Publications by authors named "Sheldon Hiebert"

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Discovery of BMS-986144, a Third-Generation, Pan-Genotype NS3/4A Protease Inhibitor for the Treatment of Hepatitis C Virus Infection.
Li-Qiang Sun, Eric Mull, Stanley D'Andrea, Barbara Zheng, Sheldon Hiebert

J Med Chem· December 2020

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Correction to "Total Synthesis of (-)-Sarain A".
Michael H Becker, Peter Chua, Robert Downham, Christopher J Douglas, Neil K Garg, Sheldon Hiebert

J Am Chem Soc· April 2018

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The discovery and optimization of naphthalene-linked P2-P4 Macrocycles as inhibitors of HCV NS3 protease.
Michael Bowsher, Sheldon Hiebert, Rongti Li, Alan X Wang, Jacques Friborg

Bioorg Med Chem Lett· January 2018

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4-Benzothiazole-7-hydroxyindolinyl diaryl ureas are potent P2Y1 antagonists with favorable pharmacokinetics: low clearance and small volume of distribution.
Jennifer X Qiao, Tammy C Wang, Sheldon Hiebert, Carol H Hu, William A Schumacher

ChemMedChem· October 2014

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Identification of 1-{2-[4-chloro-1'-(2,2-dimethylpropyl)-7-hydroxy-1,2-dihydrospiro[indole-3,4'-piperidine]-1-yl]phenyl}-3-{5-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl}urea, a potent, efficacious and orally bioavailable P2Y(1) antagonist as an antiplatelet agent.
Yoon T Jeon, Wu Yang, Jennifer X Qiao, Ling Li, Rejean Ruel, Sheldon Hiebert

Bioorg Med Chem Lett· March 2014

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Conformationally constrained ortho-anilino diaryl ureas: discovery of 1-(2-(1'-neopentylspiro[indoline-3,4'-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea, a potent, selective, and bioavailable P2Y1 antagonist.
Jennifer X Qiao, Tammy C Wang, Réjean Ruel, Carl Thibeault, Alexandre L'Heureux, Sheldon Hiebert

J Med Chem· November 2013

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Total synthesis of (+)-sarain A.
Michael H Becker, Peter Chua, Robert Downham, Christopher J Douglas, Neil K Garg, Sheldon Hiebert

J Am Chem Soc· October 2007

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Synthesis of all low-energy stereoisomers of the tris(pyrrolidinoindoline) alkaloid hodgkinsine and preliminary assessment of their antinociceptive activity.
Jeremy J Kodanko, Sheldon Hiebert, Emily A Peterson, Leonard Sung, Larry E Overman

J Org Chem· October 2007

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Total synthesis of (-)-sarain A.
Neil K Garg, Sheldon Hiebert, Larry E Overman

Angew Chem Int Ed Engl· April 2006

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Toward an enantioselective total synthesis of sarain A: construction of an advanced intermediate and rearrangement of the sarain A core under mild conditions.
Christopher J Douglas, Sheldon Hiebert, Larry E Overman

Org Lett· March 2005

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Scope of palladium-catalyzed alkylative ring opening.
Mark Lautens, Sheldon Hiebert

J Am Chem Soc· February 2004

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Transition metal-catalyzed enantioselective ring-opening reactions of oxabicyclic alkenes.
Mark Lautens, Keith Fagnou, Sheldon Hiebert

Acc Chem Res· January 2003

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Total synthesis of ionomycin using ring-opening strategies.
Mark Lautens, John T Colucci, Sheldon Hiebert, Nicholas D Smith, Giliane Bouchain

Org Lett· May 2002

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