Publications by authors named "Shefali Setia-Verma"

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Expanding the genetic landscape of endometriosis: Integrative -omics analyses implicate key genes and pathways in a multi-ancestry study of over one million women.
Lindsay A Guare, Jagyashila Das, Lannawill Caruth, Ananya Rajagopalan, Alexis T Akerele, Shefali Setia-Verma

Res Sq· December 2025

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An African ancestry-specific nonsense variant in CD36 is associated with a higher risk of dilated cardiomyopathy.
Jennifer E Huffman, Liam Gaziano, Zeina R Al Sayed, Renae L Judy, Laura M Raffield

Nat Genet· November 2025

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Developing Predictive Models for Periodontitis Progression Using Artificial Intelligence: A Longitudinal Cohort Study.
Camila Pinheiro Furquim, Lannawill Caruth, Ganesh Chandrasekaran, Andrew Cucchiara, Michael J Kallan

J Clin Periodontol· October 2025

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Multimodal Prediction of Primary Open-Angle Glaucoma Using Polygenic Risk Scores and Clinical Features in a High-Risk African Ancestry Cohort.
Yan Zhu, Aude Benigne Ikuzwe Sindikubwabo, Yuki Bradford, Rebecca Salowe, Lannawill Caruth, Shefali Setia-Verma

medRxiv· October 2025

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Endophenotype Guided Genome-Wide Association Study to Enhance Genetic Risk Prediction of Primary Open-Angle Glaucoma in African Ancestry Populations.
Aude Benigne Ikuzwe Sindikubwabo, Lannawill Caruth, Yan Zhu, Yuki Bradford, Rebecca Salowe, Shefali Setia-Verma

medRxiv· October 2025

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Disease-associated Kv1.3 Variants are Energy Compromised with Impaired Nascent Chain Folding.
Aaron Sykes, Lannawill Caruth, Sophia Gross, Shefali Setia Verma, Toshinori Hoshi

J Mol Biol· September 2025

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Serum Protein Dynamics in Early Pregnancy Loss Management: Findings from the PreFaiR Trial.
Jagyashila Das, Sarah M Gutman, Arden McAllister, Mary Sammel, Courtney A Schreiber

Res Sq· September 2025

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DRIVE-KG: Enhancing variant-phenotype association discovery in understudied complex diseases using heterogeneous knowledge graphs.
Ananya Rajagopalan, Tram Anh Nguyen, Lindsay A Guare, Andre Luis Garao Rico, Rasika Venkatesh, Shefali Setia-Verma

medRxiv· August 2025

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Large-scale evaluation of proteomic and polygenic risk scores reveals complementary contributions to incident disease prediction.
Jakob Woerner, Thomas M Westbrook, Jaehyun Joo, Manu Shivakumar, Rasika Venkatesh, Shefali Setia-Verma

medRxiv· July 2025

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Disease-associated Kv1.3 variants are energy compromised with impaired nascent chain folding.
Aaron Sykes, Lannawill Caruth, Shefali Setia Verma, Toshinori Hoshi, Carol Deutsch

bioRxiv· February 2025

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Common tandem repeat variants associated with glaucoma risk in individuals of African ancestry.
Kenneth Pham, Roy Lee, Isabel Di Rosa, Rebecca Salowe, Fangming Jin, Shefali Setia-Verma

medRxiv· February 2025

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Social Determinants of Health and Lifestyle Risk Factors Modulate Genetic Susceptibility for Women's Health Outcomes.
Lindsay A Guare, Jagyashila Das, Lannawill Caruth, Shefali Setia-Verma

Pac Symp Biocomput· December 2024

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Expanding the genetic landscape of endometriosis: Integrative -omics analyses uncover key pathways from a multi-ancestry study of over 900,000 women.
Lindsay A Guare, Jagyashila Das, Lannawill Caruth, Ananya Rajagopalan, Alexis T Akerele, Shefali Setia-Verma

medRxiv· November 2024

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Multi-ancestry polygenic risk scores for venous thromboembolism.
Yon Ho Jee, Florian Thibord, Alicia Dominguez, Corriene Sept, Kristin Boulier

Hum Mol Genet· September 2024

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Enhancing genetic association power in endometriosis through unsupervised clustering of clinical subtypes identified from electronic health records.
Lindsay A Guare, Leigh Ann Humphrey, Margaret Rush, Meredith Pollie, James Jaworski, Shefali Setia-Verma

Res Sq· September 2024

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Genetic predictors of blood pressure traits are associated with preeclampsia.
Elizabeth A Jasper, Jacklyn N Hellwege, Joseph H Breeyear, Brenda Xiao, Gail P Jarvik

Sci Rep· July 2024

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Longitudinal method comparison: modeling polygenic risk for post-traumatic stress disorder over time in individuals of African and European ancestry.
Kristin Passero, Jennie G Noll, Shefali Setia Verma, Claire Selin, Molly A Hall

Front Genet· May 2024

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Enhancing Genetic Association Power in Endometriosis through Unsupervised Clustering of Clinical Subtypes Identified from Electronic Health Records.
Lindsay Guare, Leigh Ann Humphrey, Margaret Rush, Meredith Pollie, Yuan Luo, Shefali Setia-Verma

medRxiv· April 2024

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Multi-ancestry polygenic risk scores for venous thromboembolism.
Yon Ho Jee, Florian Thibord, Alicia Dominguez, Corriene Sept, Kristin Boulier

medRxiv· January 2024

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Gene Interactions in Human Disease Studies-Evidence Is Mounting.
Pankhuri Singhal, Shefali Setia Verma, Marylyn D Ritchie

Annu Rev Biomed Data Sci· August 2023

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Polygenic prediction of preeclampsia and gestational hypertension.
Michael C Honigberg, Buu Truong, Raiyan R Khan, Brenda Xiao, Laxmi Bhatta

Nat Med· June 2023

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Genome-Wide Association Study of Breast Density among Women of African Ancestry.
Shefali Setia Verma, Lindsay Guare, Sarah Ehsan, Aimilia Gastounioti, Gabrielle Scales

Cancers (Basel)· May 2023

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Multiancestry Genome-Wide Association Study of Aortic Stenosis Identifies Multiple Novel Loci in the Million Veteran Program.
Aeron M Small, Gina M Peloso, Jason Linefsky, Jayashri Aragam, Ashley Galloway, Shefali Setia-Verma

Circulation· March 2023

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Inference of Causal Relationships Between Genetic Risk Factors for Cardiometabolic Phenotypes and Female-Specific Health Conditions.
Brenda Xiao, Digna R Velez Edwards, Anastasia Lucas, Theodore Drivas, Kathryn Gray

J Am Heart Assoc· March 2023

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Genetic Predictors of Blood Pressure Traits are Associated with Preeclampsia.
Elizabeth A Jasper, Jacklyn N Hellwege, Joseph H Breeyear, Brenda Xiao, Gail P Jarvik

medRxiv· February 2023

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