Publications by authors named "Steve W Homans"

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Synthesis of uniformly deuterated n-dodecyl-β-D-maltoside (d39-DDM) for solubilization of membrane proteins in TROSY NMR experiments.
Kazumi Hiruma-Shimizu, Arnout P Kalverda, Peter J F Henderson, Steve W Homans, Simon G Patching

J Labelled Comp Radiopharm· December 2014

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¹H, ¹⁵N, and ¹³C backbone chemical shift assignment of titin domains A59-A60 and A60 alone.
András Czajlik, Gary S Thompson, Ghulam N Khan, Arnout P Kalverda, Steve W Homans

Biomol NMR Assign· October 2014

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TROSY NMR with a 52 kDa sugar transport protein and the binding of a small-molecule inhibitor.
Arnout P Kalverda, James Gowdy, Gary S Thompson, Steve W Homans, Peter J F Henderson

Mol Membr Biol· June 2014

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¹H, ¹⁵N and ¹³C backbone chemical shift assignment of the titin A67-A68 domain tandem.
András Czajlik, Gary S Thompson, Ghulam N Khan, Arnout P Kalverda, Steve W Homans

Biomol NMR Assign· April 2012

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Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid.
Georgina Cox, Gary S Thompson, Huw T Jenkins, Frank Peske, Andreas Savelsbergh, Steve W Homans

Proc Natl Acad Sci U S A· February 2012

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Ligand binding to distinct states diverts aggregation of an amyloid-forming protein.
Lucy A Woods, Geoffrey W Platt, Andrew L Hellewell, Eric W Hewitt, Steve W Homans

Nat Chem Biol· August 2011

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Conformational conversion during amyloid formation at atomic resolution.
Timo Eichner, Arnout P Kalverda, Gary S Thompson, Steve W Homans, Sheena E Radford

Mol Cell· January 2011

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Comparison of entropic contributions to binding in a "hydrophilic" versus "hydrophobic" ligand-protein interaction.
Neil R Syme, Caitriona Dennis, Agnieszka Bronowska, Guido C Paesen, Steve W Homans

J Am Chem Soc· June 2010

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Fibril fragmentation enhances amyloid cytotoxicity.
Wei-Feng Xue, Andrew L Hellewell, Walraj S Gosal, Steve W Homans, Eric W Hewitt

J Biol Chem· December 2009

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Probing dynamics within amyloid fibrils using a novel capping method.
Geoffrey W Platt, Wei-Feng Xue, Steve W Homans, Sheena E Radford

Angew Chem Int Ed Engl· October 2009

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Amyloid fibril length distribution quantified by atomic force microscopy single-particle image analysis.
Wei-Feng Xue, Steve W Homans, Sheena E Radford

Protein Eng Des Sel· August 2009

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Poxvirus K7 protein adopts a Bcl-2 fold: biochemical mapping of its interactions with human DEAD box RNA helicase DDX3.
Arnout P Kalverda, Gary S Thompson, Andre Vogel, Martina Schröder, Andrew G Bowie, Steve W Homans

J Mol Biol· January 2009

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Residual ligand entropy in the binding of p-substituted benzenesulfonamide ligands to bovine carbonic anhydrase II.
Henning Stöckmann, Agnieszka Bronowska, Neil R Syme, Gary S Thompson, Arnout P Kalverda, Steve W Homans

J Am Chem Soc· September 2008

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Perspectives on NMR in drug discovery: a technique comes of age.
Maurizio Pellecchia, Ivano Bertini, David Cowburn, Claudio Dalvit, Ernest Giralt, Steve W Homans

Nat Rev Drug Discov· September 2008

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Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly.
Wei-Feng Xue, Steve W Homans, Sheena E Radford

Proc Natl Acad Sci U S A· July 2008

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Fibril growth kinetics reveal a region of beta2-microglobulin important for nucleation and elongation of aggregation.
Geoffrey W Platt, Katy E Routledge, Steve W Homans, Sheena E Radford

J Mol Biol· April 2008

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Hadamard NMR spectroscopy for relaxation measurements of large (>35 kDa) proteins.
B Tom Burnley, Arnout P Kalverda, Stephen J Paisey, Alan Berry, Steve W Homans

J Biomol NMR· November 2007

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Origin of heat capacity changes in a "nonclassical" hydrophobic interaction.
Neil R Syme, Caitriona Dennis, Simon E V Phillips, Steve W Homans

Chembiochem· September 2007

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Water, water everywhere--except where it matters?
Steve W Homans

Drug Discov Today· July 2007

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Evidence of chemical exchange in recombinant Major Urinary Protein and quenching thereof upon pheromone binding.
Chiara Perazzolo, Mariachiara Verde, Steve W Homans, Geoffrey Bodenhausen

J Biomol NMR· May 2007

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Global changes in local protein dynamics reduce the entropic cost of carbohydrate binding in the arabinose-binding protein.
Christopher A MacRaild, Antonio Hernández Daranas, Agnieszka Bronowska, Steve W Homans

J Mol Biol· May 2007

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Thermodynamic penalty arising from burial of a ligand polar group within a hydrophobic pocket of a protein receptor.
Elizabeth Barratt, Agnieszka Bronowska, Jirí Vondrásek, Jirí Cerný, Richard Bingham, Steve W Homans

J Mol Biol· October 2006

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Contribution of ligand desolvation to binding thermodynamics in a ligand-protein interaction.
Natalia Shimokhina, Agnieszka Bronowska, Steve W Homans

Angew Chem Int Ed Engl· September 2006

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Amyloid formation under physiological conditions proceeds via a native-like folding intermediate.
Thomas R Jahn, Martin J Parker, Steve W Homans, Sheena E Radford

Nat Struct Mol Biol· March 2006

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Strong solute-solute dispersive interactions in a protein-ligand complex.
Richard Malham, Sarah Johnstone, Richard J Bingham, Elizabeth Barratt, Simon E V Phillips, Steve W Homans

J Am Chem Soc· December 2005

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