Publications by authors named "Shinsuke Uda"

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Evaluation of the insulin-dependent and -independent hypoglycemic effects and understanding their breakdown in the progression of obesity using mice.
Fusako Kojima, So Morishita, Shinsuke Uda, Noriko Yutsudo, Yoshihiro Ogawa

PLoS One· December 2025

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Comparison of hepatic responses to glucose perturbation between healthy and obese mice based on the edge type of network structures.
Yuki Ito, Shinsuke Uda, Toshiya Kokaji, Akiyoshi Hirayama, Tomoyoshi Soga

Sci Rep· March 2023

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Four features of temporal patterns characterize similarity among individuals and molecules by glucose ingestion in humans.
Suguru Fujita, Yasuaki Karasawa, Masashi Fujii, Ken-Ichi Hironaka, Shinsuke Uda

NPJ Syst Biol Appl· February 2022

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An extensive and dynamic trans-omic network illustrating prominent regulatory mechanisms in response to insulin in the liver.
Fumiko Matsuzaki, Shinsuke Uda, Yukiyo Yamauchi, Masaki Matsumoto, Tomoyoshi Soga

Cell Rep· August 2021

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Trans-omic analysis reveals obesity-associated dysregulation of inter-organ metabolic cycles between the liver and skeletal muscle.
Riku Egami, Toshiya Kokaji, Atsushi Hatano, Katsuyuki Yugi, Miki Eto, Shinsuke Uda

iScience· March 2021

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Transomics analysis reveals allosteric and gene regulation axes for altered hepatic glucose-responsive metabolism in obesity.
Toshiya Kokaji, Atsushi Hatano, Yuki Ito, Katsuyuki Yugi, Miki Eto, Shinsuke Uda

Sci Signal· December 2020

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Single-Cell Information Analysis Reveals That Skeletal Muscles Incorporate Cell-to-Cell Variability as Information Not Noise.
Takumi Wada, Ken-Ichi Hironaka, Mitsutaka Wataya, Masashi Fujii, Miki Eto, Shinsuke Uda

Cell Rep· September 2020

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Logical design of oral glucose ingestion pattern minimizing blood glucose in humans.
Masashi Fujii, Yohei Murakami, Yasuaki Karasawa, Yohei Sumitomo, Suguru Fujita, Shinsuke Uda

NPJ Syst Biol Appl· April 2020

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Application of information theory in systems biology.
Shinsuke Uda

Biophys Rev· April 2020

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Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells.
Izumi Ohigashi, Yu Tanaka, Kenta Kondo, Sayumi Fujimori, Hiroyuki Kondo, Shinsuke Uda

Cell Rep· November 2019

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Reconstruction of global regulatory network from signaling to cellular functions using phosphoproteomic data.
Kentaro Kawata, Katsuyuki Yugi, Atsushi Hatano, Toshiya Kokaji, Yoko Tomizawa, Shinsuke Uda

Genes Cells· January 2019

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In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver.
Hiroyuki Kubota, Shinsuke Uda, Fumiko Matsuzaki, Yukiyo Yamauchi, Shinya Kuroda

Cell Syst· November 2018

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Trans-omic Analysis Reveals Selective Responses to Induced and Basal Insulin across Signaling, Transcriptional, and Metabolic Networks.
Kentaro Kawata, Atsushi Hatano, Katsuyuki Yugi, Hiroyuki Kubota, Takanori Sano, Shinsuke Uda

iScience· September 2018

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In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver.
Hiroyuki Kubota, Shinsuke Uda, Fumiko Matsuzaki, Yukiyo Yamauchi, Shinya Kuroda

Cell Syst· July 2018

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Increase in hepatic and decrease in peripheral insulin clearance characterize abnormal temporal patterns of serum insulin in diabetic subjects.
Kaoru Ohashi, Masashi Fujii, Shinsuke Uda, Hiroyuki Kubota, Hisako Komada

NPJ Syst Biol Appl· March 2018

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System identification of signaling dependent gene expression with different time-scale data.
Takaho Tsuchiya, Masashi Fujii, Naoki Matsuda, Katsuyuki Kunida, Shinsuke Uda

PLoS Comput Biol· December 2017

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Laguerre Filter Analysis with Partial Least Square Regression Reveals a Priming Effect of ERK and CREB on c-FOS Induction.
Takamasa Kudo, Shinsuke Uda, Takaho Tsuchiya, Takumi Wada, Yasuaki Karasawa

PLoS One· July 2017

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Selective control of up-regulated and down-regulated genes by temporal patterns and doses of insulin.
Takanori Sano, Kentaro Kawata, Satoshi Ohno, Katsuyuki Yugi, Hiroaki Kakuda, Shinsuke Uda

Sci Signal· November 2016

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Glucose Homeostatic Law: Insulin Clearance Predicts the Progression of Glucose Intolerance in Humans.
Kaoru Ohashi, Hisako Komada, Shinsuke Uda, Hiroyuki Kubota, Toshinao Iwaki

PLoS One· June 2016

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Analysis of cellular signal transduction from an information theoretic approach.
Shinsuke Uda, Shinya Kuroda

Semin Cell Dev Biol· March 2016

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Reconstruction of insulin signal flow from phosphoproteome and metabolome data.
Katsuyuki Yugi, Hiroyuki Kubota, Yu Toyoshima, Rei Noguchi, Kentaro Kawata, Shinsuke Uda

Cell Rep· August 2014

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The extraction of simple relationships in growth factor-specific multiple-input and multiple-output systems in cell-fate decisions by backward elimination PLS regression.
Yuki Akimoto, Katsuyuki Yugi, Shinsuke Uda, Takamasa Kudo, Yasunori Komori

PLoS One· June 2014

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Temporal decoding of MAP kinase and CREB phosphorylation by selective immediate early gene expression.
Takeshi H Saito, Shinsuke Uda, Takaho Tsuchiya, Yu-ichi Ozaki, Shinya Kuroda

PLoS One· August 2013

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Robustness and compensation of information transmission of signaling pathways.
Shinsuke Uda, Takeshi H Saito, Takamasa Kudo, Toshiya Kokaji, Takaho Tsuchiya

Science· August 2013

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Temporal coding of insulin action through multiplexing of the AKT pathway.
Hiroyuki Kubota, Rei Noguchi, Yu Toyoshima, Yu-Ichi Ozaki, Shinsuke Uda

Mol Cell· June 2012

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