Publications by authors named "Silva Fredduzzi"

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Fused tricyclic mGluR1 antagonists for the treatment of neuropathic pain.
Chad E Bennett, Duane A Burnett, William J Greenlee, Chad E Knutson, Peter Korakas, Silva Fredduzzi

Bioorg Med Chem Lett· February 2012

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Characterization of the potent and highly selective A2A receptor antagonists preladenant and SCH 412348 [7-[2-[4-2,4-difluorophenyl]-1-piperazinyl]ethyl]-2-(2-furanyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine] in rodent models of movement disorders and depression.
Robert A Hodgson, Rosalia Bertorelli, Geoffrey B Varty, Jean E Lachowicz, Angelo Forlani, Silva Fredduzzi

J Pharmacol Exp Ther· July 2009

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Potent and selective adenosine A2A receptor antagonists: 1,2,4-Triazolo[1,5-c]pyrimidines.
Bernard R Neustadt, Hong Liu, Jinsong Hao, William J Greenlee, Andrew W Stamford, Silva Fredduzzi

Bioorg Med Chem Lett· February 2009

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Discovery of orally efficacious tetracyclic metabotropic glutamate receptor 1 (mGluR1) antagonists for the treatment of chronic pain.
Wen-Lian Wu, Duane A Burnett, Martin Domalski, William J Greenlee, Cheng Li, Silva Fredduzzi

J Med Chem· November 2007

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The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles.
Geoffrey B Varty, Mariagrazia Grilli, Angelo Forlani, Silva Fredduzzi, Michael E Grzelak

Psychopharmacology (Berl)· April 2005

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Endogenous and exogenous melanocortin antagonists induce anti-allodynic effects in a model of rat neuropathic pain.
Rosalia Bertorelli, Silva Fredduzzi, Glauco Tarozzo, Marilena Campanella, Robert Grundy

Behav Brain Res· February 2005

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Adenosine A2A receptors in neuroadaptation to repeated dopaminergic stimulation: implications for the treatment of dyskinesias in Parkinson's disease.
Jiang-Fan Chen, Silva Fredduzzi, Elena Bastia, Liqun Yu, Rosario Moratalla

Neurology· December 2003

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Gene expression profiling of melanocortin system in neuropathic rats supports a role in nociception.
Massimiliano Beltramo, Marilena Campanella, Glauco Tarozzo, Silva Fredduzzi, Laura Corradini

Brain Res Mol Brain Res· October 2003

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Persistent behavioral sensitization to chronic L-DOPA requires A2A adenosine receptors.
Silva Fredduzzi, Rosario Moratalla, Angela Monopoli, Beatriz Cuellar, Kui Xu

J Neurosci· February 2002

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