Publications by authors named "Simon Hubbard"

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Translation is an emerging constraint on protein homeostasis in ageing.
Jack Llewellyn, Simon J Hubbard, Joe Swift

Trends Cell Biol· August 2024

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Isoform-specific sequestration of protein kinase A fine-tunes intracellular signaling during heat stress.
Declan R Creamer, Robert J Beynon, Simon J Hubbard, Mark P Ashe, Chris M Grant

Cell Rep· June 2024

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Proteogenomic Gene Structure Validation in the Pineapple Genome.
Norazrin Ariffin, David Wells Newman, Michael G Nelson, Ronan O'cualain, Simon J Hubbard

J Proteome Res· May 2024

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Translation factor and RNA binding protein mRNA interactomes support broader RNA regulons for posttranscriptional control.
Christopher J Kershaw, Michael G Nelson, Lydia M Castelli, Martin D Jennings, Jennifer Lui, Simon J Hubbard

J Biol Chem· October 2023

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Paralogous translation factors target distinct mRNAs to differentially regulate tolerance to oxidative stress in yeast.
Joanne Cunningham, Aristeidis P Sfakianos, Paraskevi Kritsiligkou, Christopher J Kershaw, Alan J Whitmarsh, Simon J Hubbard

Nucleic Acids Res· September 2023

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Loss of regulation of protein synthesis and turnover underpins an attenuated stress response in senescent human mesenchymal stem cells.
Jack Llewellyn, Venkatesh Mallikarjun, Ellen Appleton, Maria Osipova, Hamish T J Gilbert, Simon J Hubbard

Proc Natl Acad Sci U S A· April 2023

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AlacatDesigner─Computational Design of Peptide Concatamers for Protein Quantitation.
Martin Rusilowicz, David W Newman, Declan R Creamer, James Johnson, Kareena Adair, Simon J Hubbard

J Proteome Res· February 2023

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Uncertainty-Aware Protein-Level Quantification and Differential Expression Analysis of Proteomics Data with seaMass.
Alexander M Phillips, Richard D Unwin, Simon J Hubbard, Andrew W Dowsey

Methods Mol Biol· November 2022

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Understanding the Role of Yeast Yme1 in Mitochondrial Function Using Biochemical and Proteomics Analyses.
Kwan Ting Kan, Michael G Nelson, Chris M Grant, Simon J Hubbard, Hui Lu

Int J Mol Sci· November 2022

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Yeast Protein Kinase A Isoforms: A Means of Encoding Specificity in the Response to Diverse Stress Conditions?
Declan R Creamer, Simon J Hubbard, Mark P Ashe, Chris M Grant

Biomolecules· July 2022

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Implementing the reuse of public DIA proteomics datasets: from the PRIDE database to Expression Atlas.
Mathias Walzer, David García-Seisdedos, Ananth Prakash, Paul Brack, Peter Crowther, Simon J Hubbard

Sci Data· June 2022

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Cytosolic aspartate aminotransferase moonlights as a ribosome-binding modulator of Gcn2 activity during oxidative stress.
Robert A Crawford, Mark P Ashe, Simon J Hubbard, Graham D Pavitt

Elife· May 2022

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MRSD: A quantitative approach for assessing suitability of RNA-seq in the investigation of mis-splicing in Mendelian disease.
Charlie F Rowlands, Algy Taylor, Gillian Rice, Nicola Whiffin, Hildegard Nikki Hall, Simon Hubbard

Am J Hum Genet· February 2022

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Whole-cell modeling in yeast predicts compartment-specific proteome constraints that drive metabolic strategies.
Ibrahim E Elsemman, Angelica Rodriguez Prado, Pranas Grigaitis, Manuel Garcia Albornoz, Victoria Harman, Simon Hubbard

Nat Commun· February 2022

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Integrated multi-omics reveals common properties underlying stress granule and P-body formation.
Christopher J Kershaw, Michael G Nelson, Jennifer Lui, Christian P Bates, Martin D Jennings, Simon J Hubbard

RNA Biol· November 2021

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Core Fermentation (CoFe) granules focus coordinated glycolytic mRNA localization and translation to fuel glucose fermentation.
Fabian Morales-Polanco, Christian Bates, Jennifer Lui, Joseph Casson, Clara A Solari, Simon Hubbard

iScience· February 2021

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Characterisation of protein isoforms encoded by the Drosophila Glycogen Synthase Kinase 3 gene shaggy.
Dagmara Korona, Daniel Nightingale, Bertrand Fabre, Michael Nelson, Bettina Fischer, Simon Hubbard

PLoS One· October 2020

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Disease modeling of core pre-mRNA splicing factor haploinsufficiency.
Katherine A Wood, Charlie F Rowlands, Wasay Mohiuddin Shaikh Qureshi, Huw B Thomas, Weronika A Buczek, Simon J Hubbard

Hum Mol Genet· November 2019

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Glycolytic flux in is dependent on RNA polymerase III and its negative regulator Maf1.
Roza Szatkowska, Manuel Garcia-Albornoz, Katarzyna Roszkowska, Stephen W Holman, Emil Furmanek, Simon J Hubbard

Biochem J· April 2019

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Ribosomal flavours: an acquired taste for specific mRNAs?
Christian Bates, Simon J Hubbard, Mark P Ashe

Biochem Soc Trans· December 2018

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Archetypal transcriptional blocks underpin yeast gene regulation in response to changes in growth conditions.
David Talavera, Christopher J Kershaw, Joseph L Costello, Lydia M Castelli, William Rowe, Simon J Hubbard

Sci Rep· May 2018

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A quantitative and temporal map of proteostasis during heat shock in Saccharomyces cerevisiae.
Andrew F Jarnuczak, Manuel Garcia Albornoz, Claire E Eyers, Christopher M Grant, Simon J Hubbard

Mol Omics· February 2018

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Dynamic changes in eIF4F-mRNA interactions revealed by global analyses of environmental stress responses.
Joseph L Costello, Christopher J Kershaw, Lydia M Castelli, David Talavera, William Rowe, Simon J Hubbard

Genome Biol· October 2017

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Dynamic Acclimation to High Light in Involves Widespread Reengineering of the Leaf Proteome.
Matthew A E Miller, Ronan O'Cualain, Julian Selley, David Knight, Mohd F Karim, Simon J Hubbard

Front Plant Sci· July 2017

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Analysis of Intrinsic Peptide Detectability via Integrated Label-Free and SRM-Based Absolute Quantitative Proteomics.
Andrew F Jarnuczak, Dave C H Lee, Craig Lawless, Stephen W Holman, Claire E Eyers, Simon J Hubbard

J Proteome Res· September 2016

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