Publications by authors named "Stan Pasyk"

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Synergy of cAMP and calcium signaling pathways in CFTR regulation.
Zoltan Bozoky, Saumel Ahmadi, Tal Milman, Tae Hun Kim, Kai Du, Stan Pasyk

Proc Natl Acad Sci U S A· March 2017

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Sphingosine-1-Phosphate Is a Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity.
Firhan A Malik, Anja Meissner, Illya Semenkov, Steven Molinski, Stan Pasyk

PLoS One· April 2016

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The major cystic fibrosis causing mutation exhibits defective propensity for phosphorylation.
Stan Pasyk, Steven Molinski, Saumel Ahmadi, Mohabir Ramjeesingh, Ling-Jun Huan

Proteomics· January 2015

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VX-809 and related corrector compounds exhibit secondary activity stabilizing active F508del-CFTR after its partial rescue to the cell surface.
Paul D W Eckford, Mohabir Ramjeesingh, Steven Molinski, Stan Pasyk, Johanna F Dekkers

Chem Biol· May 2014

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Functional Rescue of F508del-CFTR Using Small Molecule Correctors.
Steven Molinski, Paul D W Eckford, Stan Pasyk, Saumel Ahmadi, Stephanie Chin

Front Pharmacol· October 2012

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Identification and validation of hits from high throughput screens for CFTR modulators.
Stan Pasyk, Steven Molinski, Wilson Yu, Paul D W Eckford, Christine E Bear

Curr Pharm Des· June 2012

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A small-molecule modulator interacts directly with deltaPhe508-CFTR to modify its ATPase activity and conformational stability.
Leigh Wellhauser, Patrick Kim Chiaw, Stan Pasyk, Canhui Li, Mohabir Ramjeesingh

Mol Pharmacol· June 2009

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Direct interaction of a small-molecule modulator with G551D-CFTR, a cystic fibrosis-causing mutation associated with severe disease.
Stan Pasyk, Canhui Li, Mohabir Ramjeesingh, Christine E Bear

Biochem J· February 2009

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Molecular basis for the ATPase activity of CFTR.
Joanne C Cheung, Patrick Kim Chiaw, Stan Pasyk, Christine E Bear

Arch Biochem Biophys· August 2008

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