Publications by authors named "Shigeru Ko"

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Electronic Patient-Reported Outcome System Implementation in Outpatient Cardiovascular Care: A Randomized Clinical Trial.
Shuhei Yamashita, Yoshinori Katsumata, Shun Kohsaka, Hiroki Kitakata, Yasuyuki Shiraishi, Koki Yamaoka, Tomohiko Ono, Shigeru B H Ko, Yuko Kitagawa

JAMA Netw Open· January 2025

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GRable Version 1.0: A Software Tool for Site-Specific Glycoform Analysis With Improved MS1-Based Glycopeptide Detection With Parallel Clustering and Confidence Evaluation With MS2 Information.
Chiaki Nagai-Okatani, Daisuke Tominaga, Azusa Tomioka, Hiroaki Sakaue, Norio Goda, Shigeru Ko

Mol Cell Proteomics· September 2024

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Ensemble detection of hand joint ankylosis and subluxation in radiographic images using deep neural networks.
Keisuke Izumi, Kanata Suzuki, Masahiro Hashimoto, Masahiro Jinzaki, Shigeru Ko, Yuko Kaneko

Sci Rep· April 2024

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ZSCAN4-binding motif-TGCACAC is conserved and enriched in CA/TG microsatellites in both mouse and human genomes.
Tomohiko Akiyama, Kei-Ichiro Ishiguro, Nana Chikazawa, Shigeru B H Ko, Masashi Yukawa, Minoru S H Ko

DNA Res· February 2024

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Detecting hand joint ankylosis and subluxation in radiographic images using deep learning: A step in the development of an automatic radiographic scoring system for joint destruction.
Keisuke Izumi, Kanata Suzuki, Masahiro Hashimoto, Toshio Endoh, Kentaro Doi, Shigeru Ko, Yuko Kaneko

PLoS One· February 2023

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Unbiased, comprehensive analysis of Japanese health checkup data reveals a protective effect of light to moderate alcohol consumption on lung function.
Kanako Makino, Ryoko Shimizu-Hirota, Norio Goda, Masahiro Hashimoto, Ichiro Kawada, Minoru Ko, Shigeru Ko

Sci Rep· August 2021

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Synthetic mRNA-based differentiation method enables early detection of Parkinson's phenotypes in neurons derived from Gaucher disease-induced pluripotent stem cells.
Tomohiko Akiyama, Saeko Sato, Shigeru B H Ko, Osamu Sano, Sho Sato, Minoru S H Ko

Stem Cells Transl Med· April 2021

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Generation and Profiling of 2,135 Human ESC Lines for the Systematic Analyses of Cell States Perturbed by Inducing Single Transcription Factors.
Yuhki Nakatake, Shigeru B H Ko, Alexei A Sharov, Shunichi Wakabayashi, Miyako Murakami, Miki Sakota, Saeko Sato, Noriko Ito, Misako Matsushita, Tomohiko Akiyama, Minoru S H Ko

Cell Rep· May 2020

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Induction of human pluripotent stem cells into kidney tissues by synthetic mRNAs encoding transcription factors.
Ken Hiratsuka, Toshiaki Monkawa, Tomohiko Akiyama, Yuhki Nakatake, Mayumi Oda, Saeko Sato, Shigeru B H Ko, Minoru S H Ko

Sci Rep· January 2019

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Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factors.
Hideomi Ida, Tomohiko Akiyama, Keiichiro Ishiguro, Sravan K Goparaju, Yuhki Nakatake, Saeko Sato, Yukihiro Yokoyama, Minoru S H Ko, Shigeru B H Ko

Stem Cell Res Ther· October 2018

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Efficient differentiation of human pluripotent stem cells into skeletal muscle cells by combining RNA-based MYOD1-expression and POU5F1-silencing.
Tomohiko Akiyama, Saeko Sato, Nana Chikazawa-Nohtomi, Atsumi Soma, Hiromi Kimura, Shigeru B H Ko, Minoru S H Ko

Sci Rep· January 2018

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SCODE: an efficient regulatory network inference algorithm from single-cell RNA-Seq during differentiation.
Hirotaka Matsumoto, Hisanori Kiryu, Chikara Furusawa, Minoru S H Ko, Shigeru B H Ko

Bioinformatics· August 2017

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Neural differentiation of human embryonic stem cells induced by the transgene-mediated overexpression of single transcription factors.
Misako Matsushita, Yuhki Nakatake, Itaru Arai, Keiji Ibata, Kazuhisa Kohda, Miyako Murakami, Miki Sakota, Shigeru B H Ko, Minoru S H Ko

