Publications by authors named "Shinichi Kitada"

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Small molecule-induced mitochondrial disruption directs prostate cancer inhibition via UPR signaling.
Elizabeth Rico-Bautista, Wenhong Zhu, Shinichi Kitada, Suthakar Ganapathy, Eric Lau

Oncotarget· August 2013

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Targeted delivery of paclitaxel to EphA2-expressing cancer cells.
Si Wang, Roberta Noberini, John L Stebbins, Swadesh Das, Ziming Zhang, Shinichi Kitada

Clin Cancer Res· January 2013

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An optically pure apogossypolone derivative as potent pan-active inhibitor of anti-apoptotic bcl-2 family proteins.
Jun Wei, John L Stebbins, Shinichi Kitada, Rupesh Dash, Dayong Zhai

Front Oncol· August 2012

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Sabutoclax, a Mcl-1 antagonist, inhibits tumorigenesis in transgenic mouse and human xenograft models of prostate cancer.
Roger S Jackson, William Placzek, Ana Fernandez, Shabnam Ziaee, Chia-Yi Chu, Shinichi Kitada

Neoplasia· July 2012

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Efficient elimination of cancer cells by deoxyglucose-ABT-263/737 combination therapy.
Ryuji Yamaguchi, Edith Janssen, Guy Perkins, Mark Ellisman, Shinichi Kitada

PLoS One· March 2012

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Design and characterization of a potent and selective dual ATP- and substrate-competitive subnanomolar bidentate c-Jun N-terminal kinase (JNK) inhibitor.
John L Stebbins, Surya K De, Petra Pavlickova, Vida Chen, Thomas Machleidt, Shinichi Kitada

J Med Chem· September 2011

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Synthesis and biological evaluation of Apogossypolone derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.
Jun Wei, Shinichi Kitada, John L Stebbins, William Placzek, Dayong Zhai

J Med Chem· November 2010

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BI-97C1, an optically pure Apogossypol derivative as pan-active inhibitor of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.
Jun Wei, John L Stebbins, Shinichi Kitada, Rupesh Dash, William Placzek

J Med Chem· May 2010

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Chemical biology strategy reveals pathway-selective inhibitor of NF-kappaB activation induced by protein kinase C.
Ranxin Shi, Daniel Re, Eric Dudl, Michael Cuddy, Karl J Okolotowicz, Shinichi Kitada

ACS Chem Biol· March 2010

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Apogossypol derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.
Jun Wei, Shinichi Kitada, Michele F Rega, John L Stebbins, Dayong Zhai

J Med Chem· July 2009

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Apogossypol derivatives as antagonists of antiapoptotic Bcl-2 family proteins.
Jun Wei, Shinichi Kitada, Michele F Rega, Aras Emdadi, Hongbin Yuan

Mol Cancer Ther· April 2009

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Synthesis and evaluation of Apogossypol atropisomers as potential Bcl-xL antagonists.
Jun Wei, Michele F Rega, Shinichi Kitada, Hongbin Yuan, Dayong Zhai

Cancer Lett· January 2009

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A short Nur77-derived peptide converts Bcl-2 from a protector to a killer.
Siva Kumar Kolluri, Xiuwen Zhu, Xin Zhou, Bingzhen Lin, Ya Chen, Shinichi Kitada

Cancer Cell· October 2008

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Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins.
Dayong Zhai, Chaofang Jin, Chung-Wai Shiau, Shinichi Kitada, Arnold C Satterthwait

Mol Cancer Ther· June 2008

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Bcl-B expression in human epithelial and nonepithelial malignancies.
Maryla Krajewska, Shinichi Kitada, Jane N Winter, Daina Variakojis, Alan Lichtenstein

Clin Cancer Res· May 2008

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Bcl-2 antagonist apogossypol (NSC736630) displays single-agent activity in Bcl-2-transgenic mice and has superior efficacy with less toxicity compared with gossypol (NSC19048).
Shinichi Kitada, Christina L Kress, Maryla Krajewska, Lee Jia, Maurizio Pellecchia

Blood· March 2008

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Comparison of pharmacokinetic and metabolic profiling among gossypol, apogossypol and apogossypol hexaacetate.
Lee Jia, Lori C Coward, Corenna D Kerstner-Wood, Ronda L Cork, Gregory S Gorman, Shinichi Kitada

Cancer Chemother Pharmacol· January 2008

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Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997.
Michael R Grever, David M Lucas, Gordon W Dewald, Donna S Neuberg, John C Reed, Shinichi Kitada

J Clin Oncol· March 2007

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Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.
Marina Konopleva, Rooha Contractor, Twee Tsao, Ismael Samudio, Peter P Ruvolo, Shinichi Kitada

Cancer Cell· November 2006

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Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha.
Mitsufumi Nishio, Tomoyuki Endo, Nobuhiro Tsukada, Junko Ohata, Shinichi Kitada

Blood· August 2005

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours.
Tilman Oltersdorf, Steven W Elmore, Alexander R Shoemaker, Robert C Armstrong, David J Augeri, Shinichi Kitada

Nature· June 2005

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BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress.
Han-Jung Chae, Hyung-Ryong Kim, Chunyan Xu, Beatrice Bailly-Maitre, Maryla Krajewska, Shinichi Kitada

Mol Cell· August 2004

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MCL-1 promoter insertions dial-up aggressiveness of chronic leukemia.
Shinichi Kitada, John C Reed

J Natl Cancer Inst· May 2004

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Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-X(L).
Barbara Becattini, Shinichi Kitada, Marilisa Leone, Edward Monosov, Sharon Chandler

Chem Biol· March 2004

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Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity.
Aaron D Schimmer, Kate Welsh, Clemencia Pinilla, Zhiliang Wang, Maryla Krajewska, Shinichi Kitada

Cancer Cell· January 2004

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