Publications by authors named "Sha Mi"

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A
American literature news narration based on computer web technology.
Juan Liu, Sha Mi

PLoS One· October 2023

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Comparison of the Design Space of Products with Different Initial Saturation.
Chun Luo, Zhiqiang Liu, Sha Mi, Lingling Cai, Zezong Zhang

J Pharm Sci· March 2022

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Discovery of Potent Selective Nonzinc Binding Autotaxin Inhibitor BIO-32546.
Bin Ma, Lei Zhang, Lihong Sun, Zhili Xin, Gnanasambandam Kumaravel, Sha Mi

ACS Med Chem Lett· July 2021

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Functional activity of anti-LINGO-1 antibody opicinumab requires target engagement at a secondary binding site.
Karl J M Hanf, Joseph W Arndt, YuTing Liu, Bang Jian Gong, Mia Rushe, Ramiro Massol, Benjamin Smith, Sha Mi

MAbs· February 2021

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Safety and efficacy of opicinumab in patients with relapsing multiple sclerosis (SYNERGY): a randomised, placebo-controlled, phase 2 trial.
Diego Cadavid, Michelle Mellion, Raymond Hupperts, Keith R Edwards, Peter A Calabresi, Sha Mi

Lancet Neurol· September 2019

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Anti-LINGO-1 has no detectable immunomodulatory effects in preclinical and phase 1 studies.
Ann Ranger, Soma Ray, Suzanne Szak, Andrea Dearth, Norm Allaire, Sha Mi

Neurol Neuroimmunol Neuroinflamm· January 2018

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LINGO-1 Regulates Oligodendrocyte Differentiation through the Cytoplasmic Gelsolin Signaling Pathway.
Zhaohui Shao, Xinhua Lee, Guanrong Huang, Guoqing Sheng, Christopher E Henderson, Sha Mi

J Neurosci· March 2017

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Blocking LINGO-1 in vivo reduces degeneration and enhances regeneration of the optic nerve.
Melissa M Gresle, Yaou Liu, Trevor J Kilpatrick, Dennis Kemper, Qi-Zhu Wu, Sha Mi

Mult Scler J Exp Transl Clin· April 2016

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I
Inhibition of LINGO-1 promotes functional recovery after experimental spinal cord demyelination.
Yongjie Zhang, Yi Ping Zhang, Blake Pepinsky, Guanrong Huang, Lisa B E Shields, Sha Mi

Exp Neurol· April 2015

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Structure of the LINGO-1-anti-LINGO-1 Li81 antibody complex provides insights into the biology of LINGO-1 and the mechanism of action of the antibody therapy.
R Blake Pepinsky, Joseph W Arndt, Chao Quan, Yan Gao, Omar Quintero-Monzon, Sha Mi

J Pharmacol Exp Ther· July 2014

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LINGO-1 regulates oligodendrocyte differentiation by inhibiting ErbB2 translocation and activation in lipid rafts.
Xinhua Lee, Zhaohui Shao, Guoqing Sheng, Blake Pepinsky, Sha Mi

Mol Cell Neurosci· May 2014

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Blocking LINGO-1 as a therapy to promote CNS repair: from concept to the clinic.
Sha Mi, R Blake Pepinsky, Diego Cadavid

CNS Drugs· July 2013

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Role of transmembrane semaphorin Sema6A in oligodendrocyte differentiation and myelination.
Frédéric Bernard, Caroline Moreau-Fauvarque, Céline Heitz-Marchaland, Yvrick Zagar, Laura Dumas, Sha Mi

Glia· October 2012

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Exposure levels of anti-LINGO-1 Li81 antibody in the central nervous system and dose-efficacy relationships in rat spinal cord remyelination models after systemic administration.
R Blake Pepinsky, Zhaohui Shao, Benxiu Ji, Qin Wang, Gym Meng, Sha Mi

J Pharmacol Exp Ther· November 2011

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S
Sphingosine 1-phosphate receptor modulator fingolimod (FTY720) does not promote remyelination in vivo.
Yinghui Hu, Xinhua Lee, Benxiu Ji, Kevin Guckian, Daniel Apicco, Robert H Miller, Sha Mi

Mol Cell Neurosci· September 2011

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Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination.
Sha Mi, Xinhua Lee, Yinghui Hu, Benxiu Ji, Zhaohui Shao, Robert H Miller

Nat Med· July 2011

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Oligodendrocyte differentiation and myelination defects in OMgp null mice.
Xinhua Lee, Yinghui Hu, Yiping Zhang, Zhongshu Yang, Zhaohui Shao, Robert H Miller, Sha Mi

Mol Cell Neurosci· April 2011

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Production of a PEGylated Fab' of the anti-LINGO-1 Li33 antibody and assessment of its biochemical and functional properties in vitro and in a rat model of remyelination.
R Blake Pepinsky, Lee Walus, Zhaohui Shao, Benxiu Ji, Sheng Gu, Sha Mi

Bioconjug Chem· February 2011

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Characterization of trisulfide modification in antibodies.
Sheng Gu, Dingyi Wen, Paul H Weinreb, Yaping Sun, Lihe Zhang, Rashmi Kshirsagar, Sha Mi

Anal Biochem· May 2010

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Improving the solubility of anti-LINGO-1 monoclonal antibody Li33 by isotype switching and targeted mutagenesis.
R Blake Pepinsky, Laura Silvian, Steven A Berkowitz, Graham Farrington, Alexey Lugovskoy, Sha Mi

Protein Sci· May 2010

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LINGO-1 negatively regulates TrkB phosphorylation after ocular hypertension.
Qing-Ling Fu, Bing Hu, Xin Li, Zhaohui Shao, Jian-Bo Shi, Sha Mi

Eur J Neurosci· March 2010

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Overexpression of GAP-43 modifies the distribution of the receptors for myelin-associated growth-inhibitory proteins in injured Purkinje axons.
Simona Foscarin, Sara Gianola, Daniela Carulli, Pietro Fazzari, Sha Mi

Eur J Neurosci· November 2009

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Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells.
Sha Mi, Robert H Miller, Wei Tang, Xinhua Lee, Bing Hu, Steven Miklasz

Ann Neurol· March 2009

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Assessment of functional recovery and axonal sprouting in oligodendrocyte-myelin glycoprotein (OMgp) null mice after spinal cord injury.
Benxiu Ji, Lauren C Case, Kai Liu, Zhaohui Shao, Xinhua Lee, Sha Mi

Mol Cell Neurosci· October 2008

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LINGO-1 antagonists as therapy for multiple sclerosis: in vitro and in vivo evidence.
Richard A Rudick, Sha Mi, Alfred W Sandrock

Expert Opin Biol Ther· October 2008

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