Publications by authors named "Satoshi Shuto"

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Design and Synthesis of Cyclopropane Congeners of Resolvin E2 with Azidopropoxy Chain toward a Chemical Tool for Probing the Anti-inflammatory Activity.
Hayato Fukuda, Kotaro Matsubara, Ayaka Hamaguchi, Hina Nishikoori, Mayu Shinohara, Satoshi Shuto

J Org Chem· December 2025

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Highly Selective Julia-Kocienski Olefination Using -Sulfonylimines and Its Mechanistic Insights from DFT Calculations.
Takuma Chizaki, Koichi Fujiwara, Junko Fujimoto, Tetsuo Narumi, Satoshi Shuto

Org Lett· March 2025

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Identification of BAY61-3606 Derivatives With Improved Activity in Splicing Modulation That Induces Inclusion of Cassette Exons Similar to the Splicing Factor 3B Subunit 1 Mutation.
Takanori Matsumaru, Toshiki Iwamatsu, Kana Ishigami, Makoto Inai, Wataru Kanto, Satoshi Shuto

Chem Biol Drug Des· October 2024

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Development of Conformationally Restricted Negamycin Derivatives for Potent Readthrough Activity.
Noriko Omura, Akihiro Taguchi, Tomoki Kuwahara, Keisuke Hamada, Mizuki Watanabe, Satoshi Shuto

ACS Med Chem Lett· December 2023

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Individual resolvin E family members work distinctly and in a coordinated manner in the resolution of inflammation.
Ayaka Hamaguchi, Hayato Fukuda, Koichi Fujiwara, Tomofumi Harada, Keijo Fukushima, Satoshi Shuto

Prostaglandins Other Lipid Mediat· October 2023

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Delivering mRNA to Secondary Lymphoid Tissues by Phosphatidylserine-Loaded Lipid Nanoparticles.
Masaki Gomi, Yu Sakurai, Minami Sato, Hiroki Tanaka, Yumi Miyatake, Satoshi Shuto

Adv Healthc Mater· April 2023

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Intranasal Administration of Resolvin E1 Produces Antidepressant-Like Effects via BDNF/VEGF-mTORC1 Signaling in the Medial Prefrontal Cortex.
Satoshi Deyama, Shun Aoki, Rinako Sugie, Hayato Fukuda, Satoshi Shuto

Neurotherapeutics· March 2023

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Helix-forming aliphatic homo-δ-peptide foldamers based on the conformational restriction effects of cyclopropane.
Makoto Nagata, Mizuki Watanabe, Ryohei Doi, Mai Uemura, Nanase Ochiai, Satoshi Shuto

Org Biomol Chem· February 2023

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Two oxytocin analogs, N-(p-fluorobenzyl) glycine and N-(3-hydroxypropyl) glycine, induce uterine contractions ex vivo in ways that differ from that of oxytocin.
Stanislav M Cherepanov, Teruko Yuhi, Takashi Iizuka, Takashi Hosono, Masanori Ono, Satoshi Shuto

PLoS One· February 2023

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Development of potent non-acylhydrazone inhibitors of intestinal sodium-dependent phosphate transport protein 2b (NaPi2b).
Michihiro Maemoto, Yuuki Hirata, Shintaro Hosoe, Jun Ouchi, Masako Uchii, Satoshi Shuto

Bioorg Med Chem· October 2022

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Design and Synthesis of Cyclopropane Congeners of Resolvin E3, an Endogenous Pro-Resolving Lipid Mediator, as Its Stable Equivalents.
Shota Arai, Koichi Fujiwara, Masahiro Kojima, Haruka Aoki-Saito, Masakiyo Yatomi, Satoshi Shuto

J Org Chem· August 2022

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Oxytocin Dynamics in the Body and Brain Regulated by the Receptor for Advanced Glycation End-Products, CD38, CD157, and Nicotinamide Riboside.
Haruhiro Higashida, Kazumi Furuhara, Olga Lopatina, Maria Gerasimenko, Osamu Hori, Satoshi Shuto

