaff

Neuron· December 2022

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Spinal premotor interneurons controlling antagonistic muscles are spatially intermingled.
Remi Ronzano, Sophie Skarlatou, Bianca K Barriga, B Anne Bannatyne, Gardave Singh Bhumbra, Samuel L Pfaff

Elife· December 2022

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Precision spinal gene delivery-induced functional switch in nociceptive neurons reverses neuropathic pain.
Takahiro Tadokoro, Mariana Bravo-Hernandez, Kirill Agashkov, Yoshiomi Kobayashi, Oleksandr Platoshyn, Samuel L Pfaff

Mol Ther· August 2022

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Detecting microRNA-mediated gene regulatory effects in murine neuronal subpopulations.
Neal D Amin, Gokhan Senturk, Marito Hayashi, Shawn P Driscoll, Samuel L Pfaff

STAR Protoc· March 2022

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A hidden threshold in motor neuron gene networks revealed by modulation of miR-218 dose.
Neal D Amin, Gokhan Senturk, Giancarlo Costaguta, Shawn Driscoll, Brendan O'Leary, Samuel L Pfaff

Neuron· October 2021

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Conserved genetic signatures parcellate cardinal spinal neuron classes into local and projection subsets.
Peter J Osseward, Neal D Amin, Jeffrey D Moore, Benjamin A Temple, Bianca K Barriga, Samuel L Pfaff

Science· April 2021

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Author Correction: Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.
Andrew S Mendiola, Jae Kyu Ryu, Sophia Bardehle, Anke Meyer-Franke, Kenny Kean-Hooi Ang, Samuel J Pfaff

Nat Immunol· September 2020

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Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.
Andrew S Mendiola, Jae Kyu Ryu, Sophia Bardehle, Anke Meyer-Franke, Kenny Kean-Hooi Ang, Samuel J Pfaff

Nat Immunol· May 2020

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Spinal parenchymal occupation by neural stem cells after subpial delivery in adult immunodeficient rats.
Martin Marsala, Kota Kamizato, Takahiro Tadokoro, Michael Navarro, Stefan Juhas, Samuel Pfaff

Stem Cells Transl Med· February 2020

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Spinal subpial delivery of AAV9 enables widespread gene silencing and blocks motoneuron degeneration in ALS.
Mariana Bravo-Hernandez, Takahiro Tadokoro, Michael R Navarro, Oleksandr Platoshyn, Yoshiomi Kobayashi, Samuel L Pfaff

Nat Med· January 2020

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Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology.
Irit Reichenstein, Chen Eitan, Sandra Diaz-Garcia, Guy Haim, Iddo Magen, Samuel L Pfaff

Sci Transl Med· December 2019

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Cell type and circuit modules in the spinal cord.
Peter J Osseward, Samuel L Pfaff

Curr Opin Neurobiol· June 2019

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p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts.
Dario Bonanomi, Fabiola Valenza, Onanong Chivatakarn, Matthew J Sternfeld, Shawn P Driscoll, Samuel L Pfaff

Neuron· May 2019

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A scalable solution for isolating human multipotent clinical-grade neural stem cells from ES precursors.
Dasa Bohaciakova, Marian Hruska-Plochan, Rachel Tsunemoto, Wesley D Gifford, Shawn P Driscoll, Samuel L Pfaff

Stem Cell Res Ther· March 2019

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Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration.
Jae Kyu Ryu, Victoria A Rafalski, Anke Meyer-Franke, Ryan A Adams, Suresh B Poda, Samuel J Pfaff

Nat Immunol· November 2018

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Primary deuterium kinetic isotope effects prolong drug release and polymer biodegradation in a drug delivery system.
Brian R Hearn, Shaun D Fontaine, Samuel J Pfaff, Eric L Schneider, Jeff Henise

J Control Release· May 2018

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Survival of syngeneic and allogeneic iPSC-derived neural precursors after spinal grafting in minipigs.
Jan Strnadel, Cassiano Carromeu, Cedric Bardy, Michael Navarro, Oleksandr Platoshyn, Samuel L Pfaff

Sci Transl Med· May 2018

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