Publications by authors named "Stephen Alves"

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Clonal relationships between Tph and Tfh cells in patients with SLE and in murine lupus.
Takanori Sasaki, John Sowerby, Yinan Xiao, Runci Wang, Snigdha Samarpita, Stephen E Alves

Res Sq· September 2025

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Clonal relationships between Tph and Tfh cells in patients with SLE and in murine lupus.
Takanori Sasaki, John Sowerby, Yinan Xiao, Runci Wang, Snigdha Samarpita, Stephen E Alves

bioRxiv· August 2025

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Publisher Correction: Interferon subverts an AHR-JUN axis to promote CXCL13 T cells in lupus.
Calvin Law, Vanessa Sue Wacleche, Ye Cao, Arundhati Pillai, John Sowerby, Stephen E Alves

Nature· August 2024

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Interferon subverts an AHR-JUN axis to promote CXCL13 T cells in lupus.
Calvin Law, Vanessa Sue Wacleche, Ye Cao, Arundhati Pillai, John Sowerby, Stephen E Alves

Nature· July 2024

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Establishment of a 96-well transwell system using primary human gut organoids to capture multiple quantitative pathway readouts.
Charles W Wright, Naomi Li, Lynsey Shaffer, Armetta Hill, Nicolas Boyer, Stephen E Alves

Sci Rep· September 2023

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Longitudinal Immune Cell Profiling in Patients With Early Systemic Lupus Erythematosus.
Takanori Sasaki, Sabrina Bracero, Joshua Keegan, Lin Chen, Ye Cao, Stephen E Alves

Arthritis Rheumatol· November 2022

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Projected Dose Optimization of Amino- and Hydroxypyrrolidine Purine PI3Kδ Immunomodulators.
Joey L Methot, Hua Zhou, Meredeth A McGowan, Neville John Anthony, Matthew Christopher, Stephen Alves

J Med Chem· April 2021

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A Microengineered Airway Lung Chip Models Key Features of Viral-induced Exacerbation of Asthma.
Janna C Nawroth, Carolina Lucchesi, Deion Cheng, Abhishek Shukla, Justin Ngyuen, Stephen Alves

Am J Respir Cell Mol Biol· November 2020

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PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21.
Alexandra V Bocharnikov, Joshua Keegan, Vanessa S Wacleche, Ye Cao, Chamith Y Fonseka, Stephen E Alves

JCI Insight· October 2019

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Characterizing Pharmacokinetic-Pharmacodynamic Relationships and Efficacy of PI3K Inhibitors in Respiratory Models of TH2 and TH1 Inflammation.
Robbie L McLeod, Malgorzata A Gil, Dapeng Chen, Antonio Cabal, Jason Katz, Stephen Alves

J Pharmacol Exp Ther· May 2019

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The NLRP3 inflammasome mediates DSS-induced intestinal inflammation in Nod2 knockout mice.
Benjamin Umiker, Hyun-Hee Lee, Julia Cope, Nadim J Ajami, Jean-Philippe Laine, Stephen E Alves

Innate Immun· February 2019

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A human tissue-based functional assay platform to evaluate the immune function impact of small molecule inhibitors that target the immune system.
Cristina St Pierre, Jane Guo, John D Shin, Laura W Engstrom, Hyun-Hee Lee, Stephen E Alves

PLoS One· September 2017

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Inhibition of spleen tyrosine kinase attenuates IgE-mediated airway contraction and mediator release in human precision cut lung slices.
Cynthia J Koziol-White, Yanlin Jia, Gretchen A Baltus, Philip R Cooper, Dennis M Zaller, Stephen E Alves

Br J Pharmacol· November 2016

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A novel selective androgen receptor modulator (SARM) MK-4541 exerts anti-androgenic activity in the prostate cancer xenograft R-3327G and anabolic activity on skeletal muscle mass & function in castrated mice.
Michael J Chisamore, Michael A Gentile, Gregory Michael Dillon, Matthew Baran, Carlo Gambone, Stephen E Alves

J Steroid Biochem Mol Biol· October 2016

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Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro.
Kambez H Benam, Remi Villenave, Carolina Lucchesi, Antonio Varone, Cedric Hubeau, Stephen E Alves

Nat Methods· February 2016

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Phenotypic responses of differentiated asthmatic human airway epithelial cultures to rhinovirus.
Jianwu Bai, Steven L Smock, George R Jackson, Kenzie D MacIsaac, Yongsheng Huang, Stephen E Alves

PLoS One· November 2015

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Identification of an anabolic selective androgen receptor modulator that actively induces death of androgen-independent prostate cancer cells.
Azriel Schmidt, Robert S Meissner, Michael A Gentile, Michael J Chisamore, Evan E Opas, Stephen E Alves

J Steroid Biochem Mol Biol· September 2014

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Increased muscle force production and bone mineral density in ActRIIB-Fc-treated mature rodents.
Chi-Sung Chiu, Norbert Peekhaus, Hans Weber, Sharon Adamski, Edward M Murray, Stephen E Alves

J Gerontol A Biol Sci Med Sci· October 2013

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Identification and characterization of lipopolysaccharide binding protein (LBP) as an estrogen receptor α specific serum biomarker.
Michael J Chisamore, Kwok-Lam Karen Hong, Chun Cheng, Stephen E Alves, Susan P Rohrer

Biomarkers· March 2012

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Non-invasive muscle contraction assay to study rodent models of sarcopenia.
Chi-Sung Chiu, Hans Weber, Sharon Adamski, Albert Rauch, Michael A Gentile, Stephen E Alves

BMC Musculoskelet Disord· October 2011

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Comparative analysis of the effects of antimuscarinic agents on bladder functions in both nonhuman primates and rodents.
Hiroshi Nagabukuro, Katherine L Villa, L Alexandra Wickham, Alison A Kulick, Loise Gichuru, Stephen E Alves

J Pharmacol Exp Ther· July 2011

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Estrogen receptor (ER) subtype agonists alter monoamine levels in the female rat brain.
Laura S Lubbers, Peter T Zafian, Claris Gautreaux, Marisa Gordon, Stephen E Alves

J Steroid Biochem Mol Biol· November 2010

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Estradiol and ERβ agonists enhance recognition memory, and DPN, an ERβ agonist, alters brain monoamines.
Luis F Jacome, Claris Gautreaux, Tomoko Inagaki, Govini Mohan, Stephen Alves

Neurobiol Learn Mem· November 2010

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Nuclear and extranuclear estrogen binding sites in the rat forebrain and autonomic medullary areas.
Teresa A Milner, Laura S Lubbers, Stephen E Alves, Bruce S McEwen

Endocrinology· July 2008

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Evidence that estrogen directly and indirectly modulates C1 adrenergic bulbospinal neurons in the rostral ventrolateral medulla.
Gang Wang, Carrie T Drake, Mariya Rozenblit, Ping Zhou, Stephen E Alves

Brain Res· June 2006

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