Front Neurosci· July 2022

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Synthesis of γ-Aminobutyric Acid (GABA) Analogues Conformationally Restricted by Bicyclo[3.1.0]hexane/hexene or [4.1.0]Heptane/heptene Backbones as Potent Betaine/GABA Transporter Inhibitors.
Keisuke Mitsui, Maria E K Lie, Naoki Saito, Koichi Fujiwara, Mizuki Watanabe, Satoshi Shuto

Org Lett· June 2022

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Resolvin E3 ameliorates high-fat diet-induced insulin resistance via the phosphatidylinositol-3-kinase/Akt signaling pathway in adipocytes.
Tomohiko Shimizu, Tsugumichi Saito, Haruka Aoki-Saito, Shuichi Okada, Hiroyuki Ikeda, Satoshi Shuto

FASEB J· March 2022

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The antidepressant-like effect of resolvin E1 in repeated prednisolone-induced depression model mice.
Shun Aoki, Satoshi Deyama, Rinako Sugie, Kohei Ishimura, Hayato Fukuda, Satoshi Shuto

Behav Brain Res· February 2022

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Discovery of Gut-Restricted Small-Molecule Inhibitors of Intestinal Sodium-Dependent Phosphate Transport Protein 2b (NaPi2b) for the Treatment of Hyperphosphatemia.
Michihiro Maemoto, Yuuki Hirata, Shintaro Hosoe, Jun Ouchi, Kazuya Narushima, Satoshi Shuto

J Med Chem· February 2022

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Resolvin E1 Attenuates Chronic Pain-Induced Depression-Like Behavior in Mice: Possible Involvement of Chemerin Receptor ChemR23.
Hiroe Suzuki, Takahisa Otsuka, Natsuko Hitora-Imamura, Kohei Ishimura, Hayato Fukuda, Satoshi Shuto

Biol Pharm Bull· January 2022

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Visualized and Quantitative Conformational Analysis of Peptidomimetics.
Hajime Takashima, Atsushi Yoshimori, Eiji Honda, Tomonori Taguri, Jun Ozawa, Satoshi Shuto

ACS Omega· October 2021

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Design, Synthesis, and Monoamine Oxidase Inhibitory Activity of (+)-Cinchonaminone and Its Simplified Derivatives.
Yuta Sato, Naoko Oyobe, Takao Ogawa, Sayo Suzuki, Hiroshi Aoyama, Satoshi Shuto

ACS Med Chem Lett· September 2021

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Molecular Determinants and Pharmacological Analysis for a Class of Competitive Non-transported Bicyclic Inhibitors of the Betaine/GABA Transporter BGT1.
Stefanie Kickinger, Maria E K Lie, Akihiro Suemasa, Anas Al-Khawaja, Koichi Fujiwara, Satoshi Shuto

Front Chem· September 2021

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Toxicokinetics of methylmercury in diabetic KK-Ay mice and C57BL/6 mice.
Megumi Yamamoto, Rie Yanagisawa, Atsushi Sakai, Masaki Mogi, Satoshi Shuto

J Appl Toxicol· June 2021

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Structure-activity Relationship of Indomethacin Derivatives as IDO1 Inhibitors.
Tohru Obata, Sara Shiratani, Tomomi Nada, Yayoi Kasaya, Mitsuhiro Arisawa, Satoshi Shuto

Anticancer Res· May 2021

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Structure, solubility, and permeability relationships in a diverse middle molecule library.
Hiroyuki Miyachi, Kayoko Kanamitsu, Mayumi Ishii, Eri Watanabe, Akira Katsuyama, Satoshi Shuto

Bioorg Med Chem Lett· April 2021

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Discovery of 6-Oxo-4-phenyl-hexanoic acid derivatives as RORγt inverse agonists showing favorable ADME profile.
Ryota Nakajima, Hiroyuki Oono, Keiko Kumazawa, Tomohide Ida, Jun Hirata, Satoshi Shuto

Bioorg Med Chem Lett· March 2021

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Synthesis of Resolvin E1 and Its Conformationally Restricted Cyclopropane Congeners with Potent Anti-Inflammatory Effect.
Kohei Ishimura, Hayato Fukuda, Koichi Fujiwara, Ryuta Muromoto, Koki Hirashima, Satoshi Shuto

ACS Med Chem Lett· February 2021

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