Publications by authors named "Sharon Lu"

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Transdiagnostic clustering of self-schema from self-referential judgements identifies subtypes of healthy personality and depression.
Geoffrey Chern-Yee Tan, Ziying Wang, Ethel Siew Ee Tan, Rachel Jing Min Ong, Pei En Ooi, Sharon Huixian Lu, Christopher Lee Asplund

Front Neuroinform· September 2025

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Correction: Transdiagnostic clustering of self-schema from self-referential judgements identifies subtypes of healthy personality and depression.
Geoffrey Chern-Yee Tan, Ziying Wang, Ethel Siew Ee Tan, Rachel Jing Min Ong, Pei En Ooi, Sharon Huixian Lu, Christopher Lee Asplund

Front Neuroinform· September 2025

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Dostarlimab, an anti-programmed death-1 monoclonal antibody, does not cause QT prolongation in patients with solid tumours: A concentration-QT analysis.
Mita Kuchimanchi, Christine Dabrowski, Sharon Lu, Murad Melhem

Br J Clin Pharmacol· July 2023

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Comparative analysis of PD-1 target engagement of dostarlimab and pembrolizumab in advanced solid tumors using ex vivo IL-2 stimulation data.
Daren Austin, Murad Melhem, Yash Gandhi, Sharon Lu, Sandra Visser

CPT Pharmacometrics Syst Pharmacol· January 2023

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Population pharmacokinetics and exposure-response of anti-programmed cell death protein-1 monoclonal antibody dostarlimab in advanced solid tumours.
Murad Melhem, Eva Hanze, Sharon Lu, Oskar Alskär, Sandra Visser

Br J Clin Pharmacol· September 2022

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Positive mental health in psychotherapy: a qualitative study from psychotherapists' perspectives.
Sherilyn Chang, Rajeswari Sambasivam, Esmond Seow, Mythily Subramaniam, Hanita Ashok Assudani, Sharon Huixian Lu

BMC Psychol· April 2022

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IOLite: phase 1b trial of doublet/triplet combinations of dostarlimab with niraparib, carboplatin-paclitaxel, with or without bevacizumab in patients with advanced cancer.
Timothy A Yap, Alberto Bessudo, Erika Hamilton, Jasgit Sachdev, Manish R Patel, Sharon Lu

J Immunother Cancer· March 2022

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Preclinical characterization of dostarlimab, a therapeutic anti-PD-1 antibody with potent activity to enhance immune function in in vitro cellular assays and in vivo animal models.
Sujatha Kumar, Srimoyee Ghosh, Geeta Sharma, Zebin Wang, Marilyn R Kehry, Sharon Lu, Shouqi Luo

MAbs· January 2022

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JASPER: Phase 2 trial of first-line niraparib plus pembrolizumab in patients with advanced non-small cell lung cancer.
Suresh S Ramalingam, Eddie Thara, Mark M Awad, Afshin Dowlati, Basir Haque, Sharon Lu

Cancer· January 2022

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Safety, antitumor activity, and pharmacokinetics of dostarlimab, an anti-PD-1, in patients with advanced solid tumors: a dose-escalation phase 1 trial.
Amita Patnaik, Glen J Weiss, Drew W Rasco, Lisa Blaydorn, Amy Mirabella, Sharon Lu

Cancer Chemother Pharmacol· January 2022

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"We Are All Trying to Find a Way to Help Ourselves": A Look at Self-Help Strategies Among Psychotherapy Clients.
Sherilyn Chang, Rajeswari Sambasivam, Esmond Seow, Geoffrey Chern-Yee Tan, Sharon Huixian Lu

Front Psychol· October 2021

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An Integrated Analysis of Dostarlimab Immunogenicity.
Sharon Lu, Ronald R Bowsher, Amanda Clancy, Amy Rosen, Mingxuan Zhang

