Publications by authors named "Stephen Helfand"

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The Fourth Annual Symposium of the Midwest Aging Consortium.
Jinoh Kim, Rochelle Buffenstein, Anne M Bronikowski, Natalia-Del Pilar Vanegas, Lorena Rosas, Stephen L Helfand

J Gerontol A Biol Sci Med Sci· November 2024

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A specialized metabolic pathway partitions citrate in hydroxyapatite to impact mineralization of bones and teeth.
Naomi Dirckx, Qian Zhang, Emily Y Chu, Robert J Tower, Zhu Li, Stephen L Helfand

Proc Natl Acad Sci U S A· November 2022

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Sirt6 regulates lifespan in .
Jackson R Taylor, Jason G Wood, Evan Mizerak, Samuel Hinthorn, Julianna Liu, Stephen L Helfand

Proc Natl Acad Sci U S A· February 2022

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Evidence that overnight fasting could extend healthy lifespan.
Stephen L Helfand, Rafael de Cabo

Nature· October 2021

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The role of retrotransposable elements in ageing and age-associated diseases.
Vera Gorbunova, Andrei Seluanov, Paolo Mita, Wilson McKerrow, David Fenyö, Stephen L Helfand

Nature· August 2021

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The longevity gene mIndy (I'm Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms.
Diana M Willmes, Martin Daniels, Anica Kurzbach, Stefanie Lieske, Nicole Bechmann, Stephen L Helfand

JCI Insight· January 2021

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Author Correction: L1 drives IFN in senescent cells and promotes age-associated inflammation.
Marco De Cecco, Takahiro Ito, Anna P Petrashen, Amy E Elias, Nicholas J Skvir, Stephen L Helfand

Nature· August 2019

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LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation.
Matthew Simon, Michael Van Meter, Julia Ablaeva, Zhonghe Ke, Raul S Gonzalez, Stephen L Helfand

Cell Metab· April 2019

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L1 drives IFN in senescent cells and promotes age-associated inflammation.
Marco De Cecco, Takahiro Ito, Anna P Petrashen, Amy E Elias, Nicholas J Skvir, Stephen L Helfand

Nature· February 2019

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The longevity gene INDY (I'm Not Dead Yet) in metabolic control: Potential as pharmacological target.
Diana M Willmes, Anica Kurzbach, Christine Henke, Tina Schumann, Grit Zahn, Stephen L Helfand

Pharmacol Ther· May 2018

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Sirt4 is a mitochondrial regulator of metabolism and lifespan in .
Jason G Wood, Bjoern Schwer, Priyan C Wickremesinghe, Davis A Hartnett, Lucas Burhenn, Stephen L Helfand

Proc Natl Acad Sci U S A· February 2018

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The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism.
Christian von Loeffelholz, Stefanie Lieske, Frank Neuschäfer-Rube, Diana M Willmes, Nathanael Raschzok, Stephen L Helfand

Hepatology· August 2017

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A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan.
Brian C Jones, Jason G Wood, Chengyi Chang, Austin D Tam, Michael J Franklin, Stephen L Helfand

Nat Commun· December 2016

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Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila.
Jason G Wood, Brian C Jones, Nan Jiang, Chengyi Chang, Suzanne Hosier, Stephen L Helfand

Proc Natl Acad Sci U S A· October 2016

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The longevity transporter mIndy (Slc13a5) as a target for treating hepatic steatosis and insulin resistance.
Diana M Willmes, Stephen L Helfand, Andreas L Birkenfeld

Aging (Albany NY)· February 2016

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Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span.
Mintie Pu, Zhuoyu Ni, Minghui Wang, Xiujuan Wang, Jason G Wood, Stephen L Helfand

Genes Dev· April 2015

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Human Genomics. Sleeping dogs of the genome.
Vera Gorbunova, Jef D Boeke, Stephen L Helfand, John M Sedivy

Science· December 2014

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Transcriptional response to dietary restriction in Drosophila melanogaster.
Feifei Ding, M Pilar Gil, Michael Franklin, Jonathan Ferreira, Marc Tatar, Stephen L Helfand

J Insect Physiol· October 2014

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RNA editing regulates transposon-mediated heterochromatic gene silencing.
Yiannis A Savva, James E C Jepson, Yao-Jen Chang, Rachel Whitaker, Brian C Jones, Stephen L Helfand

Nat Commun· June 2014

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Dietary switch reveals fast coordinated gene expression changes in Drosophila melanogaster.
Rachel Whitaker, M Pilar Gil, Feifei Ding, Marc Tatar, Stephen L Helfand

Aging (Albany NY)· May 2014

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Genetic and biochemical tools for investigating sirtuin function in Drosophila melanogaster.
Jason G Wood, Rachel Whitaker, Stephen L Helfand

Methods Mol Biol· April 2014

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Indy gene variation in natural populations confers fitness advantage and life span extension through transposon insertion.
Chen-Tseh Zhu, Chengyi Chang, Robert A Reenan, Stephen L Helfand

Aging (Albany NY)· January 2014

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Chromatin structure and transposable elements in organismal aging.
Jason G Wood, Stephen L Helfand

Front Genet· December 2013

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Dietary and genetic effects on age-related loss of gene silencing reveal epigenetic plasticity of chromatin repression during aging.
Nan Jiang, Guyu Du, Ethan Tobias, Jason G Wood, Rachel Whitaker, Stephen L Helfand

Aging (Albany NY)· November 2013

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Increased expression of Drosophila Sir2 extends life span in a dose-dependent manner.
Rachel Whitaker, Shakeela Faulkner, Reika Miyokawa, Lucas Burhenn, Mark Henriksen, Stephen L Helfand

Aging (Albany NY)· September 2013

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