Publications by authors named "Sarah Tronnes"

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Discovery of potent and selective inhibitors of human NLRP3 with a novel mechanism of action.
Kevin Wilhelmsen, Aditi Deshpande, Sarah Tronnes, Maitriyee Mahanta, Matthew Banicki

J Exp Med· November 2025

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The discovery of novel and potent indazole NLRP3 inhibitors enabled by DNA-encoded library screening.
George Hartman, Paul Humphries, Robert Hughes, Andrew Ho, Rusty Montgomery, Sarah Tronnes

Bioorg Med Chem Lett· April 2024

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Glial-derived mitochondrial signals affect neuronal proteostasis and aging.
Raz Bar-Ziv, Naibedya Dutta, Adam Hruby, Edward Sukarto, Maxim Averbukh, Sarah U Tronnes

Sci Adv· October 2023

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Glial-derived mitochondrial signals impact neuronal proteostasis and aging.
Raz Bar-Ziv, Naibedya Dutta, Adam Hruby, Edward Sukarto, Maxim Averbukh, Sarah U Tronnes

bioRxiv· August 2023

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Glia of coordinate a protective organismal heat shock response independent of the neuronal thermosensory circuit.
Holly K Gildea, Phillip A Frankino, Sarah U Tronnes, Corinne L Pender, Jenni Durieux

Sci Adv· December 2022

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Divergent Nodes of Non-autonomous UPR Signaling through Serotonergic and Dopaminergic Neurons.
Ryo Higuchi-Sanabria, Jenni Durieux, Naame Kelet, Stefan Homentcovschi, Mattias de Los Rios Rogers, Sarah U Tronnes

Cell Rep· December 2020

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Lysosomal recycling of amino acids affects ER quality control.
Ryo Higuchi-Sanabria, Koning Shen, Naame Kelet, Phillip A Frankino, Jenni Durieux, Sarah U Tronnes

Sci Adv· June 2020

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UPR promotes lipophagy independent of chaperones to extend life span.
Joseph R Daniele, Ryo Higuchi-Sanabria, Jenni Durieux, Samira Monshietehadi, Vidhya Ramachandran, Sarah U Tronnes

Sci Adv· January 2020

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Four glial cells regulate ER stress resistance and longevity via neuropeptide signaling in .
Ashley E Frakes, Melissa G Metcalf, Sarah U Tronnes, Raz Bar-Ziv, Jenni Durieux

Science· January 2020

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Spatial regulation of the actin cytoskeleton by HSF-1 during aging.
Ryo Higuchi-Sanabria, Joseph W Paul, Jenni Durieux, Camila Benitez, Phillip A Frankino, Sarah U Tronnes

Mol Biol Cell· October 2018

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A Futile Battle? Protein Quality Control and the Stress of Aging.
Ryo Higuchi-Sanabria, Phillip Andrew Frankino, Joseph West Paul, Sarah Uhlein Tronnes, Andrew Dillin

Dev Cell· January 2018

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Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity.
Carsten Merkwirth, Virginija Jovaisaite, Jenni Durieux, Olli Matilainen, Sabine D Jordan, Sarah U Tronnes

Cell· May 2016

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