Publications by authors named "Sarah Spain"

Claim this Profile
T
Transcriptomic effects of rs4845604, an IBD and allergy-associated RORC variant, in stimulated ex vivo CD4+ T cells.
Paul A Wilson, Sara Santos Franco, Liu He, Nicholas W Galwey, Jackie Meakin, Sarah L Spain

PLoS One· November 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk.
Jennie G Pouget, , Buhm Han, Yang Wu, Emmanuel Mignot, Sarah Spain

Hum Mol Genet· October 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genomic atlas of the human plasma proteome.
Benjamin B Sun, Joseph C Maranville, James E Peters, David Stacey, James R Staley, Sarah L Spain

Nature· June 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling.
Nick Dand, Sören Mucha, Lam C Tsoi, Satveer K Mahil, Philip E Stuart, Sarah L Spain

Hum Mol Genet· November 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fine-mapping inflammatory bowel disease loci to single-variant resolution.
Hailiang Huang, Ming Fang, Luke Jostins, Maša Umićević Mirkov, Gabrielle Boucher, Sarah L Spain

Nature· July 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genome-Wide Association Studies Suggest Limited Immune Gene Enrichment in Schizophrenia Compared to 5 Autoimmune Diseases.
Jennie G Pouget, Vanessa F Gonçalves, , Sarah L Spain, Hilary K Finucane

Schizophr Bull· September 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
David Ellinghaus, Luke Jostins, Sarah L Spain, Adrian Cortes, Jörn Bethune

Nat Genet· May 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Strategies for fine-mapping complex traits.
Sarah L Spain, Jeffrey C Barrett

Hum Mol Genet· October 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Do Genetic Susceptibility Variants Associate with Disease Severity in Early Active Rheumatoid Arthritis?
Ian C Scott, Frühling Rijsdijk, Jemma Walker, Jelmar Quist, Sarah L Spain

J Rheumatol· July 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci.
Lam C Tsoi, Sarah L Spain, Eva Ellinghaus, Philip E Stuart, Francesca Capon

Nat Commun· May 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes.
Natalie J Prescott, Benjamin Lehne, Kristina Stone, James C Lee, Kirstin Taylor, Sarah L Spain

PLoS Genet· February 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An in-depth characterization of the major psoriasis susceptibility locus identifies candidate susceptibility alleles within an HLA-C enhancer element.
Alex Clop, Anna Bertoni, Sarah L Spain, Michael A Simpson, Venu Pullabhatla

PLoS One· April 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Investigating the genetic variation underlying episodicity in major depressive disorder: suggestive evidence for a bipolar contribution.
Panagiotis Ferentinos, Margarita Rivera, Marcus Ising, Sarah L Spain, Sarah Cohen-Woods

J Affect Disord· February 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas.
Claire Palles, Jean-Baptiste Cazier, Kimberley M Howarth, Enric Domingo, Angela M Jones, Sarah L Spain

Nat Genet· February 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis.
Jo Knight, Sarah L Spain, Francesca Capon, Adrian Hayday, Frank O Nestle

Hum Mol Genet· December 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.
Lam C Tsoi, Sarah L Spain, Jo Knight, Eva Ellinghaus, Philip E Stuart

Nat Genet· December 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Luke Jostins, Stephan Ripke, Rinse K Weersma, Richard H Duerr, Dermot P McGovern, Sarah L Spain

Nature· November 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
Malcolm G Dunlop, Sara E Dobbins, Susan Mary Farrington, Angela M Jones, Claire Palles, Sarah Spain

Nat Genet· May 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13.
Sarah L Spain, Luis G Carvajal-Carmona, Kimberley M Howarth, Angela M Jones, Zhan Su

Hum Mol Genet· February 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis.
Alexandros Onoufriadis, Michael A Simpson, Andrew E Pink, Paola Di Meglio, Catherine H Smith, Sarah L Spain

Am J Hum Genet· September 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.
Richard S Houlston, Jeremy Cheadle, Sara E Dobbins, Albert Tenesa, Angela M Jones, Sarah L Spain

Nat Genet· November 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Colorectal cancer risk is not associated with increased levels of homozygosity in a population from the United Kingdom.
Sarah L Spain, Jean-Baptiste Cazier, , Richard Houlston, Luis Carvajal-Carmona

Cancer Res· September 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A mitotic recombination map proximal to the APC locus on chromosome 5q and assessment of influences on colorectal cancer risk.
Kimberley Howarth, Susanna Ranta, Eitan Winter, Ana Teixeira, Helmut Schaschl, Sarah Spain

BMC Med Genet· June 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Common variation at the adiponectin locus is not associated with colorectal cancer risk in the UK.
Luis G Carvajal-Carmona, Sarah Spain, , David Kerr, Richard Houlston

Hum Mol Genet· May 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.

Nat Genet· December 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis