Publications by authors named "Steve Gygi"

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GCN1 couples GCN2 to ribosomal state to initiate amino acid response pathway signaling.
Changqian Zhou, Miao Zhang, Jason Murray, Joao Paulo, Steve Gygi

Science· October 2025

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Heterogeneity of Extracellular Vesicles and Non-Vesicular Nanoparticles in Glioblastoma.
Tuoye Xu, Joao A Paulo, Piyan Zhang, Xinyue Liu, Alya Nguyen, Steve P Gygi

J Extracell Vesicles· October 2025

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ALS-related p97 R155H mutation disrupts lysophagy in iPSC-derived motor neurons.
Jacob A Klickstein, Michelle A Johnson, Pantelis Antonoudiou, Jamie Maguire, Joao A Paulo, Steve P Gygi

Stem Cell Reports· May 2025

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Selective deficiency of mitochondrial respiratory complex I subunits Ndufs4/6 causes tumor immunogenicity.
Jiaxin Liang, Tevis Vitale, Xixi Zhang, Thomas D Jackson, Deyang Yu, Steve P Gygi

Nat Cancer· February 2025

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USP14 inhibition enhances Parkin-independent mitophagy in iNeurons.
Greta Bernardo, Miguel A Prado, Anna Roshani Dashtmian, Mariavittoria Favaro, Sofia Mauri, Steve P Gygi

Pharmacol Res· December 2024

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ALS-related p97 R155H mutation disrupts lysophagy in iPSC-derived motor neurons.
Jacob A Klickstein, Michelle A Johnson, Pantelis Antonoudiou, Jamie Maguire, Joao A Paulo, Steve P Gygi

Stem Cell Reports· March 2024

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UBXN1 maintains ER proteostasis and represses UPR activation by modulating translation.
Brittany A Ahlstedt, Rakesh Ganji, Sirisha Mukkavalli, Joao A Paulo, Steve P Gygi

EMBO Rep· February 2024

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Selective Mitochondrial Respiratory Complex I Subunit Deficiency Causes Tumor Immunogenicity.
Jiaxin Liang, Tevis Vitale, Xixi Zhang, Thomas D Jackson, Deyang Yu, Steve P Gygi

bioRxiv· October 2023

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Epigenetic suppression of PGC1α (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas.
Jiaxin Liang, Deyang Yu, Chi Luo, Christopher Bennett, Mark Jedrychowski, Steve P Gygi

Nat Commun· June 2023

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The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition.
Rakesh Ganji, Joao A Paulo, Yuecheng Xi, Ian Kline, Jiang Zhu, Steve P Gygi

Nat Commun· February 2023

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Large-scale proteomic analysis of muscle-stage ESPs identifies a novel upstream motif for prediction of secreted products.
Bradley Nash, William F Gregory, Rhiannon R White, Anna V Protasio, Steve P Gygi

Front Parasitol· January 2023

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ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2α Axis.
Eduardo Balsa, Meghan S Soustek, Ajith Thomas, Sara Cogliati, Carolina García-Poyatos, Steve P Gygi

Mol Cell· June 2019

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Physical and Molecular Landscapes of Mouse Glioma Extracellular Vesicles Define Heterogeneity.
Aron Gyuris, Jose Navarrete-Perea, Ala Jo, Simona Cristea, Shuang Zhou, Steve P Gygi

Cell Rep· June 2019

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A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine.
Hyun Jung Jun, Vicky A Appleman, Hua-Jun Wu, Christopher M Rose, Javier J Pineda, Steve P Gygi

Nat Commun· August 2018

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Chronic platelet-derived growth factor receptor signaling exerts control over initiation of protein translation in glioma.
Shuang Zhou, Vicky A Appleman, Christopher M Rose, Hyun Jung Jun, Juechen Yang, Steve P Gygi

Life Sci Alliance· June 2018

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Inhibition of the ER stress IRE1α inflammatory pathway protects against cell death in mitochondrial complex I mutant cells.
Meghan S Soustek, Eduardo Balsa, Joeva J Barrow, Mark Jedrychowski, Rutger Vogel, Steve P Gygi

Cell Death Dis· May 2018

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Quantitative Phospho-proteomic Analysis of TNFα/NFκB Signaling Reveals a Role for RIPK1 Phosphorylation in Suppressing Necrotic Cell Death.
Firaz Mohideen, Joao A Paulo, Alban Ordureau, Steve P Gygi, J Wade Harper

Mol Cell Proteomics· July 2017

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Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes.
Kfir Sharabi, Hua Lin, Clint D J Tavares, John E Dominy, Joao Paulo Camporez, Steve P Gygi

Cell· March 2017

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Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations.
Joeva J Barrow, Eduardo Balsa, Francisco Verdeguer, Clint D J Tavares, Meghan S Soustek, Steve P Gygi

Mol Cell· October 2016

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Corrigendum: Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1.
Edward T Chouchani, Lawrence Kazak, Mark P Jedrychowski, Gina Z Lu, Brian K Erickson, Steve P Gygi

Nature· August 2016

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Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation.
Xing Zeng, Mark P Jedrychowski, Yi Chen, Sara Serag, Gareth G Lavery, Steve P Gygi

Genes Dev· August 2016

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Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1.
Edward T Chouchani, Lawrence Kazak, Mark P Jedrychowski, Gina Z Lu, Brian K Erickson, Steve P Gygi

Nature· April 2016

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A creatine-driven substrate cycle enhances energy expenditure and thermogenesis in beige fat.
Lawrence Kazak, Edward T Chouchani, Mark P Jedrychowski, Brian K Erickson, Kosaku Shinoda, Steve P Gygi

Cell· October 2015

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Nucleocytoplasmic transport in the midzone membrane domain controls yeast mitotic spindle disassembly.
Rafael Lucena, Noah Dephoure, Steve P Gygi, Douglas R Kellogg, Victor A Tallada

J Cell Biol· May 2015

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Evidence that a consensus element found in naturally intronless mRNAs promotes mRNA export.
Haixin Lei, Bo Zhai, Shanye Yin, Steve Gygi, Robin Reed

Nucleic Acids Res· February 2013

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