AAPS J· July 2021

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A Randomised Controlled Trial of Clinician-Guided Internet-Based Cognitive Behavioural Therapy for Depressed Patients in Singapore.
Sharon H X Lu, Hanita A Assudani, Tammie R R Kwek, Shaun W H Ng, Trisha E L Teoh

Front Psychol· July 2021

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Salvage Cryoablation for Radiorecurrent Prostate Cancer: Initial Experience at a Regional Health Care System.
Seena Safavy, Ramzi B Jabaji, Sharon M Lu, Jeff M Slezak, Harry A Cosmatos

Perm J· February 2020

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A phase 1, open-label, dose-escalation trial of oral TSR-011 in patients with advanced solid tumours and lymphomas.
Chia-Chi Lin, Hendrik-Tobias Arkenau, Sharon Lu, Jasgit Sachdev, Javier de Castro Carpeño

Br J Cancer· July 2019

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Pharmacokinetic Interactions of Rolapitant With Cytochrome P450 3A Substrates in Healthy Subjects.
Xiaodong Wang, Jing Wang, Sujata Arora, Lorraine Hughes, Jennifer Christensen, Sharon Lu

J Clin Pharmacol· April 2019

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Effects of rolapitant administered orally on the pharmacokinetics of dextromethorphan (CYP2D6), tolbutamide (CYP2C9), omeprazole (CYP2C19), efavirenz (CYP2B6), and repaglinide (CYP2C8) in healthy subjects.
Jing Wang, Zhi-Yi Zhang, Sharon Lu, Dan Powers, Vikram Kansra

Support Care Cancer· March 2019

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Pharmacokinetics, Safety, and Tolerability of Rolapitant Administered Intravenously Following Single Ascending and Multiple Ascending Doses in Healthy Subjects.
Xiaodong Wang, Zhi-Yi Zhang, Jing Wang, Dan Powers, Sujata Arora, Sharon Lu

Clin Pharmacol Drug Dev· February 2019

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An Open-Label, Randomized, Pivotal Bioequivalence Study of Oral Rolapitant.
Zhi-Yi Zhang, Jing Wang, Sujata Arora, Sharon Lu, Dan Powers

Clin Pharmacol Drug Dev· February 2019

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Effects of Rolapitant Administered Intravenously on the Pharmacokinetics of a Modified Cooperstown Cocktail (Midazolam, Omeprazole, Warfarin, Caffeine, and Dextromethorphan) in Healthy Subjects.
Xiaodong Wang, Zhi-Yi Zhang, Sujata Arora, Jing Wang, Sharon Lu

J Clin Pharmacol· August 2018

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Pharmacokinetics of Rolapitant in Patients With Mild to Moderate Hepatic Impairment.
Jing Wang, Xiaodong Wang, Zhi-Yi Zhang, Sujata Arora, Sharon Lu

J Clin Pharmacol· May 2018

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Effects of Rolapitant Administered Intravenously or Orally on the Pharmacokinetics of Digoxin (P-glycoprotein Substrate) and Sulfasalazine (Breast Cancer Resistance Protein Substrate) in Healthy Volunteers.
Xiaodong Wang, Zhi-Yi Zhang, Sujata Arora, Lorraine Hughes, Jing Wang, Sharon Lu

J Clin Pharmacol· February 2018

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Bioequivalence of Intravenous and Oral Rolapitant: Results From a Randomized, Open-Label Pivotal Study.
Xiaodong Wang, Zhi-Yi Zhang, Daniel Powers, Jing Wang, Sharon Lu

J Clin Pharmacol· December 2017

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BORC Regulates the Axonal Transport of Synaptic Vesicle Precursors by Activating ARL-8.
Shinsuke Niwa, Li Tao, Sharon Y Lu, Gerald M Liew, Wei Feng

Curr Biol· September 2017

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Pathologic response after neoadjuvant chemotherapy predicts locoregional control in patients with triple negative breast cancer.
Victor E Chen, Erin F Gillespie, Kaveh Zakeri, James D Murphy, Catheryn M Yashar, Sharon Lu

Adv Radiat Oncol· February 2017

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