Publications by authors named "Minoru Ko"

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Induced lung epithelial-like cells derived by direct reprogramming rescue influenza virus-induced lung injury in mice.
Tatsuya Kusumoto, Masaya Yotsukura, Takanori Asakura, Ho Namkoong, Takunori Ogawa, Junko Hamamoto, Minoru S H Ko, Koichi Fukunaga, Makoto Ishii

Biochem Biophys Res Commun· September 2025

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Direct reprogramming of mouse fibroblasts into self-renewable alveolar epithelial-like cells.
Atsuho Morita, Makoto Ishii, Takanori Asakura, Masaya Yotsukura, Ahmed E Hegab, Ho Namkoong, Junko Hamamoto, Minoru Ko, Koichi Fukunaga

NPJ Regen Med· June 2025

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Clinical Use of ZSCAN4 for Telomere Elongation in Hematopoietic Stem Cells.
Kasiani C Myers, Stella M Davies, Carolyn Lutzko, Robin Wahle, David D Grier, Minako Koga, Akihiro C Ko, Minoru S H Ko

NEJM Evid· March 2025

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ZSCAN4-binding motif-TGCACAC is conserved and enriched in CA/TG microsatellites in both mouse and human genomes.
Tomohiko Akiyama, Kei-Ichiro Ishiguro, Nana Chikazawa, Shigeru B H Ko, Masashi Yukawa, Minoru S H Ko

DNA Res· February 2024

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A Phase I/II Clinical Trial of Intradermal, Controllable Self-Replicating Ribonucleic Acid Vaccine EXG-5003 against SARS-CoV-2.
Takenao Koseki, Mayumi Teramachi, Minako Koga, Minoru S H Ko, Tomokazu Amano, Akihiro C Ko, Hisako Yoshida, Masashi Kondo

Vaccines (Basel)· November 2023

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SARS-CoV-2 infection establishes a stable and age-independent CD8 T cell response against a dominant nucleocapsid epitope using restricted T cell receptors.
Cecily Choy, Joseph Chen, Jiangyuan Li, D Travis Gallagher, Jian Lu, Minoru S H Ko

Nat Commun· October 2023

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Joint sequence & chromatin neural networks characterize the differential abilities of Forkhead transcription factors to engage inaccessible chromatin.
Sonny Arora, Jianyu Yang, Tomohiko Akiyama, Daniela Q James, Alexis Morrissey, Minoru S H Ko

bioRxiv· October 2023

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Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3.
Chie Kobori, Ryo Takagi, Ryo Yokomizo, Sakie Yoshihara, Mai Mori, Tomohiko Akiyama, Minoru S H Ko

Stem Cell Res Ther· September 2023

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Controllable self-replicating RNA vaccine delivered intradermally elicits predominantly cellular immunity.
Tomokazu Amano, Hong Yu, Misa Amano, Erica Leyder, Maria Badiola, Akihiro C Ko, Efrat Kochba, Minoru S H Ko

iScience· April 2023

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Controllable self-replicating RNA vaccine delivered intradermally elicits predominantly cellular immunity.
Tomokazu Amano, Hong Yu, Misa Amano, Erica Leyder, Maria Badiola, Akihiro C Ko, Efrat Kochba, Minoru S H Ko

bioRxiv· September 2022

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Purification of cardiomyocytes and neurons derived from human pluripotent stem cells by inhibition of fatty acid synthesis.
Sho Tanosaki, Tomohiko Akiyama, Sayaka Kanaami, Jun Fujita, Minoru S H Ko

STAR Protoc· June 2022

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Unbiased, comprehensive analysis of Japanese health checkup data reveals a protective effect of light to moderate alcohol consumption on lung function.
Kanako Makino, Ryoko Shimizu-Hirota, Norio Goda, Masahiro Hashimoto, Ichiro Kawada, Minoru Ko, Shigeru Ko

Sci Rep· August 2021

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Synthetic mRNA-based differentiation method enables early detection of Parkinson's phenotypes in neurons derived from Gaucher disease-induced pluripotent stem cells.
Tomohiko Akiyama, Saeko Sato, Shigeru B H Ko, Osamu Sano, Sho Sato, Minoru S H Ko

