Publications by authors named "Stepan Denisov"

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Chemokine-Binding All-D-CLIPS Peptides Identified Using Mirror-Image Phage Display.
Stepan S Denisov, Emilia L Bialek, Fabio Beretta, Gintare Smagurauskaite, Hans Ippel

ACS Chem Biol· November 2025

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Unravelling the Functional Diversity of Type III Polyketide Synthases in Fungi.
Nika Sokolova, Stepan S Denisov, Thomas Hackl, Kristina Haslinger

Angew Chem Int Ed Engl· October 2025

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Evasin and TSLPI Tick Salivary Antigen Subunit Vaccine Nanoparticles Induce Humoral and Cellular Immunity.
Jaeyoung Park, Thomas Pho, Stepan S Denisov, Ingrid Dijkgraaf, Julie A Champion

ACS Nanosci Au· October 2025

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Deciphering the Foundations of Mitochondrial Mutational Spectra: Replication-Driven and Damage-Induced Signatures Across Chordate Classes.
Dmitrii Iliushchenko, Bogdan Efimenko, Alina G Mikhailova, Victor Shamanskiy, Murat K Saparbaev, Stepan Denisov

Mol Biol Evol· February 2025

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High-throughput method characterizes hundreds of previously unknown antibiotic resistance mutations.
Matthew J Jago, Jake K Soley, Stepan Denisov, Calum J Walsh, Danna R Gifford

Nat Commun· January 2025

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Discovery and pharmacophoric characterization of chemokine network inhibitors using phage-display, saturation mutagenesis and computational modelling.
Serena Vales, Jhanna Kryukova, Soumyanetra Chandra, Gintare Smagurauskaite, Megan Payne, Stepan Denisov

Nat Commun· September 2023

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A mitochondria-specific mutational signature of aging: increased rate of A > G substitutions on the heavy strand.
Alina G Mikhailova, Alina A Mikhailova, Kristina Ushakova, Evgeny O Tretiakov, Dmitrii Iliushchenko, Stepan Denisov

Nucleic Acids Res· October 2022

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Vaccination with a bacterial peptide conjugated to SARS-CoV-2 receptor-binding domain accelerates immunity and protects against COVID-19.
Athanasios Blanas, Haiko Karsjens, Aafke de Ligt, Elisabeth J M Huijbers, Karlijn van Loon, Stepan S Denisov

iScience· August 2022

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Extracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapy.
Judy R van Beijnum, Elisabeth J M Huijbers, Karlijn van Loon, Athanasios Blanas, Parvin Akbari, Stepan S Denisov

Nat Commun· May 2022

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CXCL17: The Black Sheep in the Chemokine Flock.
Stepan S Denisov

Front Immunol· December 2021

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Immunomodulatory Proteins in Tick Saliva From a Structural Perspective.
Stepan S Denisov, Ingrid Dijkgraaf

Front Cell Infect Microbiol· November 2021

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Molecular basis of anticoagulant and anticomplement activity of the tick salivary protein Salp14 and its homologs.
Stepan S Denisov, Johannes H Ippel, Elisabetta Castoldi, Ben J Mans, Tilman M Hackeng

J Biol Chem· July 2021

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An extended catalogue of tandem alternative splice sites in human tissue transcriptomes.
Aleksei Mironov, Stepan Denisov, Alexander Gress, Olga V Kalinina, Dmitri D Pervouchine

PLoS Comput Biol· April 2021

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Conserved long-range base pairings are associated with pre-mRNA processing of human genes.
Svetlana Kalmykova, Marina Kalinina, Stepan Denisov, Alexey Mironov, Dmitry Skvortsov

Nat Commun· April 2021

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Structural characterization of anti-CCL5 activity of the tick salivary protein evasin-4.
Stepan S Denisov, Mercedes Ramírez-Escudero, Alexandra C A Heinzmann, Johannes H Ippel, Philip E Dawson

J Biol Chem· October 2020

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Tick Saliva Protein Evasin-3 Allows for Visualization of Inflammation in Arteries through Interactions with CXC-Type Chemokines Deposited on Activated Endothelium.
Stepan S Denisov, Alexandra C A Heinzmann, Tanja Vajen, Mark H M Vries, Remco T A Megens

Bioconjug Chem· March 2020

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Fluorescein Derivatives as Antibacterial Agents Acting via Membrane Depolarization.
Pavel A Nazarov, Roman S Kirsanov, Stepan S Denisov, Ljudmila S Khailova, Marina V Karakozova

Biomolecules· February 2020

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Tick saliva protein Evasin-3 modulates chemotaxis by disrupting CXCL8 interactions with glycosaminoglycans and CXCR2.
Stepan S Denisov, Johannes H Ippel, Alexandra C A Heinzmann, Rory R Koenen, Almudena Ortega-Gomez

J Biol Chem· August 2019

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SecScan: a general approach for mapping disulfide bonds in synthetic and recombinant peptides and proteins.
Stepan S Denisov, Johannes H Ippel, Ben J Mans, Ingrid Dijkgraaf, Tilman M Hackeng

Chem Commun (Camb)· January 2019

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Alkyl-substituted phenylamino derivatives of 7-nitrobenz-2-oxa-1,3-diazole as uncouplers of oxidative phosphorylation and antibacterial agents: involvement of membrane proteins in the uncoupling action.
Yuri N Antonenko, Stepan S Denisov, Ljudmila S Khailova, Pavel A Nazarov, Tatyana Rokitskaya

Biochim Biophys Acta Biomembr· March 2017

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A long-linker conjugate of fluorescein and triphenylphosphonium as mitochondria-targeted uncoupler and fluorescent neuro- and nephroprotector.
Yuri N Antonenko, Stepan S Denisov, Denis N Silachev, Ljudmila S Khailova, Stanislovas S Jankauskas

Biochim Biophys Acta· November 2016

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Correlated Evolution of Nucleotide Positions within Splice Sites in Mammals.
Stepan Denisov, Georgii Bazykin, Alexander Favorov, Andrey Mironov, Mikhail Gelfand

PLoS One· June 2016

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A mitochondria-targeted protonophoric uncoupler derived from fluorescein.
Stepan S Denisov, Elena A Kotova, Egor Y Plotnikov, Artur A Tikhonov, Dmitry B Zorov

Chem Commun (Camb)· December 2014

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Tuning the hydrophobicity overcomes unfavorable deprotonation making octylamino-substituted 7-nitrobenz-2-oxa-1,3-diazole (n-octylamino-NBD) a protonophore and uncoupler of oxidative phosphorylation in mitochondria.
Stepan S Denisov, Elena A Kotova, Ljudmila S Khailova, Galina A Korshunova, Yuri N Antonenko

Bioelectrochemistry· August 2014

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Weak negative and positive selection and the drift load at splice sites.
Stepan V Denisov, Georgii A Bazykin, Roman Sutormin, Alexander V Favorov, Andrey A Mironov

Genome Biol Evol· May 2014

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