Biochem Biophys Res Commun· August 2017

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Salt suppresses IFNγ inducible chemokines through the IFNγ-JAK1-STAT1 signaling pathway in proximal tubular cells.
Yohei Arai, Daiei Takahashi, Kenichi Asano, Masato Tanaka, Mayumi Oda, Shigeru B H Ko, Minoru S H Ko

Sci Rep· April 2017

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Epigenetic Manipulation Facilitates the Generation of Skeletal Muscle Cells from Pluripotent Stem Cells.
Tomohiko Akiyama, Shunichi Wakabayashi, Atsumi Soma, Saeko Sato, Yuhki Nakatake, Miyako Murakami, Miki Sakota, Shigeru B H Ko, Minoru S H Ko

Stem Cells Int· April 2017

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Bicarbonate-rich fluid secretion predicted by a computational model of guinea-pig pancreatic duct epithelium.
Makoto Yamaguchi, Martin C Steward, Kieran Smallbone, Yoshiro Sohma, Akiko Yamamoto, Shigeru B H Ko, Takaharu Kondo

J Physiol· March 2017

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Expression analysis of the endogenous Zscan4 locus and its coding proteins in mouse ES cells and preimplantation embryos.
Kei-Ichiro Ishiguro, Yuhki Nakatake, Nana Chikazawa-Nohtomi, Hiromi Kimura, Tomohiko Akiyama, Shigeru B H Ko, Minoru S H Ko

In Vitro Cell Dev Biol Anim· February 2017

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Zscan4 is expressed specifically during late meiotic prophase in both spermatogenesis and oogenesis.
Kei-Ichiro Ishiguro, Manuela Monti, Tomohiko Akiyama, Hiromi Kimura, Nana Chikazawa-Nohtomi, Miki Sakota, Saeko Sato, Shigeru B H Ko, Minoru S H Ko

In Vitro Cell Dev Biol Anim· February 2017

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Rapid differentiation of human pluripotent stem cells into functional neurons by mRNAs encoding transcription factors.
Sravan Kumar Goparaju, Kazuhisa Kohda, Keiji Ibata, Atsumi Soma, Yukhi Nakatake, Tomohiko Akiyama, Misako Matsushita, Miki Sakota, Shigeru B H Ko, Minoru S H Ko

Sci Rep· February 2017

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Identification of transcription factors that promote the differentiation of human pluripotent stem cells into lacrimal gland epithelium-like cells.
Masatoshi Hirayama, Shigeru B H Ko, Tetsuya Kawakita, Tomohiko Akiyama, Sravan K Goparaju, Miki Sakota, Minoru S H Ko

NPJ Aging Mech Dis· January 2017

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Transient ectopic expression of the histone demethylase JMJD3 accelerates the differentiation of human pluripotent stem cells.
Tomohiko Akiyama, Shunichi Wakabayashi, Atsumi Soma, Saeko Sato, Yuhki Nakatake, Miyako Murakami, Miki Sakota, Shigeru B H Ko, Minoru S H Ko

Development· October 2016

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Osteoprotegerin Regulates Pancreatic β-Cell Homeostasis upon Microbial Invasion.
Yukiko Kuroda, Kenta Maruyama, Hideki Fujii, Isamu Sugawara, Shigeru B H Ko, Koichi Matsuo

PLoS One· July 2016

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Transient bursts of Zscan4 expression are accompanied by the rapid derepression of heterochromatin in mouse embryonic stem cells.
Tomohiko Akiyama, Li Xin, Mayumi Oda, Alexei A Sharov, Misa Amano, Shigeru B H Ko, Minoru S H Ko

DNA Res· October 2015

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Functional characteristics of L1156F-CFTR associated with alcoholic chronic pancreatitis in Japanese.
Shiho Kondo, Kotoyo Fujiki, Shigeru B H Ko, Akiko Yamamoto, Miyuki Nakakuki, Nikolay Shcheynikov

Am J Physiol Gastrointest Liver Physiol· August 2015

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[Establishment of directed differentiation systems by manipulating transcription factors in pluripotent stem cells].
Tomohiko Akiyama, Yuhki Nakatake, Kohei Yamamizu, Atsumi Soma, Shigeru Ko, Minoru Ko

Nihon Rinsho· June 2015

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