Stem Cells Transl Med· April 2021

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Fatty Acid Synthesis Is Indispensable for Survival of Human Pluripotent Stem Cells.
Sho Tanosaki, Shugo Tohyama, Jun Fujita, Shota Someya, Takako Hishiki, Tomohiko Akiyama, Minoru S H Ko, Makoto Suematsu

iScience· September 2020

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Generation and Profiling of 2,135 Human ESC Lines for the Systematic Analyses of Cell States Perturbed by Inducing Single Transcription Factors.
Yuhki Nakatake, Shigeru B H Ko, Alexei A Sharov, Shunichi Wakabayashi, Miyako Murakami, Miki Sakota, Saeko Sato, Noriko Ito, Misako Matsushita, Tomohiko Akiyama, Minoru S H Ko

Cell Rep· May 2020

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MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells.
Kei-Ichiro Ishiguro, Kumi Matsuura, Naoki Tani, Naoki Takeda, Shingo Usuki, Mariko Yamane, Michihiko Sugimoto, Sayoko Fujimura, Mihoko Hosokawa, Minoru S H Ko

Dev Cell· February 2020

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Induced Pluripotent Stem Cells Reprogrammed with Three Inhibitors Show Accelerated Differentiation Potentials with High Levels of 2-Cell Stage Marker Expression.
Koji Nishihara, Takahiro Shiga, Eri Nakamura, Tomohiko Akiyama, Takashi Sasaki, Minoru S H Ko

Stem Cell Reports· February 2019

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Induction of human pluripotent stem cells into kidney tissues by synthetic mRNAs encoding transcription factors.
Ken Hiratsuka, Toshiaki Monkawa, Tomohiko Akiyama, Yuhki Nakatake, Mayumi Oda, Saeko Sato, Shigeru B H Ko, Minoru S H Ko

Sci Rep· January 2019

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Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factors.
Hideomi Ida, Tomohiko Akiyama, Keiichiro Ishiguro, Sravan K Goparaju, Yuhki Nakatake, Saeko Sato, Yukihiro Yokoyama, Minoru S H Ko, Shigeru B H Ko

Stem Cell Res Ther· October 2018

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Efficient differentiation of human pluripotent stem cells into skeletal muscle cells by combining RNA-based MYOD1-expression and POU5F1-silencing.
Tomohiko Akiyama, Saeko Sato, Nana Chikazawa-Nohtomi, Atsumi Soma, Hiromi Kimura, Shigeru B H Ko, Minoru S H Ko

Sci Rep· January 2018

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SCODE: an efficient regulatory network inference algorithm from single-cell RNA-Seq during differentiation.
Hirotaka Matsumoto, Hisanori Kiryu, Chikara Furusawa, Minoru S H Ko, Shigeru B H Ko

Bioinformatics· August 2017

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Neural differentiation of human embryonic stem cells induced by the transgene-mediated overexpression of single transcription factors.
Misako Matsushita, Yuhki Nakatake, Itaru Arai, Keiji Ibata, Kazuhisa Kohda, Miyako Murakami, Miki Sakota, Shigeru B H Ko, Minoru S H Ko

Biochem Biophys Res Commun· August 2017

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Salt suppresses IFNγ inducible chemokines through the IFNγ-JAK1-STAT1 signaling pathway in proximal tubular cells.
Yohei Arai, Daiei Takahashi, Kenichi Asano, Masato Tanaka, Mayumi Oda, Shigeru B H Ko, Minoru S H Ko

Sci Rep· April 2017

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Epigenetic Manipulation Facilitates the Generation of Skeletal Muscle Cells from Pluripotent Stem Cells.
Tomohiko Akiyama, Shunichi Wakabayashi, Atsumi Soma, Saeko Sato, Yuhki Nakatake, Miyako Murakami, Miki Sakota, Shigeru B H Ko, Minoru S H Ko

Stem Cells Int· April 2017

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Identification of transcription factors that promote the differentiation of human pluripotent stem cells into lacrimal gland epithelium-like cells.
Masatoshi Hirayama, Shigeru B H Ko, Tetsuya Kawakita, Tomohiko Akiyama, Sravan K Goparaju, Miki Sakota, Minoru S H Ko

NPJ Aging Mech Dis· January 2017

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